Tent Inc

RESIDENTIAL (SHELTER AND/OR TRANSITIONAL FOSTER CARE) SERVICES FOR UNACCOMPANIED CHILDREN-LICENSED AND TEXAS-EXEMPT AND FLORIDA-DELICENSED ONLY

ASSISTING THE MOHSS IN PROVIDING CRITICAL HUMAN RESOURCES FOR HEALTH FOR EMERGENCY PREPAREDNESS AND TO ACHIEVE HIV EPIDEMIC CONTROL IN NAMIBIA UNDER THE U.S. PEPFAR - ALIGNED WITH THE ULTIMATE GOAL OF ACHIEVING AN AIDS-FREE NAMIBIAN GENERATION, AS DEFINED IN NAMIBIA?S NATIONAL STRATEGIC FRAMEWORK (NSF) FOR HIV/AIDS RESPONSE, THE CURRENT APPLICATION DETAILS THE APPLICANT?S PLANNED STRATEGIES AND ACTIVITIES TO ASSIST THE MINISTRY OF HEALTH AND SOCIAL SERVICES (MOHSS) IN NAMIBIA, THROUGH THE PROVISION OF CRITICAL HUMAN RESOURCES FOR HEALTH (HRH) SERVICES AND SUPPORT, INCLUDING THE RECRUITMENT OF HRH STAFF FOR PROJECT ACTIVITIES, STRENGTHENING THE MOHSS? CAPACITY FOR HR MANAGEMENT, SUPPORTING THE RETENTION OF COMPETENT PUBLIC HEALTH STAFF FOR PROJECT ACTIVITIES, AND DEVELOPING A SUSTAINABILITY PLAN FOR THE TRANSITIONING OF DONOR-FUNDED HRH FUNCTIONS TO THE NAMIBIAN GOVERNMENT. THE APPLICANT DEMONSTRATES THE WAY IN WHICH ITS? HRH SERVICES WILL AUGMENT THE MOHSS? CAPACITY TO MANAGE HRH AND BETTER EQUIP THE MOHSS TO ACHIEVE ITS GREATER GOALS, INCLUDING REACHING THE 95-95-95 TARGET SET BY THE WORLD HEALTH ORGANIZATION (WHO), MEETING THE PRESIDENT?S EMERGENCY PLAN FOR AIDS RELIEF (PEPFAR) OBJECTIVES, ACHIEVING HIV EPIDEMIC CONTROL (HEC), AND IMPROVING NAMIBIA?S OVERALL PUBLIC HEALTH PREPAREDNESS. A PROJECT LOGIC MODEL, WITH VARIOUS INDICATORS ALIGNED TO THE MAIN GOAL AND OBJECTIVES, HAS BEEN PROVIDED TO MEASURE OUTCOMES MONTHLY, QUARTERLY, AND ANNUALLY. THE APPLICANT HAS DEVELOPED AN EVALUATION AND PERFORMANCE MANAGEMENT PLAN, WHICH OUTLINES PROGRAM IMPLEMENTATION AND PERFORMANCE MONITORING AND EVALUATION ACTIVITIES, FOR THE DURATION OF THE PROJECT. ACCORDING TO THIS PLAN, EACH STRATEGY WILL BE INDIVIDUALLY ASSESSED BASED ON INDICATORS, WITH VARYING DEGREES OF CLARITY BY ENGAGING WITH THE MOHSS. TO DEMONSTRATE EFFECTIVENESS AND EFFICIENCY OF HRH SERVICES IN MOHSS, THE APPLICANT WILL CONDUCT BOTH PROCESS EVALUATIONS AND OUTCOME EVALUATIONS. THE APPLICANT HAS DEVELOPED A DATA MANAGEMENT PLAN, WHICH WILL BE USED TO RECORD DATA AND EFFECTIVE DISSEMINATION OF EVALUATION RESULTS WILL BE ACHIEVED THROUGH PRESENTATIONS OF PRO GRAM EVALUATION REPORTS TO THE MOHSS AND CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC). A WORK PLAN, WHICH INCORPORATES THE REQUIRED ACTIVITIES AND OUTCOMES, HAS BEEN DEVELOPED BY THE APPLICANT FOR THE FIRST YEAR OF FUNDING TOGETHER WITH AN ABRIDGED WORK PLAN FOR THE FOUR SUBSEQUENT YEARS OF FUNDING. THE PROVISION OF TARGETED SUPPORT WITHIN THE IDENTIFIED PRIORITY REGIONS, KHOMAS, OMUSATI, OSHANA, OHANGWENA, OSHIKOTO, ZAMBEZI, AND KAVANGO EAST AND WEST, HAS BEEN PLANNED. THE APPLICANT HAS DRAFTED AN ACCOMPANYING BUDGET, WHICH FALLS WITHIN THE APPROVED LIMITS OF FUNDING. THE APPLICANT HAS DEMONSTRATED ITS ORGANIZATIONAL CAPACITY TO IMPLEMENT THE APPROACH BY HIGHLIGHTING ITS EXPERIENCE IN ALL ASPECTS OF PERSONNEL MANAGEMENT AND LABOR RELATIONS AS WELL AS ITS EXTENSIVE INSIGHTS, EXPERIENCE, ESTABLISHED PROCESSES AND METHODOLOGIES TO EFFECTIVELY MANAGE THE REQUIREMENTS OF UNITED STATES GOVERNMENT (USG)-FUNDING RESPONSIBILITIES AND REPORTING. THE APPLICANT HAS ALSO DEMONSTRATED ITS COLLABORATIVE SKILLS AND ABILITY THROUGH ITS PARTNERSHIPS AND EXPERIENCE WORKING WITH CDC PROGRAMS AND CDC-FUNDED ORGANIZATIONS AS WELL AS OTHER ORGANIZATIONS AND LOCAL AND FOREIGN HEALTH EXPERTS. THE APPLICANT HAS ILLUSTRATED HOW ITS SKILL-, KNOWLEDGE-, AND COMPETENCY-BASE AS WELL AS ITS ADAPTABILITY, DYNAMIC FRAMEWORK, RAPID DECISION-MAKING CAPABILITY, FINANCIAL ABILITY, AND ITS EFFECTIVE ORGANIZATIONAL SIZE, PRESENCE, AND REACH RENDERS IT AN EFFECTIVE CONDUIT THROUGH WHICH PEPFAR FUNDING CAN BE CHANNELED TO ACHIEVE MAXIMUM IMPACT WITHIN A LIMITED TIME FRAME.THE APPLICANT HAS DEMONSTRATED FULL COMPLIANCE WITH THE CDC NOTICE OF FUNDING OPPORTUNITY (NOFO) STATUTORY REQUIREMENTS AND DISCLOSURES. THE APPLICANT IS AN ENTITY OTHER THAN A SOLE PROPRIETORSHIP AND IS INCORPORATED IN THE REPUBLIC OF NAMIBIA. IT IS A COMPANY FULLY OWNED BY NAMIBIAN CITIZE

ASSISTING THE MINISTRY OF HEALTH AND SOCIAL SERVICES (MOHSS) IN PROVIDING CRITICAL HUMAN RESOURCES F

BUILDING HUMAN RESOURCES CAPACITY WITHIN THE MINISTRY OF HEALTH AND SOCIAL SERVIC

RESIDENTIAL SHELTER SERVICES FOR UNACCOMPANIED ALIEN CHILDREN

THE OVERALL GOAL WILL BE TO PROVIDE PROPER PHYSICAL AND RESIDENTIAL SHELTER FOR A DIVERSE POPULATION OF UNACCOMPANIED ALIEN CHILDREN OF ALL AGES AND GENDERS.

BUILDING HUMAN RESOURCE CAPACITY WITHIN THE MINISTRY OF HEALTH & SOCIAL

UNACCOMPANIED ALIEN CHILDREN

USAID ORPHANS AND VULNERABLE CHILDREN RESPONSE IN MANICA

24 BED GROUP HOME CARE IN SOUTHERN CALIFORNIA, LOS ANGELES

SHENANDOAH VALLEY JUVENILE CENTER - OFFICE OF REFUGEE RESETTLEMENT/ DIVISION OF CHILDREN SERVICES RESIDENTIAL (SECURE) SERVICES FOR UNACCOMPANIED CHILDREN

RESIDENTIAL (LONG TERM FOSTER CARE) SERVICES FOR UNACCOMPANIED CHILDREN

CNP HEALTHY MEALS INCENTIVE

RESIDENTIAL SERVICES FOR UNACCOMPANIED ALIEN CHILDREN

COMMUNITY-WIDE TEEN PREGNANCY PREVENTION INITIATIVE

JDCNV PROPOSES TO PROVIDE ORR WITH THREE LEVELS OF SERVICE: 10 SECURE BEDS, 10 STAFF- SECURE BED, AND 3 SHELTER BEDS.

COMMUNITY-BASED WORKFORCE TO INCREASE COVID-19 VACCINATIONS IN UNDERSERVED COMMUNITIES

RESIDENTIAL SECURE SERVICES FOR UNACCOMPANIED ALIEN CHILDREN

THE OVERALL GOAL WILL BE TO PROVIDE PROPER PHYSICAL AND RESIDENTIAL LONG TERM FOSTER CARE FOR A DIVERSE POPULATION OF UNACCOMPANIED ALIEN CHILDREN OF ALL AGES AND GENDERS.

SHENANDOAH VALLEY JUVENILE CENTER - OFFICE OF REFUGEE RESETTLEMENT/ DIVISION OF CHILDREN SERVICES RESIDENTIAL (SECURE) SERVICES FOR UNACCOMPANIED CHILDREN - 10 BED

PROJECT EBAN: MOVING BEYOND THE FENCES - PROJECT EBAN IS A CULTURALLY TAILORED, MULTI-DIMENSIONAL YOUTH DEVELOPMENT INITIATIVE THAT WILL SEEK TO SERVE 2700 HIGH-RISK YOUNG BLACK MALES AGES 13-19 IN THE COUNTIES OF CLAYTON AND MACON-BIBB IN GEORGIA. THE “EBAN” IS THE WEST AFRICAN ADINKRAN SYMBOL FOR “FENCE.” PROJECT EBAN INCREASES THE FENCES OR PROTECTIVE FACTORS THAT PROMOTE POSITIVE MALE DEVELOPMENT, WHILE KEEPING OUT (OR REDUCING) RISK FACTORS. EBAN CREATES PROSOCIAL SPACES THAT CENTER YOUNG BLACK MALES IN A HOST OF INTERRELATED PROGRAM ACTIVITIES THAT SHARE POWER, GIVE THEM AGENCY, AND PROMOTE SOCIAL AND EMOTIONAL DEVELOPMENT.

DEVELOPMENT OF ENABLING VECTOR/ANTIGEN EXPRESSION TECHNOLOGY FOR AN ORALLY-DELIVE

RESIDENTIAL LONG TERM FOSTER CARE SERVICES FOR UNACCOMPANIED ALIEN CHILDREN

COAP CATEGORY 2 NATIONAL TTA PROVIDER

CLEAN AND RENEWABLE ENERGY AND ENERGY EFFICIENCY IN BRAZIL

THE NATIONAL RESOURCE CENTER ON AD/HD: A PROGRAM OF CHADD

ALIGNING COMMUNITY SYSTEMS FOR OPTIMAL ADOLESCENT HEALTH

IMPLEMENTING EVIDENCE-BASED HEALTH PROMOTION PROGRAMS FOR CHILDREN WITH ATTENTION DEFICIT/HYPERACTIVITY DISORDER

PROVIDE SERVICES TO ENSURE THAT THE UAC IS PLACED IN A CONDUCIVE AND NURTURING ENVIRONMENT WHILE PROVIDING CASE MANAGEMENT FOR THE UAC TO SUCCESSFULLY INTEGRATE THEM INTO THEIR ENVIRONMENT

WASTE DISPOSAL GRANTS - REGULAR

SAVE-FISTULAS: A PIVOTAL STUDY OF SELFWRAP-ASSISTED ARTERIOVENOUS FISTULAS - PROJECT SUMMARY/ABSTRACT ARTERIOVENOUS FISTULAS (AVFS), SURGICAL CONNECTIONS OF AUTOGENOUS ARTERIES AND VEINS, ARE CONSIDERED THE GOLD STANDARD FOR HEMODIALYSIS (HD), THE PRIMARY MODE OF SURVIVAL FOR HALF A MILLION AMERICANS WITH FAILED KIDNEYS (PROGRESSIVE CHRONIC KIDNEY DISEASE, CKD) AND MILLIONS MORE GLOBALLY. HOWEVER, 39% OF THE AVFS CREATED IN THE UNITED STATES FAIL TO EVER BE USED FOR DIALYSIS, AND 50% ARE ABANDONED WITHIN 12 MONTHS, GREATLY CONTRIBUTING TO 1- AND 5-YEAR HD MORTALITY RATES OF 21% AND 60%, RESPECTIVELY. THE REASON FOR SUCH HIGH AVF FAILURE RATES IS THAT VEINS ARE THINNER-WALLED AND FAR MORE COMPLIANT THAN ARTERIES, NOT EQUIPPED FOR THE HIGH PRESSURE, HIGH FLOW, PULSATILE ENVIRONMENT OF THE ARTERIAL CIRCULATION. VEINS DRASTICALLY EXPAND AS A RESULT, CAUSING INJURY TO THE PROTECTIVE INNER ENDOTHELIAL LINING OF THE VESSEL THAT LEADS TO MIGRATION AND PROLIFERATION OF VASCULAR SMOOTH MUSCLE CELLS (VSMCS), OR NEOINTIMAL HYPERPLASIA (NH), CAUSING OCCLUSION, LACK OF BLOOD FLOW, AND LOSS OF PATENCY. THIS PROBLEM OF VEINS FAILING TO SUCCESSFULLY ADAPT OR ARTERIALIZE FROM SURGERIES CONNECTING VEINS TO ARTERIES IS TERMED THE ‘ACHILLES HEEL’ OF VASCULAR SURGERY BECAUSE THE PROBLEM IS SO PERVASIVE AND INCORRIGIBLE, GREATLY IMPACTING MORBIDITY AND MORTALITY FOR OVER 5 MILLION NEW PATIENTS EACH YEAR UNDERGOING AVF CREATION, ARTERIOVENOUS GRAFT (AVG) CREATION, PERIPHERAL ARTERY BYPASS GRAFTING (PABG), OR CORONARY ARTERY BYPASS GRAFTING (CABG) SURGERY. TO ADDRESS THIS UNDERLYING PHYSIOLOGICAL PROBLEM, VENOSTENT HAS DEVELOPED THE SELFWRAP BIOABSORBABLE PERIVASCULAR WRAP (I.E. SELFWRAP), A WRAP THAT GOES AROUND THE VEIN AT THE TIME OF THE VEIN-TO-ARTERY CONNECTION SURGERY TO PROVIDE OPTIMAL MECHANICAL SUPPORT AND HELP IT SUCCESSFULLY ARTERIALIZE, WITH A FIRST INDICATION FOR AVFS. SELFWRAP IS COMPRISED OF FINELY-TUNED, BIOABSORBABLE, THERMO-RESPONSIVE SMART POLYMERS AND ITS GEOMETRIC FEATURES ARE OPTIMALLY CONFIGURED TO HELP THE VEIN ADAPT FAVORABLY TO THE ARTERIAL CIRCULATION. THE NET RESULT OF THIS DEVICE IMPACT HAS BEEN A SIGNIFICANT REDUCTION IN NH IN THREE DIFFERENT CHRONIC LARGE ANIMAL MODELS: A DISEASED RABBIT BYPASS GRAFTING MODEL AT 90 DAYS (FUNDED BY THE NIH STTR PHASE I AWARD), OVINE AVFS AT 90,180, AND 365 DAYS (FUNDED BY NSF SBIR PHASE II), AND IN OVINE AVGS AT 60 DAYS. MOST IMPORTANTLY, THE CLINICAL BENEFIT OF THE SELFWRAP DEVICE HAS BEEN DEMONSTRATED IN A 20-PATIENT INITIAL FEASIBILITY STUDY, WHERE VERY HIGH MATURATION RATES, LOW INTERVENTION RATES, HIGH CATHETER REMOVAL RATES, AND HIGH PATENCY WERE ACHIEVED. THESE CLINICAL AND PRECLINICAL RESULTS AWARDED VENOSTENT BREAKTHROUGH DEVICE DESIGNATION FROM FDA IN 2022. THIS PROPOSAL EVALUATES THE SAFETY AND EFFECTIVENESS OF SELFWRAP IN CKD PATIENTS REFERRED FOR CREATION OF A NEW AVF IN A PIVOTAL STUDY. SUCCESSFUL COMPLETION OF THIS PIVOTAL TRIAL, WITH A SIGNIFICANT IMPROVEMENT IN THE PRIMARY OUTCOME AND NO SIGNIFICANT SAFETY CONCERNS USING SELFWRAP, WOULD PROVIDE THE EVIDENCE NEEDED FOR FDA APPROVAL OF THIS BREAKTHROUGH DEVICE. THIS COULD POTENTIALLY REVOLUTIONIZE THE FIELD OF VASCULAR SURGERY, IMPROVING THE QUALITY AND LENGTH OF LIFE FOR MILLIONS OF PATIENTS EACH YEAR THAT UNDERGO AVF, AVG, PABG, OR CABG SURGERY.

