University Of Georgia Research Foundation Inc

SAVANNAH RIVER ECOLOGY LABORATORY.

SAVANNAH RIVER ECOLOGY LABORATORY

PEANUT RESEARCH INNOVATION LAB (PRIL)

** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** COORDINATE THE USDA SARE (SUSTAINABLE AGRICULTURE RESEARCH AND EDUCATION) PROGRAM FOR THE 13 STATES AND 2 TERRITORIES OF THE SOUTHERN REGION. EACH AGREEMENT SUPPORTS APPROXIMATELY 13 RESEARCH AND EDUCATION PROJECTS, 13 EDUCATION PROJECTS, APPROXIMATELY 20 GRADUATE STUDENT PROJECTS, APPROXIMATELY 10 ON-FARM RESEARCH PROJECTS, APPROXIMATELY 9 FARMER PROJECTS, APPROXIMATELY 8 PROFESSIONAL DEVELOPMENT PROGRAM COMPETITIVEPROJECTS,APPROXIMATELY 20 PDP MODEL STATE PROGRAM TRAINING GRANTS AND 14 MODEL STATE PROGRAM-PROGRAM ASSISTANT GRANTS. REGIONAL COMPETITIVE GRANTS PROGRAM TO HELP AGRICULTURE BECOME MORE PROFITABLE, PROTECT NATURAL RESOURCES AND THE ENVIRONMENT AND IMPROVE QUALITY OF LIFE FOR RURAL COMMUNITIES.

