Marian University

CARES HEERF INSTITUTION’S ALLOCATION OF HEER FUNDS

MARIAN UNIVERSITY WILL IMPLEMENT THE CITY CONNECTS MIDWEST: REIMAGINING STUDENT SUCCESS IN THE MAGIC CITY" WITH THE GARY COMMUNITY SCHOOL CORPORATION AND THE 21ST CENTURY CHARTER SCHOOLS."

ALLOCATIONS FOR SECTION 18004A1 OF CARES ACT

MARIAN UNIVERSITY EMERGENCY INSTITUTIONAL RELIEF FUND

MARIAN UNIVERSITY CARES ACT EMERGENCY FINANCIAL AID FOR STUDENTS

MARIAN UNIVERSITY WILL EXPAND THE PIPELINE OF HIGH-QUALITY, TRAINED PROVIDERS TO ADDRESS THE SHORTAGES OF MENTAL HEALTH SERVICE PROFESSIONALS IN INDIANAPOLIS PUBLIC SCHOOLS.

MARIAN UNIVERSITY WILL IMPLEMENT THE “CITY CONNECTS MIDWEST RURAL PILOT” FULL-SERVICE COMMUNITY SCHOOLS PROGRAM, WITH SHAKAMAK ELEMENTARY SCHOOL (SES) AND SHAKAMAK JUNIOR/SENIOR HIGH SCHOOL (SJSHS).

MARIAN PROMISE

MARIAN UNIVERSITY ELEVATE ENHANCING LEARNING, ENGAGEMENT, VALUE, ACCESS, TECHNOLOGY, AND EXCELLENCE

MARIAN UNIVERSITY UPWARD BOUND MATH SCIENCE PROGRAM

2017 MARIAN UNIVERSITY UPWARD BOUND MATH AND SCIENCE PROJECT - CONTINUATION

MARIAN UNIVERSITY - STUDENT SUPPORT SERVICES REGULAR CONTINUATION PROGRAM

STUDENT SUPPORT SERVICES PROGRAM

IMPROVING SECONDARY STEM TEACHER PREPARATION FOR HIGH-NEED SCHOOLS THROUGH DIVERSE TEACHING EXPERIENCES, INCLUDING SIMULATED VIRTUAL REALITY CLASSROOMS

RONALD E. MCNAIR POST-BACCALAUREATE ACHIEVEMENT

STUDENT SUPPORT SERVICES PROGRAM

ALLIED HEALTH AND STEM EDUCATION EQUIPMENT

UPWARD BOUND MATH & SCIENCE

HIGHER EDUCATION - INSTITUTIONAL AID - STRENGTHENING INSTITUTIONS

THE ROLES OF SPHINGOLIPIDS IN STRESS RESPONSE AND HEALTHY AGING.

CAREER: MITONUCLEAR CONFLICT AND CO-EVOLUTION IN A WILD POLYPLOID ANIMAL

STEM SCHOLARS: SUPPORTING GRADUATION OF BIOLOGY, CHEMISTRY, AND MATHEMATICS MAJORS BY DEVELOPING THEIR STEM ETHICAL KNOWLEDGE AND IDENTITY AS SCIENTISTS