DD15-1505-NATIONAL PUBLIC HEALTH PRACTICE AND RESOURCE CENTERS FOR CHILDREN WITH ATTENTION DEFICIT/H

COMMUNITY PROJECT FUNDING/CONGRESSIONALLY DIRECTED SPENDING - CONSTRUCTION - FLORENCE CRITTENTON PROGRAMS, INC., DOING BUSINESS AS CRITTENTON SERVICES, IS A 501(C)(3) NON-PROFIT ORGANIZATION, ESTABLISHED IN 1895, TO PROVIDE TRAUMA-INFORMED BEHAVIORAL AND MENTAL HEALTH SERVICES TO WOMEN, CHILDREN, AND FAMILIES ACROSS WEST VIRGINIA. THE AGENCY OFFERS RESIDENTIAL BEHAVIORAL HEALTH CARE FOR GIRLS AND YOUNG WOMEN ON THE WHEELING CAMPUS, COMMUNITY-BASED MENTAL HEALTH SERVICES FOR RESIDENTS THROUGHOUT THE STATE, AND TRAUMA-INFORMED EDUCATIONAL SERVICES WITHIN OHIO AND HANCOCK COUNTY SCHOOLS. THE MISSION OF THE AGENCY IS TO INSTILL HOPE AND SUPPORT THROUGH A RANGE OF SERVICES THAT EMPOWER INDIVIDUALS, FAMILIES, AND DIVERSE COMMUNITIES TO HEAL, GROW, AND THRIVE. CRITTENTON IS ACCREDITED BY THE COUNCIL ON ACCREDITATION (COA) FOR THE HIGHEST STANDARDS OF PROFESSIONAL PRACTICE. CRITTENTON’S CENTER FOR YOUNG WOMEN AND CHILDREN, THE AGENCY’S RESIDENTIAL TREATMENT PROGRAM, SERVES ADOLESCENT FEMALES AGES 12-21 ACROSS THE STATE, WITH GENDER-SPECIFIC, TRAUMA-FOCUSED BEHAVIORAL HEALTH TREATMENT. THIS INCLUDES A SPECTRUM OF SERVICES SUCH AS PROFESSIONAL COUNSELING, ON-GROUND SCHOOL AND DAYCARE, NURSING CARE, PARENTING EDUCATION, AND LIFE SKILLS DEVELOPMENT. CLIENTS ARE IN THE CUSTODY OF THE STATE AND PLACED IN OUR CARE FOR BEHAVIORAL HEALTH TREATMENT DUE TO HISTORIES OF ABUSE, NEGLECT, ABANDONMENT, ETC. CRITTENTON AIMS TO BREAK CYCLES OF INTERGENERATIONAL POVERTY AND ABUSE BY ADDRESSING THE UNIQUE NEEDS OF MARGINALIZED GIRLS, AND YOUNG MOTHERS. THE AGENCY REMAINS THE ONLY FACILITY IN WEST VIRGINIA LICENSED TO MEET THE SPECIALIZED BEHAVIORAL HEALTH NEEDS OF ADOLESCENT MATERNITY AND PARENTING CLIENTS. CRITTENTON SERVICES IS FULLY ALIGNED WITH WEST VIRGINIA PLAN TO REFORM THE YOUTH SERVICES SYSTEM, SHIFTING THE FOCUS OF RESIDENTIAL PROGRAMS TO SERVE YOUTH REQUIRING INTENSIVE TREATMENT, AND KEEPING CHILDREN WITHIN THE STATE. RESEARCH SHOWS THAT INDIVIDUALS WITH AN ADVERSE CHILDHOOD EXPERIENCE SCORE OF 4 OR GREATER HAVE A HIGHER RISK FOR DEPRE SSION, ANXIETY, SUICIDAL THOUGHTS AND ATTEMPTS, DROPPING OUT OF EDUCATION, UNEMPLOYMENT, AND VARIOUS HEALTH PROBLEMS (MERRICK ET AL., 2019). AN INTERNAL REVIEW OF INTAKE AND ASSESSMENT DATA FROM FISCAL YEAR 2020/2021 REVEALS THAT THE AVERAGE CRITTENTON RESIDENTIAL CLIENT’S ACE SCORE WAS 7.2, EMPHASIZING THE CRITICAL NEED FOR TARGETED INTERVENTIONS. FURTHERMORE, A 2023 STUDY CONDUCTED BY MARSHALL UNIVERSITY FOUND THAT OUT OF THE 909 YOUTH PLACED WITHIN RESIDENTIAL CARE IN WEST VIRGINIA BETWEEN JANUARY 2023 AND SEPTEMBER 2023, 23% WERE PLACED IN OUT-OF-STATE CARE. IN RESPONSE, CRITTENTON INTENDS TO CONSTRUCT TWO NEW RANCH-STYLE RESIDENTIAL INTENSIVE TREATMENT HOMES ON ITS WHEELING CAMPUS TO SERVE ADOLESCENT FEMALES WITH A HIGHER LEVEL OF NEED, INCLUDING THOSE WHO MAY BE PREGNANT AND PARENTING AND THEIR CHILDREN. THESE HOMES WILL PROVIDE SECURE, THERAPEUTIC ENVIRONMENTS CLOSER TO HOME, REDUCING THE ONGOING USE OF OUT-OF-STATE ADOLESCENT RESIDENTIAL SERVICES. THIS CONSTRUCTION PROJECTS ENTAIL THE DEVELOPMENT OF TWO NEW STANDALONE RESIDENTIAL INTENSIVE TREATMENT HOMES ON CRITTENTON SERVICE’S WHEELING CAMPUS, EACH ACCOMMODATING UP TO EIGHT ADOLESCENT FEMALES AND FOUR BABIES. SPANNING APPROXIMATELY 3,000 SQUARE FEET, THESE RESIDENTIAL INTENSIVE TREATMENT HOMES WILL FEATURE SINGLE-STORY LAYOUTS WITH ENHANCED SAFETY MEASURES AND IMPROVED SUPERVISION CAPABILITIES. THIS WILL ENABLE CRITTENTON’S HIGHLY TRAINED STAFF TO PROVIDE IMPROVED COMPREHENSIVE TRAUMA-INFORMED CARE, UTILIZING THE ARC FRAMEWORK, TO YOUNG GIRLS, MOTHERS, AND THEIR CHILDREN. EACH ADA-ACCESSIBLE FACILITY WILL BE EQUIPPED WITH BEDROOMS, BATHROOMS, A CENTRAL DINING AREA, LAUNDRY FACILITIES, A CENTRALIZED OFFICE WITH CLEAR LINE-OF-SIGHT, AND SENSORY SPACES FOR FAMILY VISITS, THERAPY, AND RECREATION. WITH THESE NEW RESIDENTIAL INTENSIVE TREATMENT HOMES, CRITTENTON SERVICES AIMS TO EXPAND OUR CAPACITY TO SERVE ADOLESCENT FEMALE GIRLS, MOTHERS, AND INFANTS IN SMALL, WARM, SAFE, SECURE, AND THERAPEUTIC ENVIRONMENTS WITHIN THE STATE.

PLASMODIUM VIVAX RECOMBINANT CS PROTEIN VACCINE FOR MALARIA

FY19 RSAT TTA PROJECT

RESIDENTIAL SUBSTANCE ABUSE TREATMENT TRAINING AND TECHNICAL ASSISTANCE PROGRAM

COAP CATEGORY B TTA PROVIDER

CRITTENTON CENTER REGIONAL PARTNERSHIP GRANT

WASTE DISPOSAL GRANTS - REGULAR

ECONOMIC DEVELOPMENT INITIATIVE, COMMUNITY PROJECT FUNDING, AND MISCELLANEOUS GRANTS

ECONOMIC DEVELOPMENT INITIATIVE, COMMUNITY PROJECT FUNDING, AND MISCELLANEOUS GRANTS

OPTIMIZED RATIOMETRIC VOLTAGE-SENSITIVE DYES FOR CARDIAC RESEARCH, SAFETY PHARMACOLOGY - PROJECT SUMMARY/ABSTRACT POTENTIOMETRIC PROBES THE OVERALL GOAL OF THIS PHASE II SBIR PROJECT IS TO COMMERCIALIZE TOOLS, INVENTED BY THE FOUNDERS OF POTENTIOMETRIC PROBE, LLC, FOR HIGH-FIDELITY OPTICAL RECORDING OF ELECTRICAL ACTIVITY IN CARDIAC CELLS, TISSUES, AND WHOLE HEARTS. POTENTIOMETRIC PROBES DEVELOPS ORGANIC VOLTAGE-SENSITIVE DYES (VSDS) THAT CONVERT THE CHANGES IN VOLTAGE ACROSS CELL MEMBRANES TO VISIBLE CHANGES IN FLUORESCENCE. INSTEAD OF INDIVIDUAL ELECTRODES, THIS TECHNOLOGY ENABLES THE USE OF SENSITIVE HIGH-SPEED CAMERAS, WHERE EACH PIXEL CAN BE CONSIDERED AN ELECTRODE, FOR MASSIVELY PARALLEL HIGH THROUGHPUT SCREENING, OR FOR HIGH-RESOLUTION SPATIOTEMPORAL MAPS OF ELECTRICAL SIGNAL PROPAGATION. IMPORTANTLY, OUR VSDS ARE UNIQUE IN ENABLING DUAL-WAVELENGTH RATIOMETRIC RECORDING OF ELECTRICAL ACTIVITY; THIS IS PARTICULARLY IMPORTANT FOR CARDIAC STUDIES BECAUSE IT ELIMINATES CONTRACTION-INDUCED MOTION ARTIFACTS, PERMITTING HIGH-FIDELITY RECORDS OF THE ACTION POTENTIAL WAVEFORM. HUMAN STEM CELL-DERIVED CARDIOMYOCYTES (HIPSC-CMS) AND TISSUES DERIVED FROM THEM ARE INCREASINGLY BEING USED FOR RESEARCH AND DEVELOPMENT PURPOSES, INCLUDING SCREENING NEW DRUGS FOR CARDIOTOXICITY, AND IN THE FUTURE MAY BE USED FOR “PERSONALIZED MEDICINE” AND THE ANALYSIS OF PATIENT-DERIVED CELLS. WE BELIEVE HIGH THROUGHPUT RECORDING OF ACCURATE ACTION POTENTIAL WAVEFORMS FROM HIPSC-CMS AND TISSUES WILL BE A MAJOR MARKET FOR THE PROPOSED TECHNOLOGY. ULTIMATELY, THE TECHNOLOGY MAY ALSO BE APPLIED CLINICALLY FOR HIGH-RESOLUTION IMAGING OF ACTION POTENTIAL PROPAGATION IN THE HEART. IN THIS PROPOSAL, POTENTIOMETRIC PROBES WILL SYNTHESIZE A SET OF STABLE, NON-TOXIC RATIOMETRIC VSDS WITH A BROAD SELECTION OF SPECTRAL WINDOWS, ALLOWING ACCURATE RECORDINGS EVEN FROM BEATING HEARTS. THE PERFORMANCE OF THESE VSDS WILL ALSO BE FULLY CHARACTERIZED AND VALIDATED FOR THEIR COMPATIBILITY WITH SENSITIVE CELL LINES FOR BOTH LONG-TERM AND HIGH-THROUGHPUT RECORDINGS.

RESIDENTIAL SUBSTANCE ABUSE TREATMENT FOR STATE PRISONERS TRAINING AND TECHNICAL ASSISTANCE PROGRAM

OPTIMIZE THE DESIGN OF THE DUO-DS WAVE-POWERED DESALINATION SYSTEM, BUILDING ON THE DEVICE DESIGNED FOR THE WAVES-TO-WATER PRIZE. THIS PROJECT UPDATES THE SPECIFICATION OF THE DUO-DS FOR MARKETS ASSOCIATED WITH REMOTE COASTAL COMMUNITIES AND SALMON FARMING. THE PROJECT WILL DESIGN, BUILD, TEST, AND QUALIFY A FULL-SCALE DEVICE FOR THESE TARGET MARKETS, INCLUDING IN AN OPEN WATER TEST SITE TO ADVANCE THE TECHNOLOGY READINESS FROM TRL6 TO TRL8 AND DEMONSTRATE READINESS FOR COMMERCIAL DEPLOYMENT IN A DEMONSTRATION PROJECT BEFORE 2025. THE PROJECT INCLUDES COLLABORATION WITH THE MARINE RENEWABLE ENERGY COLLABORATIVE OF NEW ENGLAND FOR PERMITTING REQUIREMENTS, PURE MARINE GEN FOR MODELLING EXPERTISE AND DESIGN INPUTS TO THE WAVE POWER SYSTEM, AND COLLOIDE ENGINEERING FOR WATER TREATMENT EXPERTISE AND DESIGN INPUTS INTO THE WATER TREATMENT PORTION OF THE SYSTEM. THE PROJECT WILL ALSO COMPLETE A PERFORMANCE ASSESSMENT IN LINE WITH THE INTERNATIONAL ELECTROTECHNICAL COMMISSION STANDARDS THAT WILL INFORM PREPARATION ON NEW IEC TECHNICAL SPECIFICATIONS FOR WAVE POWERED DESALINATION SYSTEMS. THE PROJECT WILL ACCELERATE THE COMMERCIALIZATION OF THE DUO-DS WAVE POWERED DESALINATION SYSTEM TO BENEFIT BLUE ECONOMY MARKETS.