REDUCING TRAFFICKING AMONG CHILDREN IN SUB SAHARAN AFRICA

UNDERSTANDING MECHANISMS OF HESC SELF-RENEWAL AND CELL FATE COMMITMENT

BIOPOPLAR: A TUNABLE CHASSIS FOR DIVERSIFIED BIOPRODUCT PRODUCTION

SREL

RESOURCE FOR INTEGRATED GLYCOTECHNOLOGY

NATIONAL CENTER FOR BIOMEDICAL GLYCOMICS

BIOFOUNDRY: GLYCOSCIENCE RESOURCES, EDUCATION, AND TRAINING (BIOF:GREAT) -THE BIOFOUNDRY: GLYCOSCIENCE RESOURCES, EDUCATION, AND TRAINING (BIOF:GREAT) WILL DEVELOP NEW RESEARCH, TECHNOLOGIES, AND INSTRUCTIONAL EXPERIENCES TO ALLOW A BROADER ADOPTION OF GLYCOSCIENCE INTO RESEARCH ENVIRONMENTS AND EDUCATION CURRICULUMS. ALTHOUGH GLYCANS, ALSO REFERRED TO AS COMPLEX CARBOHYDRATES, ARE ONE OF THE FOUR CLASSES OF BIOMOLECULES FOUND IN ALL LIVING ORGANISMS, THEY HAVE BEEN CONSISTENTLY UNDERSTUDIED IN THE LABORATORY AND UNDERTAUGHT IN THE CLASSROOM. THIS IS DESPITE THE FACT THAT BIOFUEL AND BIOMATERIAL EFFORTS RELY HEAVILY ON GLYCAN BIOMASS FROM PLANTS, THE VAST MAJORITY OF BIOLOGICS IN MEDICINE ARE GLYCOPROTEINS, AND GLYCANS ARE FOUND ON CELL SURFACES OF ALL LIVING CELLS WHERE THEY CONTRIBUTE TO CELL INTERACTIONS AND DIVERSE BIOLOGICAL FUNCTIONS. UNLIKE DNA/RNA AND PROTEINS, GLYCANS ARE RARELY LINEAR POLYMERS AND ARE NOT GENERATED BY TEMPLATE-BASED PROCESSES. THIS COMPLEXITY HAS MADE THEM DIFFICULT TO STUDY AT THE BENCH AND CHALLENGING TO TEACH IN THE CLASSROOM. BIOF:GREAT WILL LEVERAGE A BROAD RANGE OF EXPERTISE, INCLUDING AI AND MACHINE LEARNING, TO GENERATE RESEARCH TOOLS AND TECHNOLOGIES, WHILE ALSO DEVELOPING AND DEPLOYING NOVEL INSTRUCTIONAL AND TRAINING STRATEGIES, RESOURCES, RESEARCH MATERIALS, AND AUTOMATED TOOLS IN THE FIELD TO PROPEL GLYCOSCIENCE INTO THE SCIENTIFIC MAINSTREAM AND LEAD TO PARADIGM SHIFTS IN GLYCOSCIENCE EDUCATION. BIOF:GREAT DISCOVERIES AND DELIVERABLES ARE EXPECTED TO LEAD TO COMMERCIAL APPLICATIONS IN BIOENERGY, BIOENGINEERING, BIOMATERIALS, AND BIOMEDICINE. THE BIOFOUNDRY: GLYCOSCIENCE RESOURCES, EDUCATION, AND TRAINING (BIOF:GREAT) WILL TAKE ADVANTAGE OF THE COMPLEX CARBOHYDRATE RESEARCH CENTER (CCRC) AT THE UNIVERSITY OF GEORGIA (UGA), HOME TO ONE OF THE LARGEST COMMUNITIES OF GLYCOBIOLOGISTS IN THE WORLD, COUPLED WITH UGA EXPERTS IN BIOINFORMATICS/MACHINE LEARNING AND PEDAGOGY/EVALUATION. THE RESEARCH TEAM WILL FOCUS ON THREE SYNERGISTIC GOALS: 1) BIOINFORMATIC TOOLS/MACHINE LEARNING/ARTIFICIAL INTELLIGENCE (AI) TO PREDICT AND DEFINE GLYCOENZYMES AND GLYCOPROTEINS, 2) GLYCOENZYME EXPRESSION, CHARACTERIZATION, AND MANIPULATION, AND 3) MASS SPECTROMETRY-FACILITATED ANALYSES OF GLYCAN MODIFICATIONS. THE TECHNOLOGY DEVELOPMENT TEAM WILL FOCUS ON FOUR THEMES THAT WILL GENERATE 1) EXPRESSION LIBRARIES FOR GLYCOENZYMES FROM DIVERSE SPECIES SOURCES, 2) FINE-TUNED PROTEIN LANGUAGE MODELS AND NEW USER-FRIENDLY INFORMATICS TOOLS FOR CLASSIFYING AND PREDICTING GLYCOENZYMES AND SITE-SPECIFIC GLYCOSYLATION OF GLYCOPROTEINS, 3) ENGINEERED GLYCOENZYMES FOR GENERATING NOVEL CHEMICAL BIOLOGY TOOLS, AND 4) SPECIES-AGNOSTIC METHODS FOR THE MASS SPECTROMETRY-BASED ANALYSES OF GLYCOPROTEINS. THE USER FACILITY WILL PROVIDE HANDS-ON TRAINING AND SERVICE USING CUTTING-EDGE COMPUTATIONAL, ENZYMATIC, AND ANALYTICAL GLYCOSCIENCE APPROACHES. COLLABORATION AMONG USER FACILITY, RESEARCH, AND TECHNOLOGY DEVELOPMENT TEAMS WILL LEAD TO THE DEPLOYMENT OF NEW TECHNOLOGIES TO CATALYZE IN-HOUSE RESEARCH AND TECHNOLOGY DEVELOPMENT EFFORTS. THE USER FACILITY WILL EQUALLY FOCUS ON EXTERNAL GLYCOBIOLOGY RESEARCH PROJECTS SPANNING THE TREE OF LIFE IN PARTNERSHIPS WITH SCIENTISTS AT R1 AND NON-R1 SCHOOLS INCLUDING MINORITY-, PRIMARILY UNDERGRADUATE-, AND EPSCOR-SERVING INSTITUTIONS. THE EDUCATION/INSTRUCTION TEAM WILL ESTABLISH AND EVALUATE A SUITE OF INSTRUCTIONAL EXPERIENCES, INCLUDING SMALL MODULES FOR EXISTING CHEMISTRY/BIOLOGY COURSES, DEDICATED STAND-ALONE GLYCOSCIENCE COURSES AT THE UNDERGRADUATE/GRADUATE LEVEL, AND HANDS-ON SUMMER COURSES FOR BEGINNERS AND EXPERTS WITH RIGOROUS ATTENTION TO BEST PEDAGOGICAL PRACTICES AND EVALUATION FOR IMPROVEMENT. OUR PLATFORM-SHARING TEAM WILL FACILITATE THE TRANSFER OF DELIVERABLES FROM THE BENCH AND THE CLASSROOM TO ACADEMIC, GOVERNMENT, AND COMMERCIAL/INDUSTRIAL RESEARCH COMMUNITIES USING A KNOWLEDGE GRAPH FRAMEWORK CONSISTENT WITH THE PROTOTYPE OPEN KNOWLEDGE NETWORK (PROTO-OKN). BY PROVIDING EQUITABLE ACCESS TO ADVANCED INFRASTRUCTURE AND RESOURCES IN GLYCOSCIENCE, BIOF:GREAT WILL ADVANCE SCIENTIFIC INQUIRY AND EDUCATION IN BIOSCIENCES ACROSS ALL KINGDOMS OF LIFE. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