MARIAN UNIVERSITY - STUDENT SUPPORT SERVICES REGULAR CONTINUATION PROJECT

MARIAN UNIVERSITY'S RESIDENT EDUCATOR AND ADMINISTRATOR PIPELINE (REAP) PROGRAM

HIGHER EDUCATION EMERGENCY RELIEF FUND-STRENGTHENING INSTITUTIONS PROGRAM

INVESTIGATING WHETHER CHLAMYDIA TRACHOMATIS CAN INCREASE THE INFECTIVITY OF HPV DURING GENITAL TRACT INFECTIONS - PROJECT SUMMARY ALTHOUGH THE ESTIMATED LIFETIME RISK OF HUMAN PAPILLOMAVIRUS (HPV) INFECTION CAN BE AS HIGH AS 75% IN UNVACCINATED WOMEN, THE ACTUAL RISK OF DEVELOPING CERVICAL CANCER IS ONLY ~0.68%. THIS INDICATES THAT EXPOSURE TO HPV ALONE IS INSUFFICIENT FOR THE DEVELOPMENT OF CERVICAL CANCER AND THAT HPV INFECTIONS LIKELY REQUIRE THE PRESENCE OF A BIOLOGICAL OR CELLULAR INDUCED “CO-FACTOR” TO HELP TRIGGER ONCOGENESIS. AS THE MOST COMMON BACTERIAL SEXUALLY TRANSMITTED PATHOGEN AND BECAUSE IT TOO IS A SIGNIFICANT THREAT TO THE REPRODUCTIVE HEALTH OF WOMEN, CHLAMYDIA TRACHOMATIS (CT) INFECTIONS ARE INCREASINGLY BEING LINKED TO GYNECOLOGICAL CANCER DEVELOPMENT AS EPIDEMIOLOGICAL REPORTS INDICATE THAT CO-INFECTIONS WITH CT AND HPV ARE RELATIVELY COMMON. META-ANALYSES OF THE EPIDEMIOLOGICAL DATA AND THE EARLY INVESTIGATIONS INTO THE PUTATIVE ROLE OF CT IN GYNECOLOGICAL CANCERS HAVE IMPLICATED THE CELLULAR IMMUNE RESPONSE TO CHLAMYDIAL INFECTION AS A POTENTIAL CO- FACTOR THAT CAN ENHANCE THE HOST’S SUSCEPTIBILITY TO HPV-INDUCED CERVICAL CANCERS. WE AND OTHERS HAVE SHOWN THAT THE IMMUNE RESPONSE TO CHLAMYDIA INFECTION RESULTS IN GENITAL TRACT PATHOLOGY AND OUR MOST RECENT REPORT SHOWS THAT TLR3 DEFICIENCY IN HUMAN OVIDUCT EPITHELIAL (HOE) CELLS ALTERS THE IMMUNE RESPONSE TO CT INFECTION, RESULTING IN INCREASED CHLAMYDIAL REPLICATION. WE ALSO RECENTLY REPORTED THAT CHLAMYDIA INFECTION INDUCES THE SYNTHESES OF CELLULAR FACTORS THAT DISRUPT CELL-CELL JUNCTIONS IN GENITAL TRACT TISSUE AND THAT TLR3 DEFICIENCY LEADS TO INCREASED MONOLAYER PERMEABILITY DURING CHLAMYDIA INFECTION. OUR DATA SUPPORT OTHER STUDIES SHOWING THAT CHLAMYDIA INFECTION CAN DISRUPT THE PROTECTIVE EPITHELIAL BARRIER FUNCTION, AND WE ALSO PRESENTED EVIDENCE THAT TLR3 PLAYS A ROLE IN MAINTAINING THE INTEGRITY OF THE EPITHELIAL BARRIER DURING GENITAL TRACT CHLAMYDIA INFECTION. THEREFORE, WE HYPOTHESIZE THAT CHLAMYDIA INFECTION DISRUPTS EPITHELIAL BARRIER FUNCTION (WHICH IS IN PART MODULATED BY TLR3), AND THE BARRIER DISRUPTION WILL ALLOW BETTER ACCESS TO THE UNDERLYING BASAL CELL LAYERS AND THEREBY CAN INCREASE THE INFECTIVITY OF HPV. IN THIS PROPOSAL, WE WILL TEST OUR HYPOTHESIS THAT CT CAN SERVE AS A CO-FACTOR IN HPV-INFECTION-INDUCED CERVICAL CANCER BY: (1) EXAMINING WHETHER CHLAMYDIA INFECTION OR SECRETED PRODUCTS OF CHLAMYDIA INFECTION CAN ENHANCE THE ATTACHMENT AND ENTRY OF HPV INTO THEIR TARGET CELLS, (2) DETERMINING IF TLR3 SIGNALING MODULATES THE IMPACT THAT CT HAS ON INCREASING HPV INFECTIVITY, AND (3) ASCERTAINING IF GENITAL TRACT CHLAMYDIA INFECTION WILL MAKE MICE MORE SUSCEPTIBLE TO SUBSEQUENT PAPILLOMAVIRUS INFECTIONS. CONFIRMATION OF OUR HYPOTHESIS WOULD REVEAL NOVEL INSIGHT INTO CT-HPV COINFECTION, THE ROLE OF TLR3 IN ALTERING OUTCOMES OF COINFECTION, AND IMPLICATE TLR3 AS A POTENTIAL TARGET FOR THERAPEUTIC INTERVENTIONS TO PREVENT CT-TRIGGERED ONCOGENESIS IN HPV-INFECTED PATIENTS.