IMPLEMENTING EVIDENCE-BASED HEALTH PROMOTION PROGRAMS FOR ATTENTION-DEFICIT HYPERACTIVITY DISORDER (ADHD) - ATTENTION-DEFICIT/HYPERACTIVITY DISORDER (ADHD) IS A NEURODEVELOPMENTAL DISORDER THAT IS USUALLY FIRST DIAGNOSED IN CHILDHOOD AND OFTEN CONTINUES INTO ADULTHOOD. IT CAN LEAD TO SERIOUS PROBLEMS, INCLUDING POOR RELATIONSHIPS, FAMILY STRESS, MISBEHAVIOR, PROBLEMS AT SCHOOL, JOB FAILURE, OBESITY, AND AN INCREASED RISK FOR ACCIDENTAL INJURIES. INFORMATION AND EDUCATION ON ADHD THAT IS BASED ON BEST EVIDENCE IS KEY TO PROPERLY MANAGING ADHD. CHADD, INC. (CHILDREN AND ADULTS WITH ATTENTION-DEFICIT/HYPERACTIVITY DISORDER) IS THE NATION’S LEADING NONPROFIT ORGANIZATION DEDICATED TO IMPROVING THE LIVES OF CHILDREN, ADULTS, AND FAMILIES AFFECTED BY ADHD. SINCE 2002, CHADD’S NATIONAL RESOURCE CENTER ON ADHD (NRC) HAS SERVED AS THE CLEARINGHOUSE FOR EVIDENCE-BASED INFORMATION ON ADHD, SUPPORTING INDIVIDUALS WITH THE DISORDER, THEIR FAMILIES, AND THE HEALTHCARE PROVIDERS AND EDUCATORS INVOLVED IN THEIR LIVES. CHADD’S NRC PROPOSES TO IMPLEMENT EVIDENCE-BASED HEALTH PROMOTION PROGRAMS FOR ADHD. THE STRATEGIES AND ACTIVITIES OF THESE PROGRAMS WILL IDENTIFY THE NEEDS THAT INDIVIDUALS WITH ADHD, THEIR FAMILIES, HEALTHCARE PROVIDERS, AND EDUCATORS HAVE FOR MANAGING ADHD. CHADD’S NRC WILL MEET THESE NEEDS BY CREATING COMMUNICATION AND EDUCATION PROGRAMS, PRODUCTS, TOOLS AND SUPPORTS THAT ARE BASED ON RELIABLE EVIDENCE AND ARE APPROPRIATE FOR EACH OF THE AUDIENCES. SINCE ADHD EXISTS FOR ALL RACES, ETHNICITIES, AND IN ALL GEOGRAPHIC AREAS, THE PROGRAMS WILL REACH OUT TO A DIVERSE AUDIENCE, ESPECIALLY TO THE COMMUNITIES AFFECTED BY HEALTH AND EDUCATIONAL DISPARITIES. FOR INDIVIDUALS WITH ADHD, THEIR FAMILIES, AND COMMUNITIES, THE PROGRAMS WILL IMPROVE THEIR ACCESS TO RELIABLE INFORMATION, SUPPORT, AND SERVICES THAT WILL IMPROVE THEIR LIVES. THE PROGRAMS WILL PROVIDE EDUCATION, TRAINING, AND SUPPORT TO HEALTHCARE PROVIDERS SO THAT THEY CAN PROPERLY DIAGNOSE AND TREAT PEOPLE WITH ADHD. EDUCATORS WILL BE PROVIDED WITH EDUCATION AND TRAINING SO THAT THEY WILL USE EVIDENCE-BASED TEACHING STRATEGIES TO HELP THEIR STUDENTS WITH ADHD SUCCEED IN SCHOOL. CHADD’S RESIDENT EXPERT AND PROFESSIONAL ADVISORY BOARD MEMBERS WILL REVIEW THE SCIENTIFIC EVIDENCE FOR ALL THE EDUCATIONAL RESOURCES THAT ARE DEVELOPED. CHADD WILL COLLABORATE WITH THE CDC TO MEET PROGRAM GOALS AND SUPPORT CDC’S INTERESTS. CHADD WILL ALSO COLLABORATE WITH VARIOUS ADHD EXPERTS AND PROFESSIONAL GROUPS, INCLUDING THE ANNUAL INTERNATIONAL CONFERENCE ON ADHD ORGANIZING COMMITTEE, TO DEVELOP EDUCATION AND TRAINING PROGRAMS FOR HEALTHCARE PROVIDERS AND EDUCATORS. CHADD’S ADHD COMMUNITIES TOGETHER (ACT) PROGRAM WILL CONTINUE TO REACH RACIAL, ETHNIC, AND RURAL COMMUNITIES THROUGH NEW AND EXISTING COLLABORATIONS. TO INCREASE DISSEMINATION OF PROGRAM MATERIALS, CHADD WILL COLLABORATE WITH OTHER MENTAL HEALTH AND EDUCATOR ASSOCIATIONS. CHADD’S SUPPORT GROUPS, SPECIFICALLY THE CHADD REGIONAL CENTERS, WILL COLLABORATE WITH PUBLIC AND PRIVATE SECTORS, INCLUDING BUSINESSES, PROFESSIONAL ASSOCIATIONS, UNIVERSITIES, SCHOOL SYSTEMS, AND OTHER CONCERNED GROUPS WITHIN THEIR COMMUNITIES. PROGRAM ACTIVITIES WILL BE WIDELY PUBLICIZED ON SOCIAL MEDIA PLATFORMS, WEBSITE, AND NEWSLETTERS. THEY WILL BE EVALUATED THROUGHOUT THE YEAR TO IMPROVE PROCESSES AND DEVELOP NEW MATERIALS AND PROGRAMS WHEN AND WHERE THEY ARE NEEDED.

AHP OFFERS A COLLABORATIVE, STRENGTHS-BASED, CULTURALLY COMPETENT, AND RESULTS-DRIVEN APPROACH TO TTA THAT HAS ANTICIPATED AND MET THE NEEDS OF RSAT GRANTEES FOR MORE THAN A DECADE. THE AHP RSAT TEAM COMPRISES SUBJECT MATTER EXPERTS FROM AHP, TASC, AND CCI—THREE AGENCIES NATIONALLY RECOGNIZED FOR THEIR COMMITMENT TO IDENTIFYING AND REPLICATING EFFECTIVE STRATEGIES FOR PREPARING INDIVIDUALS FOR REINTEGRATION INTO THEIR COMMUNITIES. THE TEAM WILL CONTINUE BUILDING ON THE FOUNDATION IT LAID IN PROMISING PRACTICES GUIDELINES FOR RESIDENTIAL SUBSTANCE ABUSE TREATMENT AND JAIL-BASED MEDICATION ASSISTED TREATMENT: PROMISING PRACTICES, GUIDELINES, AND RESOURCES FOR THE FIELD BY ACTIVELY PROMOTING MAT AND ADHERENCE TO RSAT STANDARDS THROUGH ITS FIDELITY ASSESSMENT INITIATIVE, WHICH HAS ALREADY MADE A DIFFERENCE IN 58 FACILITIES IN 23 STATES AND U.S. TERRITORIES. THE TEAM WILL CONTINUE TO MAINTAIN AND ENHANCE THE RSAT TTA WEBSITE THAT (1) FEATURES AN INNOVATIVE GEOMAP AND COMPENDIUM IDENTIFYING ALL ACTIVE RSAT PROGRAMS ACROSS THE UNITED STATES AND ITS TERRITORIES, THEREBY FACILITATING ESTABLISHMENT OF LEARNING COMMUNITIES; (2) PROVIDES EASY AND TIMELY ACCESS TO TOOLKITS, TTA AND FUNDING OPPORTUNITIES, FEATURE ARTICLES, FEDERAL AND PROFESSIONAL PUBLICATIONS, AND RESEARCH STUDIES OF INTEREST TO THE RSAT AUDIENCE; AND (3) ANSWERS QUESTIONS DIRECTLY POSED BY RSAT STAFF IN THE POPULAR “FORUM.” THE TEAM WILL COORDINATE ADDITIONAL PEER HOST TRAININGS TO GATHER CORRECTIONAL TEAMS AT MODEL PRISON AND JAIL PROGRAMS. OTHER TTA ACTIVITIES INCLUDE DEVELOPING AND DISSEMINATING CURRICULA (INCLUDING EXPANSION OF CURRENT CURRICULA TO INCLUDE EMERGING RESEARCH FINDINGS, FACILITATOR MANUALS, AND SLIDE DECKS); GUIDANCE ON SUBSTANCE USE DISORDER TREATMENT PROGRAMS FOR PRE-TRIAL DETAINEES AND ON INCORPORATING DIVERSITY, EQUITY, AND INCLUSION PRINCIPLES INTO RSAT PROGRAMMING, AS WELL AS POLICY BRIEFS AND FACT SHEETS; MONTHLY WEBINARS FEATURING TOPICS OF INTEREST AND IMPORTANCE TO THE FIELD; AND VIDEOS SHOWCASING MODEL RSAT PROGRAMS, AS WELL AS A VIDEO FEATURING THE PATHWAYS TAKEN BY SEVEN DIFFERENT JAILS TO IMPLEMENT COMPREHENSIVE MAT AND AFTERCARE PROGRAMS TO FIT THEIR JURISDICTIONS. TO CONTINUE RAISING AWARENESS OF RSAT AND TTA OPPORTUNITIES, THE TEAM WILL PRESENT AT RELEVANT NATIONAL CONFERENCES AND ENGAGE ITS UP-TO-DATE LISTSERV OF STATE ADMINISTERING AGENCIES. FURTHER, THE TEAM WILL WORK WITH BJA TO ENGAGE IN CROSS-ORGANIZATIONAL COORDINATION AMONG LOCAL JURISDICTIONS, FEDERAL PARTNERS, AND INTEREST GROUPS.

HOMELESS VETERANS (HVRP)

THE NPHPRC DEVELOPS AND PROVIDES HEALTH PROMOTION PROGRAMS AND HEALTH COMMUNICATI

NATIONAL CRITTENTON AND THE OJJDP GIRLS TTA TEAM UNDERSTANDS THE GOAL OF REDUCING RISK FOR GIRLS IN THE JUVENILE JUSTICE SYSTEM IS TO REDUCE RISK FACTORS AND PROMOTE PROTECTIVE FACTORS FOR GIRLS WHO COME IN CONTACT WITH THE JUVENILE JUSTICE SYSTEM, AND PLACE THEM ON A PATH TOWARD SUCCESS, STABILITY, AND LONG-TERM CONTRIBUTION TO SOCIETY. TO ACHIEVE THIS GOAL, THE OJJDP GIRLS TTA TEAM’S OBJECTIVES ARE TO: 1. EXPAND THE SKILLS OF PROGRAM PROVIDERS AND OTHER STAKEHOLDERS WORKING WITH THE TARGET POPULATION OF GIRLS IN THE JUVENILE JUSTICE SYSTEM; 2. ASSIST PROGRAM PROVIDERS WITH IMPROVING JUVENILE JUSTICE SYSTEM RESPONSES FOR GIRLS IN CONTACT WITH THE SYSTEM. NATIONAL CRITTENTON (NC) LEAD APPLICANT, THE NATIONAL COUNCIL OF JUVENILE AND FAMILY COURT JUDGES (NCJFCJ) SUBRECIPIENT, THE ASSESSMENT TEAM AND THE CORE CONSULTANTS OF GIRL EXPERTS ARE THE PROVIDERS OF TRAINING AND TECHNICAL ASSISTANCE. ADDITIONAL EXPERTS OUTSIDE OF THE CORE CONSULTANTS WILL BE ENGAGED AS APPROPRIATE BASED ON TRAINING AND TECHNICAL ASSISTANCE NEEDS. OJJDP GIRLS TTA ACTIVITIES WILL INCLUDE THE DEVELOPMENT OF CUSTOMIZED GIRLS TTA PLANS FOR CATEGORY 1 PROJECT SITES FOR THE PROVISION OF VIRTUAL AND IN-PERSON TRAINING AND TECHNICAL ASSISTANCE; DEVELOPMENT AND DISSEMINATION OF RESOURCES ON GIRLS; AND OTHER FORMS OF TTA SUCH AS PEER-TO-PEER LEARNING, WEBINARS, ETC.

COOKSTOVE PROJECT - DIV

OJJDP FY 2016 NATIONAL GIRLS INITIATIVE

CENTERS FOR INDEPENDENT LIVING - CENTERS FOR INDEPENDENT LIVING

SBIR PHASE II: ADAPTABLE INVENTION DISCLOSURE SYSTEM

SBIR PHASE II: HEMODYNAMIC OPTIMIZATION AND PRECLINICAL ASSESSMENT OF A SHAPE MEMORY POLYMER WRAP TO REDUCE HEMODIALYSIS ACCESS SITE FAILURES

A NOVEL AGENT FOR PREVENTING FATTY DEGENERATION OF MUSCLES IN LGMD2B - ABSTRACT MUSCULAR DYSTROPHIES ARE GRAVE GENETIC DISORDERS CHARACTERIZED BY MUSCLE WASTING AND PROGRESSIVE LOSS OF MUSCLE FUNCTION. APPROXIMATELY 250,000 INDIVIDUALS ARE CURRENTLY AFFECTED BY SOME FORM OF MD IN THE US. ALTHOUGH MDS ARE CAUSED BY MUTATIONS IN DIFFERENT GENES, THE MUSCLE PATHOLOGIES PATIENTS DEVELOP ARE SHARED AND MANIFEST AS MUSCLE FATTY DEGENERATION (FD) THROUGH REPLACEMENT OF NECROTIC MUSCLE FIBERS BY ADIPOSE AND FIBROTIC TISSUE LEADING TO LOSS OF MUSCLE FUNCTION. LIMB GIRDLE MUSCULAR DYSTROPHY 2B (LGMD2B) AFFECTS SHOULDER AND HIP MUSCLES FIRST, AND RESULTS IN SEVERE DISABILITY AND LOSS OF AMBULATION BY A PATIENT’S SECOND OR THIRD DECADE. THERE IS CURRENTLY NO CURE OR THERAPY FOR LGMD2B SINCE GLUCOCORTICOIDS, WHICH ARE THE STANDARD-OF-CARE FOR SOME TYPES OF MD, ARE NOT ADVISED FOR LGMD2B. WE PROPOSE TO DEVELOP ADVERTENT BIOTHERAPEUTIC’S PROPRIETARY AGENT ADA011, A SPECIFIC TGF-Β1/3 INHIBITOR, INTO A THERAPY THAT INHIBITS MUSCLE FD AND PRESERVES MUSCLE FUNCTION IN LGMD2B PATIENTS. WE IDENTIFIED ADA011 AS A POTENT INHIBITOR OF DE NOVO ADIPOGENESIS IN VITRO AND HAVE NOW DEMONSTRATED THAT ADA011 INHIBITS MUSCLE FD AND DISEASE PROGRESSION IN A MOUSE MODEL OF LGMD2B (I.E., BLA/J MICE). IN ADDITION, WE SHOWED THAT ADA011 HAS FAVORABLE PHARMACOKINETICS AND IS SAFE IN MICE. IN THIS PHASE 2 PROPOSAL WE WILL DEMONSTRATE LONG-TERM EFFICACY OF ADA011 IN BLA/J MICE AND DEMONSTRATE SAFETY IN AN IND-ENABLING STUDY GLP TOXICITY STUDY IN RATS.