SYSTEMS ANALYSIS OF THE BENEFICIAL ASSOCIATIONS OF SORGHUM WITH ARBUSCULAR MYCRORRHIZAL FUNGI STUDIED WITH GENETICS, GENOMICS, IMAGING AND MICROBIOMICS

COORDINATE THE USDA SARE (SUSTAINABLE AGRICULTURE RESEARCH AND EDUCATION) PROGRAM FOR THE 13 STATES AND 2 TERRITORIES OF THE SOUTHERN REGION. EACH AGREEMENT SUPPORTS APPROXIMATELY 13 RESEARCH AND EDUCATION PROJECTS, 13 EDUCATION PROJECTS, APPROXIMATELY 20 GRADUATE STUDENT PROJECTS, APPROXIMATELY 10 ON-FARM RESEARCH PROJECTS, APPROXIMATELY 13 FARMER PROJECTS, APPROXIMATELY 8 PROFESSIONAL DEVELOPMENT PROGRAM COMPETITIVEPROJECTS,APPROXIMATELY 29 PDP MODEL STATE PROGRAM TRAINING GRANTS AND 29 MODEL STATE PROGRAM-PROGRAM ASSISTANT GRANTS. REGIONAL COMPETITIVE GRANTS PROGRAM TO HELP AGRICULTURE BECOME MORE PROFITABLE, PROTECT NATURAL RESOURCES AND THE ENVIRONMENT AND IMPROVE COMMUNITY QUALITY OF LIFE.

** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** COORDINATE THE USDA SARE (SUSTAINABLE AGRICULTURE RESEARCH AND EDUCATION) PROGRAM FOR THE 13 STATES AND 2 TERRITORIES OF THE SOUTHERN REGION. EACH AGREEMENT SUPPORTS APPROXIMATELY 13 RESEARCH AND EDUCATION PROJECTS, 13 EDUCATION PROJECTS, APPROXIMATELY 20 GRADUATE STUDENT PROJECTS, APPROXIMATELY 10 ON-FARM RESEARCH PROJECTS, APPROXIMATELY 13 FARMER PROJECTS, APPROXIMATELY 8 PROFESSIONAL DEVELOPMENT PROGRAM COMPETITIVEPROJECTS,APPROXIMATELY 29 PDP MODEL STATE PROGRAM TRAINING GRANTS AND 29 MODEL STATE PROGRAM-PROGRAM ASSISTANT GRANTS. REGIONAL COMPETITIVE GRANTS PROGRAM TO HELP AGRICULTURE BECOME MORE PROFITABLE, PROTECT NATURAL RESOURCES AND THE ENVIRONMENT AND IMPROVE QUALITY OF LIFE FOR RURAL COMMUNITIES.