ROLE OF THE SYMPATHETIC NERVOUS SYSTEM IN ROSACEA

MARIAN UNIVERSITY - HEERF STRENGTHENING INSTITUTIONS PROGRAM

MARIAN UNIVERSITY'S COMMUNITY OF CARE PROGRAM

PHYSIOLOGICAL RESPONSE OF ESCHERICHIA COLI TO TEMPERATURE AND DESICCATION STRESS

THIS PROJECT WILL SUPPORT AN INTENSIVE, SEVEN WEEK PROGRAM TARGETING SOCIOECONOMICALLY DIVERSE GROUP OF BOTH UNDERGRADUATE STUDENTS AND HIGH SCHOOL T

LYSINE METHYLATION AS A NOVEL REGULATORY MECHANISM OF HPV E2 FUNCTION - PROJECT ABSTRACT HUMAN PAPILLOMAVIRUSES (HPV) ARE DOUBLE-STRANDED DNA VIRUSES THAT INFECT CUTANEOUS AND MUCOSAL EPITHELIA. INFECTIONS WITH HIGH-RISK HPVS MAY LEAD TO CERVICAL, ANOGENITAL, AND OROPHARYNGEAL CANCERS ACCOUNTING FOR 5% OF ALL CANCERS WORLDWIDE. CURRENTLY THERE ARE NO EFFECTIVE NON-INVASIVE TREATMENTS AGAINST HIGH-RISK HPV INFECTIONS. BECAUSE OF THAT, IT IS CRITICAL TO STUDY THE FUNDAMENTAL BIOLOGY OF HIGH-RISK HPV AND SPECIFICALLY ITS UTILIZATION OF HOST CELL FACTORS TO PERMIT COMPLETION OF ITS VIRAL LIFE CYCLE. THE VIRAL REPLICATIVE PROGRAM CONSISTS OF THREE DIFFERENT STAGES: (1) INITIAL REPLICATION AFTER INFECTION, (2) STABLE MAINTENANCE OF VIRAL GENOMES AND (3) AMPLIFICATION OF VIRAL EPISOMES. THE PV ACTIVATOR E2 AND E1 DNA HELICASE PROTEINS ARE THE FIRST PROTEINS TO BE EXPRESSED AFTER INFECTION AND ARE ESSENTIAL FOR HPV REPLICATION. THE VIRAL E2 PROTEIN IS NECESSARY FOR REPLICATION OF THE VIRAL GENOME, ACTIVATION OF THE VIRAL EARLY PROMOTER FOR TRANSCRIPTION, AND TETHERING OF VIRAL GENOMES TO HOST MITOTIC CHROMOSOMES IN BASAL CELLS DURING CELLULAR REPLICATION AND DIVISION. OUR LONG-TERM GOAL IS TO ELUCIDATE HOST FACTORS NECESSARY FOR E1-E2 DEPENDENT HPV REPLICATION AND E2-MEDIATED TRANSCRIPTION THROUGHOUT THE VIRAL LIFECYCLE. PROTEIN LYSINE METHYLATION IS EMERGING AS AN IMPORTANT POST-TRANSLATIONAL MODIFICATION THAT REGULATES THE ACTIVITY OF TRANSCRIPTION FACTORS AND HISTONES. WE RECENTLY IDENTIFIED FOUR LYSINE RESIDUES METHYLATED WITHIN THE HPV-31 E2 BY MASS SPECTROMETRY CONFIRMING THAT E2 IS A METHYLATED PROTEIN. WE HYPOTHESIZE THAT THAT LYSINE METHYLATION IS AN IMPORTANT REGULATORY PROCESS DURING THE VIRAL LIFECYCLE. THE OVERALL OBJECTIVES IN THIS APPLICATION ARE TO (I) IDENTIFY THE LYSINE METHYL TRANSFERASES RESPONSIBLE FOR E2 METHYLATION AND (II) DETERMINE THEIR BIOLOGICAL FUNCTION. THE PROPOSED RESEARCH IS SIGNIFICANT BECAUSE IT WILL DEFINE THE MECHANISMS TIGHTLY CONTROLLED BY E2 METHYLATION THROUGHOUT THE HPV LIFECYCLE. ULTIMATELY, SUCH KNOWLEDGE HAS THE POTENTIAL TO TARGET MECHANISMS OF PERSISTENT HPV INFECTIONS.