RSAT TTA

SBIR PHASE II: PROACTIVE NETWORK CONFIGURATION ANALYSIS

RESEARCH AND EVALUATION ON DOMESTIC TERRORISM PREVENTION, FISCAL YEAR 2021

WILL TO WAIT COMMUNITY-BASED ABSTINENCE PROGRAM

CRITTENTON CENTER STREET OUTREACH PROGRAM (SOP) FOR YOUTH - PROJECT ABSTRACT SUMMARY PROJECT NAME: CRITTENTON CENTER STREET OUTREACH PROGRAM (SOP) FOR YOUTH APPLICANT: FLORENCE CRITTENTON HOME DBA CRITTENTON CENTER PROJECT SUMMARY: THE PROPOSED PROGRAM IS DESIGNED TO PROVIDE STREET-BASED OUT-REACH SERVICES TO RUNAWAY, HOMELESS, AND STREET YOUTH UP TO THE AGE OF 26 TO HELP THEM OUT OF HOMELESSNESS AND MOVE THEM INTO SAFE AND STABLE HOUSING, REBUILDING CONNECTIONS WITH CARING ADULTS AND CREATING PATHWAYS TO ACCESS OTHER COMMUNITY SERVICES AND SUPPORTS. TARGET POPULATION: THE TARGET POPULATION IS RUNAWAY, HOMELESS, AND STREET YOUTH UP TO THE AGE OF 26 WHO ARE EXPERIENCING HOMELESSNESS OR HOUSING INSTABILITY DUE TO A SUBSTANCE ABUSE DISORDER (SUD), CO-OCCURRING DISORDER (COD), AND/OR OTHER BEHAVIORAL HEALTH CONDITIONS. DEMOGRAPHIC CHARACTERISTICS OF TARGET POPULATION: THE PRIMARY GEOGRAPHIC SERVICE AREA IS SIOUX CITY (85,617), WOODBURY COUNTY, IOWA (105,506). REFERRALS MAY BE ACCEPTED FROM FIVE SURROUNDING COUNTIES: CHEROKEE (11,503), CRAWFORD (16,193), IDA (6,596), MONONA (8,574), AND PLYMOUTH (25,650), WITH A FIVE-COUNTY POPULATION OF 68,516 (CENSUS ESTIMATES, JULY 2021). STRATEGIES AND INTERVENTIONS: OUTPATIENT BEHAVIORAL HEALTH THERAPY, INTENSIVE CASE MANAGEMENT, SCREENING AND ASSESSMENT, AND TRAINING AND EDUCATION. EVIDENCE-BASED STRATEGIES AND INTERVENTIONS: MOTIVATIONAL INTERVIEWING (MI), SCREENING, BRIEF INTERVENTION, AND REFERRAL TO TREATMENT (SBIRT), BRIEF INTERVENTIONS AND BRIEF THERAPIES FOR SUBSTANCE ABUSE, COGNITIVE BEHAVIORAL THERAPY (CBT), TRAUMA-FOCUSED COGNITIVE BEHAVIORAL THERAPY (TF-CBT), DIALECTICAL BEHAVIORAL THERAPY (DBT), AND MINDFULNESS-BASED COGNITIVE THERAPY (MBCT). PROJECT GOALS: GOAL I: TO CREATE THE ORGANIZATIONAL CAPACITY TO IMPLEMENT GRANT ACTIVITIES, ENSURING THE REQUIRED ELEMENTS OF THE GRANT ARE DELIVERED ON TIME AND AS INTENDED, AND DEVELOP AND ADVANCE INTERVENTIONS THROUGH COLLABORATION WITH HOUSING AND OTHER LOCAL COMMUNITY PARTNERSHIPS. GOAL 2: TO EQUIP PROJECT STAFF WITH SKILLS, KNOWLEDGE, AND RESOURCES TO PROVIDE HIGH QUALITY, EVIDENCE-BASED, TRAUMA-INFORMED, AND CULTURALLY RESPONSIVE SERVICES, FOR YOUTH EXPERIENCING OR AT-RISK FOR HOMELESSNESS. GOAL III: TO ENSURE YOUTH ARE ABLE TO EASILY ACCESS TRAUMA-INFORMED BEHAVIORAL HEALTH SERVICES, RESOURCES, AND SUPPORTS ALONG A CONTINUUM OF PREVENTION, EARLY INTERVENTION, TREATMENT, AND FOLLOW-UP. GOAL IV: TO COLLABORATE WITH OTHER YOUTH SERVING SYSTEMS, SUCH AS BEHAVIORAL HEALTH, CHILD WELFARE, LAW ENFORCEMENT, JUVENILE JUSTICE, HOUSING, AND OTHER COMMUNITY AGENCIES TO RAISE AWARENESS ON TRAUMA-INFORMED PRACTICES AND PROGRAM SERVICES, ENROLL AND SERVE YOUTH, AND ENHANCE PROGRAM SERVICES. NUMBER TO BE SERVED ANNUALLY AND OVER FIVE-YEAR PROJECT: YEAR 1-30, YEAR 2-40, YEAR 3-50, YEAR 4-50, YEAR 5-50, TOTAL-220. (UNDUPLICATED COUNT)

TRANSFORM MENTAL AND BEHAVIORAL HEALTH

WASTE DISPOSAL GRANTS - REGULAR

HEALING IS FOR EVERYONE: BRINGING SERVICES TO INCARCERATED SEXUAL ABUSE SURVIVORS

NATIONAL CRITTENTON, THE NATIONAL COUNCIL OF JUVENILE AND FAMILY COURT JUDGES (SUBRECIPIENT), THE ASSESSMENT TEAM, AND THE CORE CONSULTANTS OF GIRL EXPERTS WILL PROVIDE TRAINING AND TECHNICAL ASSISTANCE TO GRANTEES TO STRENGTHEN THE PROGRAMS AND SUPPORTS AVAILABLE TO GIRLS AND THEIR FAMILIES IN COMMUNITIES THAT HAVE BEEN HISTORICALLY UNDERSERVED. THE TRAINING AND TECHNICAL ASSISTANCE TEAM WILL ALSO INTEGRATE, SUPPORT, AND SUSTAIN MEANINGFUL YOUTH AND FAMILY PARTNERSHIPS BY ADDING YOUTH AND FAMILIES TO THE CORE EXPERTS TEAM. NATIONAL CRITTENTON AND THE OJJDP GIRLS TRAINING AND TECHNICAL ASSISTANCE TEAM WILL DEVELOP CUSTOMIZED TRAINING AND TECHNICAL ASSISTANCE PLANS FOR PROJECT SITES FOR THE PROVISION OF TRAINING AND TECHNICAL ASSISTANCE, DEVELOP AND HOST AN ANNUAL MEETING FOR ALL GRANTEES, DISSEMINATE RESOURCES ON GIRLS, AND PROVIDE OTHER FORMS OF TRAINING AND TECHNICAL ASSISTANCE, INCLUDING PEER-TO-PEER LEARNING OPPORTUNITIES AND WEBINARS. ADDITIONALLY, DUE TO THE COMPLEXITY OF THE DRIVERS OF GIRLS INTO THE JUVENILE JUSTICE SYSTEM, NATIONAL CRITTENTON WILL ENGAGE A BROAD ARRAY OF STAKEHOLDERS IN ITS EFFORT TO CREATE AND SUSTAIN SYSTEM AND PROGRAMMATIC CHANGE.

TLP

NIJ-EVALUATION OF RURAL DOMESTIC VIOLENCE AND CHILD VICTIMIZATION ENFORCEMENT FAITH BASED INITIATIVE

EBAN INITIATIVE (TIER 1)

SBIR PHASE II: PATENT END-TO-END (PE2E) EXAMINATION

THE CHILD AND ADOLESCENT SUPPORT ADVOCACY AND RESOURCE CENTER OFFERS TRAUMA-FOCUSED PSYCHOTHERAPY AND EDUCATIONAL TRAINING TO DIVERSE GROUPS, INCLUDING COMMUNITY PROVIDERS AND YOUTH. DUE TO INCREASED DEMAND, THIS GRANT AIMS TO BUILD A NEW UNIT AT ZUCKERBERY SAN FRANCISCO GENERAL HOSPITAL, ENHANCING ACCESSIBILITY AND COLLABORATION WITH THE EMERGENCY DEPARTMENT. THE SECURE TUNNEL ACCESS WILL FACILITATE IMPROVED PATIENT CARE, EVIDENCE INTEGRITY, AND SAFETY PROTOCOLS FOR INTERACTIONS INVOLVING LAW ENFORCEMENT, STRENGTHENING OVERALL SERVICE DELIVERY.

ATTENTION, INC. TRANSITIONAL LIVING PROGRAM APPLICATION

GREATER KANSAS CITY CRIME PREVENTION INITIATIVES

TRANSITIONAL LIVING PROGRAM

THE COMMUNITY BASED DOULA PROGRAM

HOST HOME PROGRAM FOR PREGNANT AND PARENTING YOUTH EXPERIENCING HOMELESSNESS

TGTHR TRANSITIONAL LIVING PROGRAM FOR BOULDER COUNTY

THE OFFICE ON VIOLENCE AGAINST WOMEN (OVW) EMERGING ISSUES AND TRAINING AND TECHNICAL ASSISTANCE CALL FOR CONCEPT PAPERS (CALL FOR CONCEPT PAPERS) INVITEDINTERESTED ELIGIBLE ENTITIES TO PROPOSE PROJECTS THAT EXPLORE NEW AND EMERGING ISSUES AND TRAINING AND TECHNICAL ASSISTANCE PROJECTS ADDRESSING THE NEEDS AND CHALLENGES OF OVW GRANTEES, SUBGRANTEES, AND THE LARGER VIOLENCE AGAINST WOMEN FIELD. IN PARTICULAR, WITH THE PASSAGE OF THE VIOLENCE AGAINST WOMEN ACT REAUTHORIZATION ACT OF 2022 (VAWA 2022), PUB. L. NO. 117-103, DIV. W, 136 STAT. 49, 840-962, OVW SOUGHT TO IDENTIFY INNOVATIVE PROJECTS AND TECHNICAL ASSISTANCE THAT ADDRESS THE NEW AND REVISED PROGRAMS AND ISSUES INCLUDED IN VAWA 2022, AS WELL AS OTHER EMERGING ISSUES IN THE FIELDS OF SEXUAL ASSAULT, DOMESTIC VIOLENCE, DATING VIOLENCE, AND STALKING. SEE 34 U.S.C. 12291(B)(11) AND (16). OVW REVIEWED THE SUBMITTED CONCEPT PAPERS, SELECTED PROMISING PROJECTS IN EACH OF THE CALL FOR CONCEPT PAPERS PURPOSE AREAS, AND CONTACTED SELECTED APPLICANTS TO INVITE THEM TO SUBMIT A FULL APPLICATION FOR THEIR CONCEPT PAPER THROUGH THE CALL FOR CONCEPT PAPERS INVITATION TO APPLY SOLICITATION. WITH FUNDING THROUGH THE OVW FY 2023 EMERGING ISSUES AND TRAINING AND TECHNICAL ASSISTANCE CALL FOR CONCEPT PAPERS, JUST DETENTION INTERNATIONAL (JDI) WILL IMPLEMENT THE ROOTED IN RESILIENCE PROJECT. THIS PROJECT WILL EXPAND ADVOCACY SERVICES FOR CURRENTLY AND FORMERLY INCARCERATED SEXUAL ABUSE SURVIVORS BY BUILDING THE CAPACITY OF SEXUAL ASSAULT SERVICE ORGANIZATIONS AND OTHER SURVIVOR SERVICE ORGANIZATIONS TO ESTABLISH SUSTAINABLE, TRAUMA-INFORMED ART WORKSHOPS IN A WIDE VARIETY OF DETENTION AND REENTRY FACILITIES IN COMMUNITIES THROUGHOUT THE UNITED STATES. OVER THE COURSE OF THE PROJECT PERIOD, JDI AND ITS PROJECT PARTNERS WILL: 1) RECRUIT AND TRAIN A DIVERSE GROUP OF SURVIVOR SERVICE PROVIDERS TO FACILITATE ART WORKSHOPS IN SUCH FACILITIES; 2) PROVIDE ONGOING TRAINING AND TECHNICAL ASSISTANCE TO ALL FACILITATORS AS THEY ESTABLISH ART PROGRAMS IN THEIR LOCAL FACILITIES; AND 3) DOCUMENT AND DISSEMINATE PROJECT TOOLS AND SUCCESSES SO THAT OTHER SERVICE PROVIDERS CAN REPLICATE THE PROGRAM IN THEIR OWN COMMUNITIES. THIS AWARD SUPPORTS PURPOSE AREA 1: EMERGING ISSUES. THE TIMING FOR PERFORMANCE OF THIS PROPOSAL IS 36 MONTHS FOR $750,000; ALL OF WHICH WILL BE AWARDED THROUGH OVW TECHNICAL ASSISTANCE FUNDING.