COORDINATE THE USDA SARE (SUSTAINABLE AGRICULTURE RESEARCH AND EDUCATION) PROGRAM FOR THE 13 STATES AND 2 TERRITORIES OF THE SOUTHERN REGION. EACH AGREEMENT SUPPORTS APPROXIMATELY 13 RESEARCH AND EDUCATION PROJECTS 13 EDUCATION PROJECTS APPROXIMATELY 20 GRADUATE STUDENT PROJECTS APPROXIMATELY 10 ON-FARM RESEARCH PROJECTS APPROXIMATELY 13 FARMER PROJECTS APPROXIMATELY 8 PROFESSIONAL DEVELOPMENT PROGRAM COMPETITIVEPROJECTSAPPROXIMATELY 29 PDP MODEL STATE PROGRAM TRAINING GRANTS AND 29 MODEL STATE PROGRAM-PROGRAM ASSISTANT GRANTS. REGIONAL COMPETITIVE GRANTS PROGRAM TO HELP AGRICULTURE BECOME MORE PROFITABLE PROTECT NATURAL RESOURCES AND IMPROVE QUALITY OF LIFE FOR FARMERS RANCHERS FARM EMPLOYEES AND OUR COMMUNITIES.

GENAI EMPOWERED NATIONAL INITIATIVE FOR UPHOLDING STEM+C EDUCATION (GENIUS)

THE CENTER FOR PLANT AND MICROBIAL COMPLEX CARBOHYDRATES AT THE UNIVERSITY OF GEORGIA COMPLEX CARBOHYDRATE RESEARCH CENTER

** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** COORDINATE THE USDA SARE (SUSTAINABLE AGRICULTURE RESEARCH AND EDUCATION) PROGRAM FOR THE 13 STATES AND 2 TERRITORIES OF THE SOUTHERN REGION. EACH AGREEMENT SUPPORTS APPROXIMATELY 15 RESEARCH AND EDUCATION PROJECTS, 6 EDUCATION PROJECTS, APPROXIMATELY 15 GRADUATE STUDENT PROJECTS, APPROXIMATELY 10 ON-FARM RESEARCH PROJECTS, APPROXIMATELY 9 FARMER PROJECTS, APPROXIMATELY 8 PROFESSIONAL DEVELOPMENT PROGRAM COMPETITIVEPROJECTS, AND APPROXIMATELY 20 PDP STATE PLANS/MODEL STATE PROGRAMS. REGIONAL COMPETITIVE GRANTS PROGRAM TO HELP AGRICULTURE BECOME MORE PROFITABLE, PROTECT NATURAL RESOURCES AND THE ENVIRONMENT AND IMPROVE QUALITY OF LIFE FOR RURAL COMMUNITIES.

A TRANSDICIPLINARY CENTER FOCUSED ON RURAL AFRICAN AMERICAN FAMILIES

COMPUTATIONAL AND INFORMATICS RESOURCES AND TOOLS FOR GLYCOSCIENCE RESEARCH

NEUROSCIENCE, IMMUNOLOGY, SOCIAL ADVERSITY AND THE ROOTS OF ADDICTIVE BEHAVIORS: TOWARD A NEW FRAMEWORK FOR DRUG USE ETIOLOGY AND PREVENTION

UGARF SHALL PERFORM THE FOLLOWING 12 PROJECTS (SEE SEQUENTIALLY NUMBERED ATTACHMENTS 1-12) IN ACCORDANCE WITH THEIR SUBMITTED PROPOSAL SCOPES, MILEST