EARMARKS

EARMARKS

MARIAN WASOMI WILL BE THE PILOT PROGRAM OF THE MARIAN GLOBAL SCHOLARS INITIATIVE, A FIVE-YEAR LANGUAGE ACQUISITION AND GLOBAL ENGAGEMENT PEDAGOGY INITIATIVE WITH IMMERSION PARTNERS IN SIX COUNTRIES.

ADVANCING WAKEFULNESS SCREENING OF SLEEP APNEA DISORDER THROUGH BREATHING SOUND ANALYSIS AND HARDWARE OPTIMIZATION - PROJECT SUMMARY/ABSTRACT SLEEP APNEA AFFECTS OVER ONE BILLION PEOPLE WORLDWIDE, WITH OBSTRUCTIVE SLEEP APNEA (OSA) ACCOUNTING FOR MORE THAN 85% OF CASES. OSA IS CHARACTERIZED BY REPEATED EPISODES OF AIRWAY OBSTRUCTION DURING SLEEP, LEADING TO FRAGMENTED SLEEP AND REDUCED OXYGEN LEVELS. OSA IS LINKED TO SEVERAL HEALTH COMPLICATIONS, INCLUDING CARDIOVASCULAR DISEASE, DIABETES, AND COGNITIVE IMPAIRMENT. DESPITE ITS PREVALENCE, OSA REMAINS SIGNIFICANTLY UNDERDIAGNOSED, ESPECIALLY IN UNDERSERVED POPULATIONS, DUE TO LIMITED ACCESS TO GOLD-STANDARD DIAGNOSTICS LIKE OVERNIGHT POLYSOMNOGRAPHY (PSG). EARLY DIAGNOSIS IS ESSENTIAL TO PREVENT LONG-TERM HEALTH ISSUES AND ALLEVIATE THE ASSOCIATED HEALTHCARE BURDEN. ADDITIONALLY, A QUICK AND OBJECTIVE OSA SCREENING COULD PREVENT UNNECESSARY SURGICAL PRECAUTIONS DUE TO THE LOW SPECIFICITY (~40%) OF WIDELY USED QUESTIONNAIRES, SUCH AS STOP-BANG. THIS PROJECT FOCUSES ON ENHANCING A WAKEFULNESS-BASED SLEEP APNEA SCREENING TOOL THAT UTILIZES BREATHING SOUND ANALYSIS TO ASSESS SLEEP APNEA RISK. THE TOOL OFFERS A NON-INVASIVE, OBJECTIVE, AND ACCESSIBLE SCREENING METHOD, ESPECIALLY FOR POPULATIONS WITH LIMITED ACCESS TO TRADITIONAL SLEEP STUDIES. HOWEVER, THE TOOL’S SCREENING ACCURACY, AFFORDABILITY, AND USABILITY MUST BE IMPROVED FOR LARGE-SCALE IMPLEMENTATION. WE PROPOSE THREE SPECIFIC AIMS TO ADDRESS THESE CHALLENGES. AIM 1 SEEKS TO REFINE THE TOOL’S ALGORITHM BY