THROUGH RESTORING YOUTH: SUPPORTING SEXUAL ABUSE SURVIVORS IN YOUTH DETENTION, JUST DETENTION INTERNATIONAL (JDI) WILL PROVIDE TRAINING AND TECHNICAL ASSISTANCE AIMED AT EXPANDING SERVICES FOR SEXUAL ABUSE SURVIVORS IN YOUTH DETENTION. JDI’S PARTNER IN THIS PROJECT IS THE LOVE MORE MOVEMENT (LMM), A CULTURALLY SPECIFIC ORGANIZATION WITH EXPERTISE WORKING WITH BLACK YOUTH AND OTHER YOUTH OF COLOR WHO HAVE SURVIVED TRAUMA. IN PARTICULAR, JDI AND LMM WILL BUILD THE CAPACITY OF FOUR SELECTED GRANTEE PARTNERSHIP SITES, COMPRISED OF YOUTH DETENTION FACILITIES AND COMMUNITY-BASED SEXUAL ABUSE SURVIVOR SERVICE PROVIDERS, TO ESTABLISH SERVICES FOR YOUTH THAT ARE ROOTED IN RACIAL EQUITY, AND ACCESSIBLE TO SURVIVORS FROM TRADITIONALLY UNDERSERVED COMMUNITIES. JDI WILL WORK WITH EACH SET OF PARTNERS TO SUPPORT THEM IN NEGOTIATING AND ESTABLISHING MOUS, DETENTION FACILITY-BASED SARTS, AND SEXUAL ABUSE RESPONSE PROTOCOLS ENSURING THAT FACILITY STAFF AND SERVICE PROVIDERS UNDERSTAND THEIR ROLE IN RESPONDING TO YOUTH SURVIVORS OF SEXUAL ABUSE AND THAT YOUTH CAN GET THE HELP THEY NEED TO HEAL.   FOR SERVICE PROVIDERS, JDI AND LMM WILL DEVELOP AND PROVIDE TRAINING AND COACHING AIMED AT BUILDING THEIR CAPACITY TO PROVIDE SERVICES TO YOUTH SURVIVORS FROM UNDERSERVED COMMUNITIES, INCLUDING YOUTH OF COLOR, LGBTIQ+ YOUTH, AND YOUTH WITH DISABILITIES. JDI AND LMM WILL ALSO COLLABORATE WITH SERVICE PROVIDERS TO DEVELOP A YOUTH EDUCATION PROGRAM THAT ADDRESSES SEXUAL ABUSE PREVENTION, HEALTHY RELATIONSHIPS AND COMMUNICATION, AND HEALING FROM TRAUMA.   FOR DETENTION FACILITY STAFF, JDI AND LMM WILL DEVELOP AND PROVIDE TRAINING AND COACHING AIMED AT BUILDING THEIR CAPACITY TO UNDERSTAND: TRAUMA AND ITS EFFECTS ON THE YOUTH IN THEIR CARE; ADOLESCENT DEVELOPMENT, WITH A FOCUS ON SEXUALITY AND GENDER IDENTITY; HOW TO DEVELOP HEALTHY, PROFESSIONAL RELATIONSHIPS WITH DETAINED YOUTH; AND HOW TO INTERVENE TO PROTECT YOUTH WHEN THEY OBSERVE COLLEAGUES ENGAGING IN INAPPROPRIATE CONDUCT. JDI WILL ALSO SUPPORT FACILITY STAFF IN DEVELOPING AND IMPLEMENTING SCREENING PROTOCOLS TO IDENTIFY NEW STAFF WITH CAPACITY TO BUILD PROFESSIONAL, CARING RELATIONSHIPS WITH DETAINED YOUTH, AS WELL AS SUPERVISION POLICIES AND STRUCTURES THAT PROMOTE SUCH RELATIONSHIPS ON AN ONGOING BASIS.   FOR ALL PARTNERS, JDI AND LMM WILL PROVIDE INDIVIDUALIZED TRAINING AND TECHNICAL ASSISTANCE BASED ON THEIR SPECIFIC NEEDS AND CHALLENGES. JDI AND LMM WILL ALSO SHARE NEW AND EXISTING TOOLS RELATED TO SUPPORTING INCARCERATED YOUTH, AND FACILITATE OPPORTUNITIES FOR ONGOING PEER SHARING TO ENSURE THE LESSONS LEARNED THROUGH THIS PROJECT ARE AVAILABLE TO OTHER JURISDICTIONS SEEKING TO ESTABLISH SERVICES FOR DETAINED YOUTH IN THEIR COMMUNITY.

MIAMI-DADE INMATE SAFETY PROJECT

NO BAD VICTIMS: SUPPORT FOR INCARCERATED SURVIVORS

BUILD TO LAST: DEVELOPING SUSTAINABLE SERVICES FOR INCARCERATED SEXUAL ABUSE SURVIVORS

THE OFFICE ON VIOLENCE AGAINST WOMEN (OVW) TRAINING AND TECHNICAL ASSISTANCE (TA) INITIATIVE PROVIDES OVW GRANTEES AND SUBGRANTEES WITH THE EXPERTISE AND SUPPORT THEY NEED TO DEVELOP AND IMPLEMENT SUCCESSFUL STATE, LOCAL, TRIBAL, AND CAMPUS PROJECTS; INCREASE VICTIM SAFETY; AND BOLSTER OFFENDER ACCOUNTABILITY. THROUGH COOPERATIVE AGREEMENTS, OVW SUPPORTS EDUCATIONAL INITIATIVES, CONFERENCES, PEER-TO-PEER CONSULTATIONS, AND TARGETED ASSISTANCE THAT ALLOW CURRENT AND POTENTIAL GRANTEES AND SUBGRANTEES TO LEARN FROM EXPERTS AND ONE ANOTHER ABOUT HOW TO OVERCOME OBSTACLES AND INCORPORATE PROMISING PRACTICES IN THEIR EFFORTS TO ADDRESS VIOLENCE AGAINST WOMEN. IN ADDITION, OVW IS FOCUSED ON BUILDING THE CAPACITY OF THE CRIMINAL AND CIVIL JUSTICE SYSTEMS AND VICTIM SERVICES PROVIDERS TO RESPOND EFFECTIVELY TO DOMESTIC VIOLENCE, DATING VIOLENCE, SEXUAL ASSAULT, AND STALKING AND TO FOSTER PARTNERSHIPS BETWEEN ORGANIZATIONS THAT HAVE NOT TRADITIONALLY WORKED TOGETHER TO ADDRESS VIOLENCE AGAINST WOMEN.   THIS AWARD WILL SUPPORT FY 2022 TA INITIATIVE PURPOSE AREA 2, TO PROVIDE TRAINING AND TECHNICAL ASSISTANCE TO LOCAL RAPE CRISIS CENTERS, STATE SEXUAL ASSAULT COALITIONS, AND CORRECTIONAL FACILITIES (INCLUDING PRISONS, JAILS, AND JUVENILE DETENTION) TO STRENGTHEN ORGANIZATIONAL EXPERTISE AND BUILD COMMUNITY-BASED PARTNERSHIPS THAT ADDRESS THE UNIQUE NEEDS OF SEXUAL ASSAULT SURVIVORS WHO ARE CURRENTLY OR FORMERLY INCARCERATED. THIS PROJECT WILL ADDRESS HOW SURVIVORS WHO ARE RELEASED CAN BE CONNECTED TO COMMUNITY BASED SEXUAL ASSAULT SERVICES.     THE TIMING FOR PERFORMANCE OF THIS AWARD IS 36 MONTHS.   THIS AWARD IS A CONTINUATION OF 2019-TA-AX-K017.

ATTENTION, INC. BASIC CENTER PROGRAM APPLICATION

GREATER KANSAS CITY CRIME PREVENTION INITIATIVES

LIVE ATTENUATED ORAL TYPHOID-SHIGELLOSIS VACCINE

MULTI-STAGE MULTI-ANTIGEN VACCINE FOR INTERRUPTING MALARIA TRANSMISSION

IMMUNIZING AGAINST MALARIA BY INDUCING BOTH PROTECTIVE ANTIBODIES AND CD8 T CELLS

MULTI-LIGAND MEROZOITE INVASION BLOCKING MALARIA VACCINE

RURAL HEALTH WORKFORCE DEVELOPMENT PROGRAM

TGTHR'S BASIC CENTER PROGRAM AT THE SOURCE

ATTENTION HOMES BASIC CENTER PROGRAM

LEADERSHIP OF VOICES OF EXPERIENCE (LOVE)

CRITTENTON CENTER TRAUMA MHAT FOR YOUTH - PROJECT ABSTRACT SUMMARY PROJECT NAME: CRITTENTON CENTER TRAUMA MHAT FOR YOUTH APPLICANT: FLORENCE CRITTENTON HOME DBA CRITTENTON CENTER PROJECT SUMMARY: THE PURPOSE OF THE PROPOSED TRAINING PROJECT IS TO ENHANCE PARTNERSHIPS AND TRAIN INDIVIDUALS FROM CHILD-FAMILY SERVING SYSTEMS IN WESTERN IOWA TO RECOGNIZE THE SIGNS AND SYMPTOMS OF MENTAL DISORDERS, HOW TO SAFELY DE-ESCALATE CRISIS SITUATIONS INVOLVING INDIVIDUALS WITH A MENTAL ILLNESS AND TO PROVIDE EDUCATION ON RESOURCES AVAILABLE IN THE COMMUNITY FOR YOUTH WITH A MENTAL HEALTH DISORDER. TARGET POPULATION: POPULATION OF FOCUS TRAINED IN MENTAL HEALTH AWARENESS. THE PROPOSED TRAINING PROJECT IS DESIGNED TO SERVE A BROAD BASE OF COMMUNITY AGENCIES AND INDIVIDUALS, INCLUDING CHILD WELFARE, JUVENILE COURT, SCHOOL PERSONNEL, LAW ENFORCEMENT, MEDICAL STAFF, AGENCIES SERVING MILITARY FAMILIES, BEHAVIORAL HEALTH STAFF, FIRST RESPONDERS, AND OTHER COMMUNITY MEMBERS. THE PROJECT INCLUDES ACTIVITIES TO SERVE THE SPECIAL POPULATION OF YOUTH FROM MILITARY FAMILIES AND LESBIAN, GAY, BISEXUAL, TRANSGENDER, QUEER AND INTERSEX (LGTBQI+). POPULATION OF FOCUS IMPACTED BY INDIVIDUALS TRAINED. THE TARGET POPULATION TO BENEFIT FROM THE RESULTS OF THE PROPOSED TRAINING PROJECT ARE CHILDREN AND YOUNG ADULTS AND THEIR FAMILY AND/OR CAREGIVERS WHO ARE AT-RISK FOR MENTAL HEALTH CHALLENGES, MAY BE DEVELOPING OR EXPERIENCING MENTAL HEALTH CHALLENGES, AND/OR WHO MAY BE IN EXPERIENCING A MENTAL HEALTH CRISIS. DEMOGRAPHIC CHARACTERISTICS OF TARGET POPULATION: THE GEOGRAPHIC CATCHMENT AREA IS THE CITY OF SIOUX CITY (85,617), WOODBURY COUNTY, IOWA (105,671) AND FIVE SURROUNDING RURAL COUNTIES: CHEROKEE (11,491), CRAWFORD (16,123), IDA (6,888), MONONA (8,486), AND PLYMOUTH (25,681). (CENSUS ESTIMATES, JULY 2022 FOR COUNTIES AND JULY 2021 FOR CITY). STRATEGIES AND INTERVENTIONS: THE PROJECT AIMS TO IMPROVE THE COORDINATION OF SERVICES FOR INDIVIDUALS AND THEIR FAMILIES WHO ARE EXPERIENCING MENTAL HEALTH DISORDERS, BY ESTABLISHING AND EXPANDING LINKAGES WITH LAW ENFORCEMENT, CHILD WELFARE, JUVENILE JUSTICE, SCHOOLS, AND HEALTH CARE AND OTHER COMMUNITY-BASED CHILD-FAMILY SERVING SYSTEMS AND AGENCIES. EVIDENCE-BASED STRATEGIES AND INTERVENTIONS: MENTAL HEALTH FIRST AID (MHFA) FOR YOUTH AND QUESTION, PERSUADE, REFER (QPR) SUICIDE PREVENTION GATEKEEPER TRAINING. PROJECT GOALS: GOAL I: TO CREATE THE ORGANIZATIONAL CAPACITY TO IMPLEMENT AND SUSTAIN GRANT ACTIVITIES, ENSURING THE REQUIRED ELEMENTS OF THE GRANT ARE DELIVERED ON TIME AND AS INTENDED, BY REINFORCING COMMUNITY PARTNERSHIPS. GOAL II: TO OFFER EXPANDED ACCESS TO TWO EVIDENCE-BASED MENTAL HEALTH AWARENESS TRAINING PROGRAMS TARGETING YOUTH MENTAL HEALTH BY PROMOTING AND OFFERING THESE TRAININGS WITH COMMUNITY YOUTH-SERVING AGENCIES, INCLUDING LAW ENFORCEMENT, EDUCATION, CHILD WELFARE, JUVENILE JUSTICE, AND HEALTH CARE: MENTAL HEALTH FIRST AID (MHFA) AND QUESTION, PERSUADE, REFER (QPR). GOAL III: TO IMPROVE COLLABORATION AND LINKAGES AMONG COMMUNITY AGENCIES TO PROMOTE UNDERSTANDING, CREATE SENSITIVITY, AND ENHANCE REFERRAL PROCESSES FOR ACCESSING MENTAL HEALTH SERVICES AND RESOURCES FOR YOUTH AT-RISK OF OR EXPERIENCING MENTAL HEALTH DISORDERS. NUMBER TO BE SERVED ANNUALLY AND THROUGHOUT LIFETIME OF PROJECT: THE PROJECT PROPOSES TO OFFER 32 EBP TRAININGS (YEAR 1: 8, YEAR 2: 12, YEAR 3: 12); TRAIN 320 INDIVIDUALS (YEAR 1: 80, YEAR 2: 120, YEAR 3: 120); REFER A MINIMUM OF 160 INDIVIDUALS TO MENTAL HEALTH OR RELATED SERVICES (YEAR 1: 40, YEAR 2: 60, YEAR 3: 60); AND HOST FOUR COMMUNITY OUTREACH EVENTS ANNUALLY FOR A TOTAL OF 12 EVENTS, TARGETING 15 INDIVIDUALS PER EVENT OR 60 INDIVIDUALS ANNUALLY OR 180 FOR THE PROJECT PERIOD.

LIVE ATTENUATED ORAL ANTHRAX VACCINE

RECOMBINANT PLASODIUM FALCIPARUM CELTOS VACCINE

FIELD INITIATED PROJECTS PROGRAM: INCREASING COMMUNITY PARTICIPATION AMONG ADULTS WITH PSYCHIATRIC DISABILITIES THROUGH INTENTIONAL PEER SUPPORT

MULTIVALENT ORAL VACCINE AGAINST ENTEROTOXIGENIC ESCHERICHIA COLI AND ENTERIC FEVERS

"EXTREMELY HIGH-PERFORMANCE ULTRA-LOW POWER RADIATION-TOLERANT PROCESSOR: AN ENABLING TECHNOLOGY F

BEYOND THE BASICS: MEETING THE NEEDS OF INCARCERATED SEXUAL ABUSE SURVIVORS

YOUTH-DRIVEN CONFLICT PREVENTION IN NORTHERN BORDER ZONE

BRAZIL -FISH OF CHANGE

SBIR PHASE II: COLLABORATIVE PATENT DRAFTING SOFTWARE

NOVEL REPROGRAMMED CELLS FOR DIFFERENTIATION INTO CARDIOMYOCYTES

2019 HPF SAT - EASTERN STATE PENITENTIARY HISTORIC SITE

GREATER KANSAS CITY CRIME PREVENTION INITIATIVES

LOMAS COMMUNITY PREVENTION COALITION.

RENEWABLENY - AN INDUSTRIAL ENERGY CONSERVATION INITATIVE

SUPPORTIVE HOUSING PROGRAM

ATTENTION HOMES STREET OUTREACH PROGRAM FOR RUNAWAY, AT-RISK AND HOMELESS YOUTH

ADDRESSING UNMET NEEDS RELATED TO CORONAVIRUS EXPENSES

IMPROVED RATIOMETRIC VOLTAGE-SENSITIVE DYES FOR IN-VITRO AND IN-VIVO IMAGING OF BRAIN ELECTRICAL SIGNALING

TGTHR STREET OUTREACH PROGRAM

NATIONAL SEXUAL VIOLENCE IN DETENTION EDUCATION AND RESOURCE PROJECT

WASTE DISPOSAL GRANTS - REGULAR

STREET OUTREACH PROGRAM

NEW VENTURES WILL DEVELOP AN INNOVATIVE, FOUNDER-FRIENDLY INVESTMENT VEHICLE ABLE TO PROVIDE REVENUE-BASED SEED INVESTMENTS TO EARLY-STAGE SOCIAL, ENVIRONMENTAL AND WOMEN LED COMPANIES.