CONTEXTUAL PROCESSES AND RURAL AFRICAN AMERICAN EMERGING ADULTS

RESEARCH RESOURCE FOR INTEGRATED GLYCOTECHNOLOGY

** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** COORDINATE THE USDA SARE (SUSTAINABLE AGRICULTURE RESEARCH AND EDUCATION) PROGRAM FOR THE 13 STATES AND 2 TERRITORIES OF THE SOUTHERN REGION. EACH AGREEMENT SUPPORTS APPROXIMATELY 15 RESEARCH AND EDUCATION PROJECTS, APPROXIMATELY 10 GRADUATE STUDENT PROJECTS, APPROXIMATELY 10 ON-FARM RESEARCH PROJECTS, APPROXIMATELY 7 FARMER PROJECTS, APPROXIMATELY 7 PROFESSIONAL DEVELOPMENT PROGRAM COMPETITIVEPROJECTS, AND APPROXIMATELY 20 PDP STATE PLANS/MODEL STATE PROGRAMS. REGIONAL COMPETITIVE GRANTS PROGRAM TO HELP AGRICULTURE BECOME MORE PROFITABLE, PROTECT NATURAL RESOURCES AND THE ENVIRONMENT AND IMPROVE QUALITY OF LIFE FOR RURAL COMMUNITIES.

**AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** COORDINATE THE USDA SARE (SUSTAINABLE AGRICULTURE RESEARCH AND EDUCATION) PROGRAM FOR THE 13 STATES AND 2 TERRITORIES OF THE SOUTHERN REGION. EACH AGREEMENT SUPPORTS APPROXIMATELY 15 RESEARCH AND EDUCATION PROJECTS, APPROXIMATELY 10 GRADUATE STUDENT PROJECTS, APPROXIMATELY 10 ON-FARM RESEARCH PROJECTS, APPROXIMATELY 7 FARMER PROJECTS, APPROXIMATELY 7 PROFESSIONAL DEVELOPMENT PROGRAM COMPETITIVEPROJECTS, AND APPROXIMATELY 20 PDP STATE PLANS/MODEL STATE PROGRAMS. REGIONAL COMPETITIVE GRANTS PROGRAM TO HELP AGRICULTURE BECOME MORE PROFITABLE, PROTECT NATURAL RESOURCES AND THE ENVIRONMENT AND IMPROVE QUALITY OF LIFE FOR RURAL COMMUNITIES.

THE UNIVERSITY OF GEORGIA WILL BE AWARDED $8,040,831 TO RESTORE SALT MARSH ON JULIAS ISLAND, FLORIDA, BIRD-LONG ISLAND, GEORGIA, CAPE ROMAIN, SOUTH CAROLINA, AND CAPE LOOKOUT NATIONAL SEASHORE, NORTH CAROLINA THAT INCLUDE REGIONALLY SIGNIFICANT FISH AND WILDLIFE HABITAT WITHIN THE ONE MILLION ACRE STRETCH OF THE SOUTH ATLANTIC SALT MARSH FROM NORTH CAROLINA TO EAST-CENTRAL FLORIDA. THIS WORK WILL SUPPORT THE PRODUCTION OF FOOD, NURSERY HABITAT, AND REFUGE FOR MORE THAN 75% OF FISHERIES SPECIES, INCLUDING SHRIMP, OYSTERS, AND POPULAR FINFISH SUCH AS REDFISH AND FLOUNDER. THIS WORK IS BEING FUNDED BY THE COMMUNITY-BASED RESTORATION PROGRAM.

SOUTHERN APPALACHIA ON THE EDGE - EXURBANIZATION & CLIMATE INTERACTION IN THE SOUTHEAST

UGA/SKIO R/V SAVANNAH SHIP OPERATIONS - CY 2018-2022

MAMMALIAN GLYCOSYLTRANSFERASES FOR USE IN CHEMISTRY AND BIOLOGY

TO REDUCE THE PREVALENCE OF HUMAN TRAFFICKING THROUGH INCREASING THE FINANCIAL LITERACY AND CAPABILITY OF SURVIVORS AND THOSE AT-RISK IN SSA