REDUCING THE INFLUENCE OF ANTHROPOMETRIC FACTORS ON SOUND FEATURE CLASSIFICATION AND INCORPORATING INTRA-SUBJECT VARIANCE TO ENHANCE RELIABILITY. DETERMINISTIC AND NON-DETERMINISTIC MACHINE LEARNING ALGORITHMS WILL BE INTEGRATED TO IMPROVE CLASSIFICATION OUTCOMES. AIM 2 WILL APPLY MACHINE LEARNING, ADVANCED SIGNAL PROCESSING, AND STATISTICAL ANALYSIS TECHNIQUES TO IDENTIFY ACOUSTIC FEATURES THAT CORRELATE WITH AND PREDICT THE APNEA-HYPOPNEA INDEX (AHI) AND OTHER SLEEP METRICS, SUCH AS OXYGEN DESATURATION INDEX AND APNEA INDEX. AIM 3 FOCUSES ON THE DEVELOPMENT OF CUSTOM HARDWARE AND A MICROPHONE CHAMBER FOR IMPROVED BREATHING SOUND RECORDING AND PROCESSING, AIMING TO CREATE A MORE PORTABLE, COST-EFFECTIVE, AND USER-FRIENDLY DEVICE FOR BROAD ADOPTION. OUR LONG-TERM GOAL IS TO PROVIDE AN ACCESSIBLE, WAKEFULNESS-BASED SCREENING TOOL FOR EARLY DETECTION OF SLEEP APNEA AND ASSESSMENT OF SLEEP QUALITY METRICS, PARTICULARLY IN UNDERSERVED POPULATIONS AND INDIVIDUALS UNDERGOING SURGERIES REQUIRING FULL ANESTHESIA. THIS TOOL HAS THE POTENTIAL TO REDUCE DIAGNOSTIC TIME AND COSTS, IMPROVE EARLY INTERVENTION RATES, AND DECREASE THE RISK OF UNTREATED SLEEP APNEA LEADING TO SEVERE HEALTH COMPLICATIONS. THE PROPOSED R03 PROJECT WILL GENERATE KEY INSIGHTS AND MODELS FOR FUTURE CLINICAL TRIALS AND BROADER IMPLEMENTATION. BY IMPROVING THE ACCURACY AND USABILITY OF THIS SCREENING TOOL, THE RESEARCH AIMS TO ADDRESS CRITICAL PUBLIC HEALTH NEEDS, ESPECIALLY IN RURAL OR LOW-RESOURCE SETTINGS WHERE ACCESS TO CONVENTIONAL SLEEP DIAGNOSTICS IS LIMITED. IF SUCCESSFUL, THE TOOL COULD SIGNIFICANTLY IMPACT SLEEP APNEA DIAGNOSIS AND TREATMENT, LEADING TO BETTER PATIENT OUTCOMES AND A REDUCTION IN HEALTHCARE COSTS ASSOCIATED WITH UNTREATED SLEEP APNEA.