STUDY OF THE USE OF RESIDENTIAL SUBSTANCE ABUSE TREATMENT FOR STATE PRISONERS PROGRAM FUNDS ON AFTERCARE SERVICES

PURPOSE: THE YOUTH HOMELESSNESS DEMONSTRATION PROGRAM (YHDP) AIMS TO SUPPORT SELECTED COMMUNITIES IN DEVELOPING AND IMPLEMENTING A COORDINATED COMMUNITY APPROACH TO PREVENTING AND ENDING YOUTH HOMELESSNESS. THE POPULATION TO BE SERVED BY THIS DEMONSTRATION PROGRAM IS YOUTH EXPERIENCING HOMELESSNESS, INCLUDING UNACCOMPANIED AND PREGNANT OR PARENTING YOUTH. THE DEMONSTRATION HAS SEVEN PRIMARY OBJECTIVES: • BUILD NATIONAL MOMENTUM. • PROMOTE EQUITY IN THE DELIVERY AND OUTCOMES OF HOMELESS ASSISTANCE. • HIGHLIGHT THE IMPORTANCE OF YOUTH LEADERSHIP. • EVALUATE THE COORDINATED COMMUNITY APPROACH. • EXPAND CAPACITY. • EVALUATE PERFORMANCE MEASURES. • ESTABLISH A FRAMEWORK FOR THE FEDERAL PROGRAM AND TECHNICAL ASSISTANCE COLLABORATION. BEGINNING IN 2016, NEW YHDP COMMUNITIES ARE SELECTED THROUGH A COMPETITIVE PROCESS DEPENDING ON THE ANNUAL FUNDING PROVIDED BY CONGRESS. A MAP OF CURRENTLY FUNDED YHDP SITES IS AVAILABLE AT THE LINK TITLED MAP OF YHDP-FUNDED COC (UNDER YHDP COMMUNITIES) AT HTTPS://WWW.HUDEXCHANGE.INFO/PROGRAMS/YHDP/.; ACTIVITIES TO BE PERFORMED: ELEVEN TYPES OF ASSISTANCE MAY BE PROVIDED THROUGH THE YHDP: 1. ACQUISITION OF REAL PROPERTY (INCLUDING STRUCTURES) FOR USE IN THE PROVISION OF HOUSING OR SUPPORTIVE SERVICES; 2. REHABILITATION OF STRUCTURES TO PROVIDE HOUSING OR SUPPORTIVE SERVICES; 3. NEW CONSTRUCTION, INCLUDING THE BUILDING OF A NEW STRUCTURE OR BUILDING AN ADDITION TO AN EXISTING STRUCTURE FOR USE AS SUPPORTIVE HOUSING; 4. LEASING OF A NEW STRUCTURE OR STRUCTURES, OR PORTIONS THEREOF, TO PROVIDE HOUSING OR SUPPORTIVE SERVICES; 5. RENTAL ASSISTANCE, WHICH MAY BE SHORT-TERM, MEDIUM-TERM, OR LONG-TERM, AS WELL AS TENANT-BASED, PROJECT-BASED, OR SPONSOR-BASED, FOR TRANSITIONAL OR PERMANENT HOUSING; 6. SUPPORTIVE SERVICES TO ASSIST PROGRAM PARTICIPANTS OBTAIN AND MAINTAIN HOUSING; 7. OPERATING COSTS OF SUPPORTIVE HOUSING; 8. COSTS OF IMPLEMENTING AND OPERATING HOMELESS MANAGEMENT INFORMATION SYSTEM (HMIS); 9. PROGRAM ADMINISTRATIVE COSTS; 10. RELOCATION COSTS; AND 11. INDIRECT COSTS IN ACCORDANCE WITH 2 CFR PART 200, AS APPLICABLE. NO ASSISTANCE PROVIDED UNDER THIS PROGRAM (OR ANY STATE OR LOCAL GOVERNMENT FUNDS USED TO SUPPLEMENT THIS ASSISTANCE) MAY BE USED TO REPLACE STATE OR LOCAL FUNDS PREVIOUSLY USED, OR DESIGNATED FOR USE, TO ASSIST HOMELESS PERSONS OR PERSONS AT-RISK OF HOMELESSNESS.; EXPECTED OUTCOMES: AS A RESULT OF DEVELOPING AND IMPLEMENTING A COORDINATED COMMUNITY APPROACH TO PREVENTING AND ENDING YOUTH HOMELESSNESS, THERE WILL BE: • SIGNIFICANT DECREASE IN THE NUMBER OF YOUTH EXPERIENCING HOMELESSNESS. • INCREASED INCOME, EDUCATION, HEALTH, AND SOCIAL/EMOTIONAL WELL-BEING OF PARTICIPANTS. • COMMUNITY-LEVEL UNDERSTANDING OF THE NUMBER AND NEEDS OF YOUTH AT-RISK OF AND EXPERIENCING HOMELESSNESS. • NEW OR IMPROVED PARTNERSHIPS BETWEEN YOUTH-SERVING ORGANIZATIONS IN THE COMMUNITY.; INTENDED BENEFICIARIES: HOMELESS UNACCOMPANIED YOUTH (AGE 24 AND YOUNGER) AND HOMELESS YOUTH (AGE 24 AND YOUNGER) WITH CHILDREN.; SUBRECIPIENT ACTIVITIES: THE SUBRECIPIENT ACTIVITIES ARE UNKNOWN AT THE TIME OF AWARD.

KEOKUK IOWA DRUG FREE COMMUNITY SUPPORT PROGRAM

CRITTENTON CENTER - BASIC CENTER PROGRAM "THE MOBILE MANSION: OUTREACH IN MOTION" - THE BASIC CENTER PROGRAM (BCP) (CY) PROVIDES TEMPORARY SHELTER AND COUNSELING SERVICES TO YOUTH WHO HAVE LEFT HOME WITHOUT PERMISSION OF THEIR PARENTS OR GUARDIANS, HAVE BEEN FORCED TO LEAVE HOME, OR OTHER HOMELESS YOUTH WHO MIGHT OTHERWISE END UP IN THE LAW ENFORCEMENT OR IN THE CHILD WELFARE, MENTAL HEALTH, OR JUVENILE JUSTICE SYSTEMS. BCPS WORK TO ESTABLISH OR STRENGTHEN COMMUNITY-BASED PROGRAMS THAT MEET THE IMMEDIATE NEEDS OF RUNAWAY AND HOMELESS YOUTH AND THEIR FAMILIES. BCPS PROVIDE YOUTH UNDER 18 YEARS OF AGE WITH EMERGENCY SHELTER, FOOD, CLOTHING, COUNSELING AND REFERRALS FOR HEALTH CARE. BCPS CAN PROVIDE UP TO 21 DAYS OF SHELTER FOR YOUTH AND SEEK TO REUNITE YOUNG PEOPLE WITH THEIR FAMILIES, WHENEVER POSSIBLE, OR TO LOCATE APPROPRIATE ALTERNATIVE PLACEMENTS.

TGTHR TRANSITIONAL LIVING PROGRAM - THE TRANSITIONAL LIVING PROGRAM (TLP) (CX) PROVIDES SAFE, STABLE, AND APPROPRIATE SHELTER FOR RUNAWAY AND HOMELESS YOUTH AGES 16 TO UNDER 22 FOR UP TO 18 MONTHS AND, UNDER EXTENUATING CIRCUMSTANCES, CAN BE EXTENDED TO 21 MONTHS. TLPS PROVIDE COMPREHENSIVE SERVICES (E.G., BASIC LIFE SKILLS, EDUCATIONAL AND JOB ATTAINMENT OPPORTUNITIES, COUNSELING) THAT SUPPORTS THE TRANSITION OF HOMELESS YOUTH TO SELF-SUFFICIENCY AND STABLE, INDEPENDENT LIVING.

THE CENTRAL FALLS DETENTION FACILITY CORPORATION PROPOSES TO IMPLEMENT PROJECT DEEP: DIGITAL EVIDENCE TO ENHANCE PRACTICES. THE PURPOSE OF THE PROJECT IS TO EXPAND AND ENHANCE THE CURRENT BODY-WORN CAMERA PROGRAM AT THE FACILITY AND REBUILD ITS DIGITAL EVIDENCE MANAGEMENT TO ACHIEVE FURTHER IMPROVEMENTS IN EMPLOYEE PERFORMANCE, CONSTITUTIONAL POLICING, AND FACILITY/COMMUNITY SAFETY PRACTICES. THE DESIGN OF THE PROJECT WILL TAKE A RESEARCH-TO-PRACTICE APPROACH BY ANALYZING EVIDENCE TO DEVELOP POLICY, PROCEDURE, AND TRAINING RECOMMENDATIONS AS THE FOUNDATION FOR CONTINUAL PROCESS IMPROVEMENTS TO THE OPERATIONAL ENVIRONMENT. THE FIRST GOAL OF PROJECT DEEP WILL BE TO (1) UPGRADE THE FACILITYS BWC EQUIPMENT TO ENHANCE QUALITY, RELIABILITY, EFFICIENCY, AND UTILITY OF AVAILABLE EVIDENCE AND EXPAND USE OF BWCS TO NEW CATEGORIES OF EMPLOYEES. THE SECOND GOAL OF THE PROJECT IS TO LEVERAGE AN UPGRADED AND EXPANDED BODY-WORN CAMERA PROGRAM TO (2) FURTHER DEVELOP AND ENHANCE DIGITAL EVIDENCE MANAGEMENT AND EMPLOYEE PERFORMANCE AND TRAINING PRACTICES. THE PROJECT WILL ESTABLISH A STAKEHOLDER ADVISORY GROUP TO INFORM THE PRACTICE AREA OF DIGITAL EVIDENCE MANAGEMENT REGARDING PROCEDURES FOR INTEGRATING DIGITAL EVIDENCE SHARING ACTIVITIES WITH CRIMINAL JUSTICE PARTNERS. THE PROJECT WILL ALSO ESTABLISH AN EVIDENCE REVIEW TEAM TO INFORM THE PRACTICE AREA OF EMPLOYEE PERFORMANCE AND TRAINING BY EVALUATING DE-ESCALATION AND POLICY COMPLIANCE SCENARIOS. EVIDENCE GENERATED FROM THE SCENARIOS OR OTHER INCIDENTS WILL BE INTEGRATED AND UTILIZED AS TRAINING TOOLS FOR CURRENT EMPLOYEE AND ACADEMY TRAININGS. PROJECT DEEP EXPECTS THE OUTCOMES OF INCREASED QUALITY, RELIABILITY, EFFICIENCY, AND UTILIZATION OF DIGITAL EVIDENCE; IMPROVED DIGITAL EVIDENCE MANAGEMENT; OPTIMIZED AVAILABILITY OF DIGITAL EVIDENCE TO ACHIEVE JUST LEGAL OUTCOMES; ENHANCED TRAINING TOOLS FOR EMPLOYEES RESULTING IN IMPROVED EMPLOYEE PERFORMANCE METRICS; INCREASED SUCCESS RATES OF DE-ESCALATIONS; AND A DECREASE IN DEVIATIONS FROM BODY-WORN CAMERA PROGRAM POLICY AND PROCEDURES. ACHIEVING THESE OUTCOMES WILL RESULT IN INCREASED EQUITY, SAFETY, AND TRANSPARENCY FOR DETAINEES AND EMPLOYEES, AS WELL AS EVIDENTIARY SUPPORT FOR PROSECUTORS AND THE OVERALL FACILITY COMMUNITY. SUBRECIPIENT ACTIVITIES WILL INCLUDE TRAIN-THE-TRAINER TECHNICAL ASSISTANCE REGARDING NEW EQUIPMENT AND ESTABLISHING DATA COLLECTION PROTOCOLS AS WELL AS DISSEMINATION OF BEST PRACTICES TO THE GRANTS TRAINING AND TECHNICAL ASSISTANCE PROVIDER, AND PROCUREMENT OF NEW EQUIPMENT.

HAG TECHNICAL ASSISTANCE

IN EL SALVADOR, ONE OF THE MOST WATER-STRESSED COUNTRIES IN CENTRAL AMERICA, LOCAL WATER BOARDS PLAY A CRITICAL ROLE IN CONSERVING THIS CRITICAL RESOURCE AND MANAGING COMMUNITIES? ACCESS TO WATER. THE IAF SUPPORTS COMMUNITY-LED SOLUTIONS TO STRENGTHEN GOVERNANCE OF NEEDED NATURAL RESOURCES, ADDRESSING FACTORS DRIVING MIGRATION OUT OF CENTRAL AMERICA. IAF GRANTEE THE CENTRO DE ESTUDIOS APLICADOS EN ECOLOGÍA Y SUSTENTABILIDAD AMBIENTAL (ECOS) IS PROVIDING TRAINING AND TECHNICAL ASSISTANCE TO MEMBERS OF THE ASSOCIATION OF WATER BOARDS,  AS WELL AS 25 LOCAL WATER BOARDS TO IMPROVE WATER MANAGEMENT IN THE MUNICIPALITIES OF LIBERTAD CENTRO AND LIBERTAD NORTE IN THE DEPARTMENT OF LA LIBERTAD, EL SALVADOR.  THIS GRANT IS PART OF THE IAF'S EFFORTS TO ADDRESS THE ROOT CAUSES OF IRREGULAR MIGRATION IN CENTRAL AMERICA.

ASSISTANCE TO FIREFIGHTERS GRANT

IMPROVING EPIGENETIC-BASED CELL REPROGRAMMING WITH PROTEASOME INHIBITION

DEVELOPMENT OF A HUMAN OCT-4 GENE-TARGETED REPORTER CELL LINE

AN EXPLORATORY STUDY OF JUVENILE ORDERS OF PROTECTION AS A REMEDY TO DATING VIOLENCE

HOMELESS VETERANS (HVRP)

CRITTENTON CENTER STREET OUTREACH PROJECT (SOP)

TGTHR STREET OUTREACH PROGRAM

THIS ACTIVITY AIMS TO INCREASE THE RESILIENCY OF MOLDOVAN CIVIL SOCIETY BY ENHANCING THE ABILITY OF CIVIL SOCIETY ORGANIZATIONS (CSOS) TO ENGAGE WITH CONSTITUENTS AND DIVERSIFY THEIR RESOURCE BASE. THE ACTIVITY WILL BROADLY DEFINE CIVIL SOCIETY TO INCLUDE NOT ONLY WELL-ESTABLISHED, REGISTERED CSOS BUT ALSO UNREGISTERED CIVIC GROUPS, ISSUES-BASED GROUPS AND CIVIC MOVEMENTS.