NOVEL REENGINEERED MICROBIOME-BASED BIOLOGIC THERAPY TO TREAT COGNITIVE AND BEHAVIORAL SYMPTOMS OF ALZHEIMER'S DISEASE AND RELATED DEMENTIAS - ABSTRACT OUR EARLY-STAGE ADDP PROPOSAL AIMS TO DEVELOP A NOVEL GENETICALLY ENGINEERED BACTERIAL BIOLOGIC TO TREAT THE MOST COMMON EARLY SYMPTOMS OF ALZHEIMER'S DISEASE (AD), INCLUDING COGNITIVE IMPAIRMENT AND OTHER NEUROPSYCHOLOGICAL SYMPTOMS, SUCH AS ANXIETY AND DEPRESSION. THIS DEBILITATING DISEASE IMPOSES A HUGE EMOTIONAL, SOCIAL AND FINANCIAL BURDEN ON SOCIETY. NO EFFECTIVE DISEASE-MODIFYING AD DRUG EXISTS TO DAMPEN THE ASS AND TAU PROTEINOPATHIES ASSOCIATED WITH DISEASE PROGRESSION. CURRENT FDA-APPROVED CHOLINERGIC AND GLUTAMATERGIC NEUROTHERAPEUTICS ARE VERY MODEST AT BEST IN RESCUING MEMORY IN MILD COGNITIVE IMPAIRMENT (MCI) AND PRODROMAL OR EARLY STAGES OF AD CASES, AND OFTEN WORSEN ANXIETY, APATHY, DEPRESSION, AGITATION, AND OTHER NEUROBEHAVIORAL SYMPTOMS, GI IRRITATIONS, AND EVEN MORTALITY. RECENT BIOLOGICAL EVIDENCE INDICATES THAT AD IS A NEURAL CIRCUIT DISORDER. THE ONSET AND PROGRESSION OF COGNITIVE AND BEHAVIORAL SYMPTOMS INVOLVE A DEFICIENCY IN MONOAMINE NEUROTRANSMITTER SIGNALING NETWORKS, INCLUDING NOREPINEPHRINE (NE) AND DOPAMINE (DA). THUS, WE PROPOSE THAT RESTORING BRAIN DA/NE INPUTS HOLDS THE EXCELLENT POTENTIAL TO BE AN EFFECTIVE APPROACH TO ALLEVIATING COGNITIVE AND BEHAVIORAL DEFICITS IN AD AND COULD EVEN DELAY DISEASE ONSET. CURRENTLY, ORAL TABLET DOSING OF L- DOPA/CARBIDOPA 3-4 TIMES/DAY REMAINS THE MOST EFFECTIVE THERAPY AT RESTORING BRAIN DA/NE LEVELS IN HUMANS. HOWEVER, THIS REPEATED CHRONIC PULSATILE DELIVERY CAUSES SEVERE SIDE EFFECTS. THUS, OUR THERAPEUTIC HYPOTHESIS TO ADDRESS THIS UNMET CLINICAL PROBLEM IS THAT SYSTEMIC DELIVERY OF GENETICALLY ENGINEERED L-DOPA BACTERIAL LIVE- THERAPEUTICS (LDBL) WILL AVOID LARGE FLUCTUATIONS IN PLASMA L-DOPA AND PROVIDE MORE CONSISTENT DELIVERY OF L- DOPA TO THE BRAIN FOR RESTORING DA/NE TO STABLE LEVELS THAT BETTER RELIEVE AD SYMPTOMS WITHOUT ADDITIONAL SIDE EFFECTS. OUR PROOF-OF-CONCEPT DATA SUPPORT THAT 1) THE GENETICALLY ENGINEERED PROBIOTIC E. COLI NISSLE 1917 STRAINS (ECNL-DOPA) EFFICIENTLY PRODUCE L-DOPA BOTH IN VITRO AND IN VIVO, 2) ORAL DOSING OF ECNL-DOPA READILY COLONIZES THE MOUSE GUT, ACHIEVES A STEADY-STATE PLASMA L-DOPA LEVEL THAT CORRESPONDS TO THE CLINICALLY EFFECTIVE PLASMA LEVEL IN HUMANS, AND INCREASES L-DOPA AND DA/NE LEVELS IN THE BRAIN OF RODENTS AND CANINES, AND 3) ECNL-DOPA TREATMENT LEADS TO IMPROVED NEUROBEHAVIORAL OUTCOMES AND REDUCES ASS LEVELS IN AD ANIMAL MODELS INCLUDING CANINES. THE OVERARCHING GOAL OF OUR PATENT-PENDING ADDP STRATEGY IS TO OPTIMIZE THE LEAD LDBL AND TEST ITS PRECLINICAL EFFICACY IN ALLEVIATING THE COGNITIVE AND BEHAVIORAL DEFICITS, SUCH AS APATHY, OF EARLY AD. TO ACHIEVE THIS GOAL, WE WILL PURSUE THE FOLLOWING SPECIFIC AIMS: (I) OPTIMIZE THE LEAD LDBL FOR ANIMAL TESTING, (II) EVALUATE THE CHRONIC PHARMACOKINETIC (PK), AND SAFETY PROFILE OF THE LEAD LDBLS FOR PRECLINICAL EFFICACY STUDIES, (III) DETERMINE IN VIVO PHARMACODYNAMIC (PD) EFFICACY OF TWO LEAD LDBLS IN TRANSGENIC (TG) AD RODENT MODELS, AND (IV) ASSESS THE EFFICACY OF THE MOST EFFECTIVE LEAD LDBL IN CANINE MODELS OF DEMENTIA. TOGETHER, OUR UNIQUE THERAPEUTIC PIPELINE STRATEGY INVOLVING CHRONIC DELIVERY OF PROBIOTIC L-DOPA IS EXPECTED TO ESTABLISH A NEW LINE OF ENGINEERED MICROBIOME-BASED MONOAMINE NEUROTHERAPEUTIC MODALITIES FOR AD-RELATED DEMENTIAS (ADRD).