NMUR2 IN BONE FORMATION - PROJECT SUMMARY THE LONG-TERM GOAL OF THIS PROJECT IS TO ESTABLISH THE MOLECULAR PATHWAY USED BY NEUROMEDIN-U (NMU) IN THE NEGATIVE REGULATION OF BONE FORMATION. THIS IS SIGNIFICANT SINCE STUDIES IN MICE INDICATE NMU NEGATIVELY REGULATES BONE FORMATION IN VIVO, MAKING THE NMU PATHWAY A POTENTIAL THERAPEUTIC TARGET FOR TREATING OSTEOPOROSIS, A DISEASE THAT PLACES INDIVIDUALS AT ENHANCED RISK FOR FRACTURE, DISABILITY, AND DEATH. HOSPITALIZATIONS FOR OSTEOPOROTIC FRACTURE EXCEEDS THOSE FOR HEART ATTACK, STROKE, AND BREAST CANCER, AND DIRECT MEDICAL COSTS FOR OSTEOPOROSIS IN THE US ARE ESTIMATED TO BE APPROXIMATELY $20 BILLION. DESPITE THIS, THERE ARE LIMITED TREATMENT OPTIONS FOR OSTEOPOROSIS, PARTICULARLY FOR LONG-TERM MANAGEMENT OF THIS CHRONIC CONDITION, AND THE AVAILABLE PHARMACOLOGICAL THERAPIES HAVE SIGNIFICANT DRAWBACKS. CONSEQUENTLY, THERE IS AN URGENT NEED FOR DEVELOPING NEW THERAPEUTIC APPROACHES FOR TREATING OSTEOPOROSIS. THE PROPOSED R03 WILL FOLLOW A NOVEL LINE OF INVESTIGATION TO EXAMINE THE ROLE OF THE NMU PATHWAY IN THE RESTRICTION OF BONE FORMATION. WORK BY THIS RESEARCH TEAM AND OTHERS DEMONSTRATES THAT ENDOGENOUS NMU SUPPRESSES OSTEOBLAST DIFFERENTIATION AND FUNCTION; HOWEVER, A POOR UNDERSTANDING OF THE MOLECULAR PATHWAY UTILIZED BY NMU TO SUPPRESS BONE FORMATION RESTRICTS TRANSLATIONAL OPPORTUNITIES AT PRESENT. THIS R03 PROPOSAL SEEKS TO ADDRESS THIS LIMITATION BY DETERMINING THE FUNCTIONAL ROLE OF NMU RECEPTOR 2 (NMUR2) IN THE SKELETON IN VIVO AND TO TEST THE HYPOTHESIS THAT NMUR2 IS REQUIRED FOR NMU- MEDIATED SUPPRESSION OF BONE FORMATION. USING A NOVEL MOUSE LINE IN WHICH NMUR2 EXPRESSION IS LOST IN THE APPENDICULAR SKELETON, WE WILL EXAMINE THE ROLE OF NMUR2 THROUGH QUANTIFICATION OF BONE MASS, QUANTITATIVE HISTOLOGICAL ANALYSES, SERUM MARKERS OF BONE TURNOVER, AND HIGH-THROUGHPUT SIGNALING ARRAYS FOR EXAMINING HUNDREDS OF POTENTIAL EFFECTORS DOWNSTREAM OF NMUR2 IN BONE. THIS PROJECT IS AN EXCELLENT FIT FOR THE GOALS OF THE R03 FUNDING MECHANISM IN THAT 1) IT PROVIDES A FOUNDATION FOR FUTURE PROJECTS IN A NOVEL LINE OF INVESTIGATION; 2) IT CAN BE CARRIED OUT IN A SHORT PERIOD OF TIME WITH LIMITED RESOURCES; 3) IS RELATIVELY SMALL IN COST, SCALE, AND DURATION; 4) AND IS SELF-CONTAINED. MOREOVER, UPON COMPLETION, THESE FINDINGS WILL PROVIDE ESSENTIAL PRELIMINARY DATA FOR FUTURE, LARGER SCALE STUDIES AIMED AT COMPLETE CHARACTERIZATION OF THE NMU SIGNALING PATHWAY IN THE SKELETON, WHICH MAY IDENTIFY NOVEL STRATEGIES FOR INHIBITING ITS EFFECTS THROUGH PHARMACOLOGICAL MEANS SUCH AS SMALL MOLECULES OR NEUTRALIZING ANTIBODIES.