GREEN MANUFACTURING TA

BIODEGRADABILITY AND BIOCOMPATIBILITY OF A SHAPE MEMORY POLYMER WRAP TO IMPROVE SAPHENOUS VEIN GRAFT PATENCY IN PERIPHERAL AND CORONARY ARTERY BYPASS GRAFTING SURGERIES

GREATER KANSAS CITY METROPOLITAN CRIME PREVENTION INITIATIVES

MYDOCSAID: DEEP LEARNING FOR PATIENT-CENTRIC RECORD, SUMMARIZATION, AND ANALYSIS OF MEDICAL CONVERSATIONS - ABSTRACT PATIENTS RETAIN AND RECALL LESS THAN 10% OF MEDICAL CARE PLANS CORRECTLY AFTER 5 TO 7 DAYS LEADING DIRECTLY TO POOR COMPREHENSION, ENGAGEMENT, COMPLIANCE, AND POOR HEALTH OUTCOMES. THIS PERVASIVE AND DETRIMENTAL DYNAMIC IS A SIGNIFICANT CONTRIBUTOR TO LARGE WASTE IN THE ANNUAL US HEALTHCARE SPENDING NOW EXCEEDING $4 TRILLION WITH A CONSERVATIVE ESTIMATE OF 25% OR $1 TRILLION ANNUALLY. ON THE OTHER HAND, PATIENTS OFTEN FIND MANAGING THEIR HEALTHCARE OVERWHELMING WITH COMPLEX/MULTIPLE DIAGNOSES, SPECIALISTS, AND MEDICATIONS PRESCRIBED BY DIFFERENT PROVIDERS WITH A HIGHER IMPACT ON OLDER ADULTS. TYPICALLY PROVIDER VISITS FREQUENTLY INCREASE WITH AGE. FOR A VARIETY OF REASONS, AGING PATIENTS GENERALLY EXPERIENCE AN INCREASINGLY DIFFICULT TIME REMEMBERING AND UNDERSTANDING THE DETAILS OF WHAT WAS DISCUSSED DURING THEIR OFFICE VISITS. ADULT CHILDREN OF AGING PATIENTS OFTEN ASSIST AND PARTICIPATE IN THEIR PARENT’S MEDICAL CARE BUT OFTEN CAN’T ACCOMPANY THEM TO PROVIDER VISITS. UNFORTUNATELY, EXISTING TECHNOLOGY FALLS SHORT OF MEETING THESE PATIENTS’ NEEDS. ALMOST ALL EXISTING HEALTH RECORDING TOOLS ARE PROVIDER-CENTRIC AND NONE ARE TRULY AND COMPLETELY PATIENT-CENTRIC ALLOWING PATIENTS TO RECORD PROVIDER INTERACTIONS WITH NATURAL LANGUAGE PROCESSING (NLP) TRANSLATION, SEARCHABILITY ALONG WITH FULL PATIENT CONTROL, DATA MOBILITY, EDUCATION, AND REAL-TIME ARTIFICIAL INTELLIGENCE (AI) SUPPORT. POTENTIA ANALYTICS INC. PROPOSES THE DEVELOPMENT OF ITS PATIENT-CENTRIC HEALTH RECORDER APP, CALLED MYDOCSAID, TO ADDRESS THESE ISSUES. MYDOCSAID WILL BE DESIGNED TO PROVIDE PATIENTS WITH A SECURE, FAST, SEARCHABLE, AND EXTREMELY USER-FRIENDLY TECHNOLOGY ENHANCING PATIENT RECALL, REMEMBERING, COMPREHENSION, AND ENGAGEMENT IN THEIR OWN HEALTH MAINTENANCE OR RESTORATION. THIS TECHNOLOGY PLATFORM WILL ALSO PLAY A PIVOTAL ROLE IN ADVANCING THE DYNAMIC OF “SHARED DECISION-MAKING”. AT-RISK POPULATIONS LIKE SENIOR CITIZENS COULD BENEFIT FROM THE MYDOCSAID APPLICATION. PRELIMINARY STUDIES AT POTENTIA ANALYTICS SHOW THAT THE STATE-OF-THE-ART AUTOMATIC SPEECH RECOGNITION (ASR) AND NLP MODELS WILL BE ABLE TO SOLVE THIS PROBLEM AND PROVIDE TRANSCRIPTION, SUMMARY, AND KEYWORDS FROM MEDICAL CONVERSATIONS. TO DEVELOP THE BACK-END AND AI COMPONENTS, POTENTIA ANALYTICS WILL USE TRANSFER LEARNING TO FINE-TUNE LANGUAGE MODELS FOR MEDICAL CONVERSATIONS. DEMONSTRATING FEASIBILITY IN PHASE I REQUIRES A WORKING AI PIPELINE (INCLUDING ASR/NLP MODELS AND KNOWLEDGE GRAPHS (KG)) THAT CAN PASS USABILITY TESTS IN A PRODUCTION ENVIRONMENT. THE SPECIFIC AIMS TO ACCOMPLISH THIS GOAL ARE: 1) TRAIN AND IMPLEMENT DEEP LEARNING MODELS FOR ASR & NLP TASKS. 2) TRAIN/IMPLEMENT KGS AND DEEP LEARNING MODELS TO RECOGNIZE MEDICAL NAMED ENTITIES AND THEIR RELATIONSHIPS. 3) INTEGRATE THE DATA/AI PIPELINE. MEDICAL TERMINOLOGIES WILL BE DETECTED USING KNOWLEDGE GRAPHS (KG) TRAINED ON MEDICAL ONTOLOGIES AND WILL PROVIDE INFORMATION ABOUT THE CONTEXT OF THE MEDICAL CONVERSATIONS. THE FINE-TUNED AI MODELS AND KNOWLEDGE GRAPHS CAN BE USED BY OTHER RESEARCHERS TO FURTHER ADVANCE NLP IN THE MEDICAL CONTEXT AND ONTOLOGIES. THE FRONT-END ALGORITHMS AND THE USER INTERFACE WILL BE DESIGNED FOR SEAMLESS USE BY ELDERLY PATIENTS.

A PALETTE OF NEAR-INFRARED VOLTAGE SENSORS FOR CARDIAC RESEARCH AND SAFETY PHARMACOLOGY - PROJECT SUMMARY/ABSTRACT POTENTIOMETRIC PROBES THE OVERALL GOAL OF THIS PHASE I SBIR PROJECT IS TO EXPAND THE CAPABILITIES OF TOOLS, INVENTED BY THE FOUNDERS OF POTENTIOMETRIC PROBE, LLC, FOR HIGH-FIDELITY OPTICAL RECORDING OF ELECTRICAL ACTIVITY IN CARDIAC CELLS, TISSUES, AND WHOLE HEARTS. POTENTIOMETRIC PROBES DEVELOPS ORGANIC VOLTAGE-SENSITIVE DYES (VSDS) THAT CONVERT THE CHANGES IN VOLTAGE ACROSS CELL MEMBRANES TO VISIBLE CHANGES IN FLUORESCENCE. INSTEAD OF INDIVIDUAL ELECTRODES, THIS TECHNOLOGY ENABLES THE USE OF SENSITIVE HIGH-SPEED CAMERAS, WHERE EACH PIXEL CAN BE CONSIDERED AN ELECTRODE, FOR MASSIVELY PARALLEL HIGH THROUGHPUT SCREENING, OR FOR HIGH-RESOLUTION SPATIOTEMPORAL MAPS OF ELECTRICAL SIGNAL PROPAGATION. IMPORTANTLY, OUR VSDS ARE UNIQUE IN ENABLING DUAL-WAVELENGTH RATIOMETRIC RECORDING OF ELECTRICAL ACTIVITY; THIS IS PARTICULARLY IMPORTANT FOR CARDIAC STUDIES BECAUSE IT ELIMINATES CONTRACTION-INDUCED MOTION ARTIFACTS, PERMITTING HIGH-FIDELITY RECORDS OF THE ACTION POTENTIAL WAVEFORM. HUMAN STEM CELL-DERIVED CARDIOMYOCYTES (HIPSC-CMS) ARE HUMAN SKIN OR OTHER CELLS THAT ARE “REPROGRAMMED” TO BE BEATING HEART CELLS IN A DISH. THESE HUMAN CELLS AND THE TISSUES DERIVED FROM THEM ARE INCREASINGLY BEING USED FOR RESEARCH AND DEVELOPMENT PURPOSES, INCLUDING SCREENING NEW DRUGS FOR CARDIOTOXICITY, AND IN THE FUTURE MAY BE USED FOR “PERSONALIZED MEDICINE” AND THE ANALYSIS OF PATIENT-DERIVED CELLS. WE BELIEVE HIGH THROUGHPUT RECORDING OF ACCURATE ACTION POTENTIAL WAVEFORMS FROM HIPSC-CMS AND TISSUES WILL BE A MAJOR MARKET FOR THE PROPOSED TECHNOLOGY. WHILE THESE CELLS BEAT SPONTANEOUSLY, PACING OR STIMULATING THESE CELLS TO BEAT AT SPECIFIC FREQUENCIES IS A CRITICAL PART OF SCREENING PROTOCOLS BECAUSE ELECTRICAL ACTIVITY AND THE CONTRIBUTION OF SPECIFIC ION CHANNELS IS HIGHLY DEPENDENT ON BEAT FREQUENCY. THIS EXTERNAL STIMULATION CAN BE APPLIED USING LIGHT AND RESEARCHERS HAVE INCORPORATED LIGHT-DEPENDENT CHANNEL RHODOPSINS TO CONVENIENTLY ACHIEVE THE DESIRED PACING. HOWEVER, IT IS CRUCIAL TO SEPARATE THE SPECTRA OF LIGHT USED FOR OPTICAL VOLTAGE IMAGING AND STIMULATION. PRELIMINARY WORK SHOWS THAT A NEW CHROMOPHORE DEVELOPED AT OUR COMPANY CAN EXTEND THE WAVELENGTH OF OUR VSDS TO THE NEAR-INFRARED AND ALLOW THEM TO BE USED TO THEIR FULL POTENTIAL, INCLUDING RATIOMETRIC IMAGING, IN CONCERT WITH CHANNEL RHODOPSINS FOR PACING. IN THIS PROPOSAL, POTENTIOMETRIC PROBES WILL SYNTHESIZE A SET OF NEAR-INFRARED VSDS AND WILL CHARACTERIZE THEIR PERFORMANCE IN CELLS INCLUDING HIPSC-CMS. ULTIMATELY, THE TECHNOLOGY MAY ALLOW MUCH GREATER FLEXIBILITY TO RESEARCHERS, ENABLE MULTIPLEXED IMAGING EXPERIMENTS NOT PREVIOUSLY POSSIBLE, AND IN THE FUTURE MAY ALSO BE APPLIED CLINICALLY FOR HIGH-RESOLUTION IMAGING OF ACTION POTENTIAL PROPAGATION IN THE HEART.

MULTI-COUNTY JUVENILE ATTENTION CENTER PROJECT

THE OFFICE ON VIOLENCE AGAINST WOMEN (OVW) TRAINING AND TECHNICAL ASSISTANCE (TA) INITIATIVE PROVIDES OVW GRANTEES AND SUBGRANTEES WITH THE EXPERTISE AND SUPPORT THEY NEED TO DEVELOP AND IMPLEMENT SUCCESSFUL STATE, LOCAL, TRIBAL, AND CAMPUS PROJECTS; INCREASE VICTIM SAFETY; AND BOLSTER OFFENDER ACCOUNTABILITY. THROUGH COOPERATIVE AGREEMENTS, OVW SUPPORTS EDUCATIONAL INITIATIVES, CONFERENCES, PEER-TO-PEER CONSULTATIONS, AND TARGETED ASSISTANCE THAT ALLOW CURRENT AND POTENTIAL GRANTEES AND SUBGRANTEES TO LEARN FROM EXPERTS AND ONE ANOTHER ABOUT HOW TO OVERCOME OBSTACLES AND INCORPORATE PROMISING PRACTICES IN THEIR EFFORTS TO ADDRESS VIOLENCE AGAINST WOMEN. IN ADDITION, OVW IS FOCUSED ON BUILDING THE CAPACITY OF THE CRIMINAL AND CIVIL JUSTICE SYSTEMS AND VICTIM SERVICE PROVIDERS TO RESPOND EFFECTIVELY TO DOMESTIC VIOLENCE, DATING VIOLENCE, SEXUAL ASSAULT, AND STALKING AND TO FOSTER PARTNERSHIPS BETWEEN ORGANIZATIONS THAT HAVE NOT TRADITIONALLY WORKED TOGETHER TO ADDRESS VIOLENCE AGAINST WOMEN. WITH FY 2024 TA INITIATIVE FUNDING, JUST DETENTION INTERNATIONAL, INC. (JDI) WILL IMPLEMENT ITS ALIGNING VISIONS: ADAPTING THE NATIONAL PROTOCOL FOR SEXUAL ASSAULT MEDICAL FORENSIC EXAMINATIONS TO MEET THE NEEDS OF INCARCERATED SURVIVORS PROJECT. THIS PROJECT WILL PROVIDE RECOMMENDATIONS FOR UPDATING OVWS 2013 RECOMMENDATIONS FOR ADMINISTRATORS OF PRISONS, JAILS, AND COMMUNITY CONFINEMENT FACILITIES FOR ADAPTING THE U.S. DEPARTMENT OF JUSTICES A NATIONAL PROTOCOL FOR SEXUAL ASSAULT MEDICAL FORENSIC EXAMINATIONS, ADULTS/ADOLESCENTS. OVER THE COURSE OF THE PROJECT PERIOD, JDI WILL CONDUCT AN INITIAL REVIEW OF THE 2013 RECOMMENDATIONS, HOLD GROUP DISCUSSIONS AND INTERVIEWS WITH SUBJECT MATTER EXPERTS, IDENTIFY AND GATHER RELEVANT SUPPLEMENTAL RESOURCES AND MATERIALS, AND DEVELOP A DRAFT AND FINAL OUTLINE FOR THE UPDATED RECOMMENDATIONS. THIS PROJECT SUPPORTS FY 2024 TA INITIATIVE PURPOSE AREA 22: UPDATE TO RECOMMENDATIONS FOR ADMINISTRATORS OF PRISONS, JAILS, AND COMMUNITY CONFINEMENT FACILITIES FOR ADAPTING THE U.S. DEPARTMENT OF JUSTICES A NATIONAL PROTOCOL FOR SEXUAL ASSAULT MEDICAL FORENSIC EXAMINATIONS, ADULTS/ADOLESCENTS. THE TIMING FOR PERFORMANCE OF THIS AWARD IS 24 MONTHS. THIS IS A NEW AWARD.

STTR PHASE I: ASSISTED INVENTION DISCLOSURE TOOL

FARMERS ARE OFTEN ABSENT FROM DISCUSSIONS ABOUT HOW POLICIES AND PROGRAMS IMPACT SUSTAINABLE AGRICULTURAL PRODUCTION. AT THE IAF, WE ARE INVESTING IN A REGIONAL EFFORT, IN CONJUNCTION WITH THE UNIVERSITY OF BRITISH COLUMBIA, THAT WILL GIVE VOICE TO FARMERS AND DIRECTLY SUPPORT THEM IN COLLECTING, ANALYZING, AND PRESENTING DATA THAT THEY CAN INCORPORATE INTO THEIR OPERATIONS TO MANAGE THEIR FARMS MORE EFFICIENTLY. CENTRO CAMPESINO PARA EL DESARROLLO SUSTENTABLE, A.C. (CAMPESINO) ESTABLISHED MEXICO’S FIRST RECOGNIZED PARTICIPATORY CERTIFICATION SYSTEM AND THE FIRST NETWORK CONNECTING PRODUCERS DIRECTLY TO CONSUMERS TO IMPROVE FARMERS’ QUALITY OF LIFE AND CONSUMERS’ FOOD SECURITY. IT PROVIDES TRAINING AND TECHNICAL ASSISTANCE PROGRAMS THAT EMPHASIZE REVITALIZING TRADITIONAL KNOWLEDGE AND FARM PRACTICES THAT PROTECT THE ENVIRONMENT AND PROMOTE SUSTAINABLE AGRICULTURAL TECHNOLOGIES. THE RESULTS OF THIS REGIONAL PROJECT WILL INFORM AGRICULTURAL SUPPORT ORGANIZATIONS, GOVERNMENT EXTENSION EXPERTS, FARMER GROUPS, AND POLICY-MAKERS WITH CONTEXT-SPECIFIC DATA ABOUT HOW TO ENCOURAGE THE TRANSITION TO SUSTAINABLE AGRICULTURAL PRACTICES TO IMPROVE FOOD SECURITY, ENHANCE FARMER LIVELIHOODS, AND MINIMIZE ENVIRONMENTAL DEGRADATION. THIS IS PART OF THE IAF’S STRATEGIC INITIATIVE FOR SUSTAINABLE AGRICULTURE.

A NOVEL AGENT FOR PREVENTING FATTY DEGENERATION OF MUSCLES IN LGMD2B - ABSTRACT MUSCULAR DYSTROPHIES ARE GRAVE GENETIC DISORDERS CHARACTERIZED BY MUSCLE WASTING AND PROGRESSIVE LOSS OF MUSCLE FUNCTION. APPROXIMATELY 250,000 INDIVIDUALS ARE CURRENTLY AFFECTED BY SOME FORM OF MD IN THE US. ALTHOUGH MDS ARE CAUSED BY MUTATIONS IN DIFFERENT GENES, THE MUSCLE PATHOLOGIES PATIENTS DEVELOP ARE SHARED AND MANIFEST AS MUSCLE FATTY DEGENERATION (FD) THROUGH REPLACEMENT OF NECROTIC MUSCLE FIBERS BY ADIPOSE AND FIBROTIC TISSUE LEADING TO LOSS OF MUSCLE FUNCTION. LIMB GIRDLE MUSCULAR DYSTROPHY 2B (LGMD2B) AFFECTS SHOULDER AND HIP MUSCLES, AND RESULTS IN SEVERE FUNCTIONAL DISABILITY BY A PATIENT'S SECOND OR THIRD DECADE. THERE IS CURRENTLY NO CURE OR THERAPY FOR LGMD2B SINCE GLUCOCORTICOIDS, WHICH ARE THE STANDARD-OF-CARE FOR SOME TYPES OF MD, ARE NOT ADVISED FOR LGMD2B. GENE EDITING AND REPLACEMENT THERAPIES ARE BEING DEVELOPED BUT FACE SIGNIFICANT HURDLES CONCERNING EFFICACY AND SAFETY. WE PROPOSE TO DEVELOP ADVERTENT BIOTHERAPEUTICS' PROPRIETARY AGENT ADA011, A SPECIFIC TGF-SS1/3 INHIBITOR, INTO A THERAPY THAT INHIBITS MUSCLE FD AND PRESERVES MUSCLE FUNCTION IN LGMD2B PATIENTS. WE HYPOTHESIZE THAT THIS COULD HELP DELAY THE ONSET OF SYMPTOMS, AMELIORATE PATHOLOGIES, AND SLOW DISEASE PROGRESSION. MOREOVER, ADA011 COULD BE USED ALONE OR IN COMBINATION WITH EMERGING GENE THERAPIES TO PREVENT PROGRESSION OF EXISTING FD IN PATIENTS. WE HAVE IDENTIFIED ADA011 AS A POTENT, WELL-TOLERATED TGF-SS1/3 INHIBITOR WITH EFFICACY INHIBITING ADIPOGENIC DIFFERENTIATION AN IN VITRO MODEL AND INHIBITING MUSCLE FD IN AN IN VIVO MOUSE MODEL OF INDUCED MUSCLE INJURY. WE PROPOSE TO USE ADA011 TO INHIBIT MUSCLE FD IN A MOUSE MODEL OF LGMD2B (DYSFERLIN-NULL). IN AIM 1 WE WILL TEST THIS HYPOTHESIS BY ANALYZING DISEASE PROGRESSION OVER 20 WEEKS IN DYSFERLIN-NULL MICE TREATED WITH ADA011 COMPARED TO VEHICLE CONTROL. IN AIM 2 WE WILL DETERMINE WHETHER MUSCLE HEALING AND FUNCTION ARE IMPROVED BY ADA011 TREATMENT AFTER ACUTE INJURY IN DYSFERLIN-NULL MICE. EFFICACY OF ADA011 IN THIS MOUSE MODEL OF LGMD2B WOULD POWERFULLY VALIDATE THE THERAPEUTIC POTENTIAL OF ADA011 AND SUPPORT DEVELOPMENT OF ADA011 AS A NOVEL THERAPY FOR LGMD2B PATIENTS. SINCE THERAPEUTICS THAT INHIBIT FD OF MUSCLES IN LGMB2B PATIENTS DO NOT EXIST, ADA011 WOULD BE A FIRST-IN-CLASS THERAPEUTIC THAT COULD SIGNIFICANTLY IMPROVE AND EXTEND HEALTH AND LIFESPAN OF LGMD2B PATIENTS.

LOMAS COMMUNITY PREVENTION COALITION - THE LOMAS COMMUNITY PREVENTION COALITION WAS AWARDED A FY2024 DRUG-FREE COMMUNITIES SUPPORT PROGRAM GRANT IN THE AMOUNT OF $125,000 BY THE WHITE HOUSE OFFICE OF NATIONAL DRUG CONTROL POLICY, IN COOPERATION WITH THE CENTER FOR DISEASE CONTROL AND PREVENTION. THE COALITION SERVES IN SAN GERMAN, PUERTO RICO, A COMMUNITY OF 31,879 POPULATION. THE GOALS OF THE COALITION ARE TO ESTABLISH AND STRENGTHEN COMMUNITY COLLABORATION IN SUPPORT OF LOCAL EFFORTS TO PREVENT YOUTH SUBSTANCE USE. THE COALITION WILL ACHIEVE ITS GOALS BY IMPLEMENTING THE SEVEN EVIDENCE-BASED STRATEGIES FOR PREVENTING DRUGS USE AND ABUSE. THE 12 COMMUNITY'S SECTORS COLLABORATIONS ARE NECESSARY TO IMPACT YOUNG PEOPLE AND WORK LIKE AN UNIFY GROUP TO ESTABLISH PROTECTIVE FACTORS FOR PREVENTION DRUGS USE.

VALUE- ADDED AGRICULTURAL PRODUCT MARKET DEVELOPMENT GRANTS

ASSISTANCE TO FIREFIGHTERS GRANTS

HPC WIPA PROJECT

PRODUCTION OF CELL LINES WITH IMPROVED REPROGRAMMING POTENTIAL FOR SCNT

EASTERN STATE PENITENTIARY HISTORIC SITE WILL REVISE AND EXPAND ITS RETURNING CITIZENS TOUR GUIDE PROJECT, WHICH IS DESIGNED TO FOSTER EMPATHY IN MUSEUM VISITORS, HUMANIZE MASS INCARCERATION, AND PROVIDE A GREATER UNDERSTANDING OF CONTEMPORARY CRIMINAL JUSTICE ISSUES. A NEW FULL-TIME MANAGERIAL POSITION WILL OVERSEE THE PROGRAM, WHICH WILL BE RENAMED LEAD: LIVED EXPERIENCE ACTIVATING DIALOGUE. THE MUSEUM WILL FILL THE POSITION WITH A FORMERLY INCARCERATED/RETURNING CITIZEN, WHOSE LIVED EXPERIENCE WILL ENHANCE RELATED TOURS AND PUBLIC PROGRAMS AND PROMOTE DIVERSITY, INCLUSION, AND ACCESS INITIATIVES ACROSS THE ENTIRE INSTITUTION. THE MUSEUM WILL ALSO ESTABLISH 12 LEAD FELLOWSHIPS FOR RETURNING CITIZENS WHO WILL SUPPORT COMMUNITY PARTNERSHIPS FOR PUBLIC PROGRAMMING AND PARTICIPATE IN TRAINING AND PROFESSIONAL DEVELOPMENT OPPORTUNITIES.

CENTERS FOR INDEPENDENT LIVING

HIGH SENSITIVITY TETHERED BICHROMOPHORIC VOLTAGE-SENSITIVE DYES

SBIR PHASE I: PROACTIVE NETWORK CONFIGURATION ANALYSIS

STTR PHASE I: HEMODYNAMIC EFFECTS INFORM DESIGN OF AN EXTERNAL STENT TO REDUCE DIALYSIS ACCESS FAILURES

ATTENTION HOMES' BASIC CENTER PROGRAM

TO COVER BICENTENNIAL ACTIVITIES, SUCH AS, BUT NOT LIMITED TO: PHOTO EXHIBITIONS, PD OUTREACH ACTIVITIES, CULTURAL PATRIMONY 3D MAPPING VIRTUAL TOURS, BICENTENNIAL CARTOON, PROMOTIONAL MATERIALS, AND U.S. EFFORTS UNDER THE BICENTENNIAL FRAMEWORK.

ALLIANCE FOR RESTORING RAINFOREST IN CA ON DEL USUMACINTA (PN6530)

HOMELESS ASSISTANCE

FY2023-2024 CENTERS FOR INDEPENDENT LIVING

FY 2025 ILCL ~ STATE PLAN INDEPENDENT LIVING CENTERS

FY2024-2025 CENTERS FOR INDEPENDENT LIVING

CONTINUUM OF CARE PROGRAM

HOMELESS ASSISTANCE

HOMELESS ASSISTANCE

HOMELESS ASSISTANCE

HOMELESS ASSISTANCE

SUPPORTIVE HOUSING PROGRAM

HOMELESS ASSISTANCE

THE ROAD TO SUSTAINABILITY IN BAJA CALIFORNIA, PRIORITIZING THREATS AND BUILDINGCAPACITY FOR EFFECTIVE MANAGEMENT, MONITORING, AND CONSERVATION OF THE CALIFORNIA CONDOR

FY2022-2023 CENTERS FOR INDEPENDENT LIVING

THE NASA INNOVATIVE ADVANCED CONCEPTS (NIAC) PROGRAM FOCUSES ON EARLY-STAGE FEASIBILITY STUDIES OF VISIONARY CONCEPTS THAT ADDRESS NATIONAL GOVERNMENT AND COMMERCIAL AEROSPACE GOALS. CONCEPTS ARE SOLICITED FROM ANY FIELD OF STUDY THAT OFFERS A RADICALLY DIFFERENT APPROACH OR DISRUPTIVE INNOVATION THAT MAY SIGNIFICANTLY ENHANCE OR ENABLE NEW HUMAN OR ROBOTIC SCIENCE AND EXPLORATION MISSIONS. THE NIAC PROGRAM SEEKS EXCITING UNEXPLORED CREDIBLE AEROSPACE CONCEPTS WITH AT LEAST ONE MISSION APPLICATION THAT ADDRESSES NASA GOALS OR OFFERS WIDER BENEFITS WITH SPACE OR AERONAUTICS APPLICATIONS. NIAC FOCUSES ON EARLY STUDIES OF VISIONARY AEROSPACE CONCEPTS. THESE AEROSPACE ARCHITECTURES PROPOSED IN THE CONTEXT OF A REPRESENTATIVE MISSION WILL GENERALLY ADVANCE FROM TECHNOLOGY READINESS LEVEL (TRL) 1-2 IN MATURITY AND ARE AIMED TEN OR MORE YEARS IN THE FUTURE.

2020 CILS

2019 CENTERS FOR INDEPENDENT LIVING

2021 CILS

EARMARK

2018 CENTERS FOR INDEPENDENT LIVING

2020 ILC3 - CARES

DEVELOPMENT OF DIGITAL AND INTERACTIVE METHODS TO TEACH IMMUNOLOGY

FIE EARMARK GRANT AWARDS

SSA WORK INCENTIVES PLANNING AND ASSISTANCE PROJECTS

RESEARCH ON VIOLENCE AND VICTIMIZATION ACROSS THE LIFE SPAN, SPECIAL TOPIC: OFFENDER INTERVENTIONS: WHY OFFENDERS DESIST FROM INTIMATE PARTNER VIOLEN

2017 CENTERS FOR INDEPENDENT LIVING

THIS PROJECT WILL DEVELOP AN INVENTORY OF THE CURRENT MUNICIPAL SOLID WASTE SITUATION OF SELECT MUNICIPALITIES IN FOUR STATES OF THE SOUTHEASTERN REG

SBIR PHASE I: PATENT FIGURE RECOGNITION

EMPOWERING SEVIER COUNTY'S ENTREPRENEURS (ESCE)

REVIVER PROJECT

STAFFING FOR ADEQUATE FIRE AND EMERGENCY RESPONSE (SAFER)

LOMAS COMMUNITY PREVENTION COALITION

FY22 PUBLIC HEALTH WORKFORCE FUNDING FOR PART C CILS

CONTINUUM OF CARE PROGRAM

RAPID: DECENTRALIZED TELEPHONIC TRIAGE SYSTEM FOR CHARITABLE CLINIC COVID-19 CRISIS RESPONSE

HOMELESS ASSISTANCE

HOMELESS ASSISTANCE

HOMELESS ASSISTANCE

HOMELESS ASSISTANCE

HOMELESS ASSISTANCE

SSA WORK INCENTIVES PLANNING AND ASSISTANCE PROJECTS

SSA WORK INCENTIVES PLANNING AND ASSISTANCE PROJECTS

SSA WORK INCENTIVES PLANNING AND ASSISTANCE PROJECTS

SUSTAINABLE FORESTRY MANAGEMENT IN THE SANGAY-PODOCARPUS CONSERVATION CORRI

HOMELESS ASSISTANCE

HOMELESS ASSISTANCE

A TIME FOR LIBERTY: OUR SHARED HISTORY, OUR SHARED FUTURE, PRESENTED BY EASTERN STATE PENITENTIARY HISTORIC SITE [AS THE UNITED STATES APPROACHES ITS 250TH ANNIVERSARY, EASTERN STATE PENITENTIARY HISTORIC SITE PROPOSES A ROBUST SUITE OF INTERPRETIVE PUBLIC PROGRAMMING TITLED?A TIME FOR LIBERTY: OUR SHARED HISTORY, OUR SHARED FUTURE. THIS INITIATIVE WILL ILLUMINATE THE PROFOUND INFLUENCE OF THE ENLIGHTENMENT AND THE FOUNDING ERA ON THE BIRTH OF AMERICAN DEMOCRACY AND THE CONCURRENT EVOLUTION OF THE AMERICAN JUSTICE SYSTEM. DRAWING DIRECTLY FROM THE PRINCIPLES ENSHRINED IN THE DECLARATION OF INDEPENDENCE AND THE U.S. CONSTITUTION, NATURAL RIGHTS, INDIVIDUAL LIBERTY, GOVERNMENT BY CONSENT, AND THE PURSUIT OF A MORE PERFECT UNION, THIS INITIATIVE WILL INVITE AUDIENCES OF ALL AGES INTO CONVERSATION AROUND OUR SHARED CIVIC INHERITANCE. THROUGHOUT THIS PROJECT, EASTERN STATE WILL HOST 14 PUBLIC PANEL DISCUSSIONS, LAUNCH 6 FAMILY-FRIENDLY COMMUNITY FESTIVALS, AND CREATE 3 "POP UP" EXHIBITS CONNECTING EASTERN STATE'S ARCHIVES TO THE SEMIQUINCENTENNIAL.]