THIS CURRENT PROJECT IS PART OF A THREE-YEAR EFFORT TO ADVANCE THE RECOVERY OF THE CHIRICAHUA LEOPARD FROG BY USING GENOMIC MARKERS TO QUANTIFY THE GENETIC DIVERSITY OF EXISTING CAPTIVE, REINTRODUCED, AND WILD POPULATIONS. THE CHIRICAHUA LEOPARD FROG IS LISTED AS A THREATENED SPECIES UNDER THE U.S. ENDANGERED SPECIES ACT. EVERY SPECIES LISTED UNDER THE ENDANGERED SPECIES ACT HAS A RECOVERY PLAN THAT SERVES AS A ROAD MAP FOR ACTIONS THAT WILL LEAD TO THE SPECIES NO LONGER NEEDING THE PROTECTIONS AFFORDED BY THE ENDANGERED SPECIES ACT. THIS PROJECT WILL PRIMARILY ADDRESS THREE PRIORITY 1 RECOVERY ACTIONS FOR THE CHIRICAHUA LEOPARD FROG THAT ARE OUTLINED IN ITS RECOVERY PLAN: IDENTIFY THE GENETIC RELATIONSHIPS OF POPULATIONS, ESTABLISH REFUGIA POPULATIONS, AND ESTABLISH NEW OR RE-ESTABLISH FORMER POPULATIONS. THE NEW INFORMATION WILL FORM THE BASIS FOR DEVELOPING A GENETIC MANAGEMENT PLAN TO GUIDE RECOVERY IMPLEMENTATION OF THE SPECIES BY A LONGSTANDING PARTNERSHIP. THE CHIRICAHUA LEOPARD FROG PARTNERSHIP IS A HIGHLY EFFECTIVE COLLABORATION THAT WORKS ACROSS STATE, FEDERAL, AND PRIVATE JURISDICTIONS TO ACHIEVE RANGE-WIDE CONSERVATION ACTIONS FOR THE CHIRICAHUA LEOPARD FROG. YEAR ONE OF THE OVERALL PROJECTFOCUSED ON SAMPLE AND SITE DATA COLLECTION, PRELIMINARY SEQUENCING TO DETERMINE APPROPRIATE SEQUENCING DEPTH AND BALANCE BETWEEN SEQUENCE DEPTH AND NUMBER OF SAMPLES, AND PREPARING BIOINFORMATICS STUDY DESIGN. DURING YEAR TWO, MARIAN UNIVERSITY COMPLETE REMAINING SEQUENCING OF THE SAMPLES COLLECTED FROM FROGS, ANALYZE OF THE MILLIONS OF DNA STRANDS PRODUCED ACROSS MANY HUNDREDS OF SAMPLES, AND BEGIN PREPARING A REPORT. WE HAVE ALSO BUDGETED FOR MEETINGS WITH THE CHIRICAHUA LEOPARD FROG PARTNERSHIP TO DISCUSS THE PROGRESS OF THE WORK AND PROVIDE CONTEXT FOR HOW THESE ACTIVITIES FIT WITH OTHER ONGOING AND FUTURE MANAGEMENT EFFORTS FOR THE SPECIES. THE CURRENT FUNDED ACTIVITIES FOR YEAR TWO WILL OCCUR DURING CALENDAR YEAR 2022.

SCHOLARSHIPS FOR DISADVANTAGED STUDENTS

ADVANCED EDUCATION NURSING TRAINEESHIP

DEVELOPING A MOUSE MODEL TO EXAMINE THE SPECIFIC IMPACT OF IFNA IN THE PATHOGENESIS OF GENITAL TRACT CHLAMYDIA INFECTION

2026-2027 TEACH BASE RECORD

NSL - BACCALAUREATE NURSING - CORRECTIONS IN BUDGET PERIOD/PROJECT PERIOD