LTER: GEORGIA COASTAL ECOSYSTEMS - IV

O-GLYCOSYLATION OF EPIDERMAL GROWTH FACTOR-LIKE MODULES

COORDINATE THE USDA SARE (SUSTAINABLE AGRICULTURE RESEARCH AND EDUCATION) PROGRAM FOR THE 13 STATES AND 2 TERRITORIES OF THE SOUTHERN REGION. EACH AGREEMENT SUPPORTS APPROXIMATELY 12 RESEARCH AND EDUCATION PROJECTS, APPROXIMATELY 10 GRADUATE STUDENT PROJECTS, APPROXIMATELY 10 ON-FARM RESEARCH PROJECTS, APPROXIMATELY 7 FARMER PROJECTS, APPROXIMATELY 7 PDP COMPETITIVE PROJECTS, AND APPROXIMATELY 20 PDP STATE PLANS. REGIONAL COMPETITIVE GRANTS PROGRAM TO HELP AGRICULTURE BECOME MORE PROFITABLE, PROTECT NATURAL RESOURCES AND THE ENVIRONMENT AND IMPROVE QUALITY OF LIFE FOR RURAL COMMUNITIES.

COORDINATE THE USDA SARE (SUSTAINABLE AGRICULTURE RESEARCH AND EDUCATION) PROGRAM FOR THE 13 STATES AND 2 TERRITORIES OF THE SOUTHERN REGION. EACH AGREEMENT SUPPORTS APPROXIMATELY 15 RESEARCH AND EDUCATION PROJECTS, APPROXIMATELY 10 GRADUATE STUDENT PROJECTS, APPROXIMATELY 10 ON-FARM RESEARCH PROJECTS, APPROXIMATELY 7 FARMER PROJECTS, APPROXIMATELY 7 PROFESSIONAL DEVELOPMENT PROGRAM COMPETITIVEPROJECTS, AND APPROXIMATELY 20 PDP STATE PLANS/MODEL STATE PROGRAMS. REGIONAL COMPETITIVE GRANTS PROGRAM TO HELP AGRICULTURE BECOME MORE PROFITABLE, PROTECT NATURAL RESOURCES AND THE ENVIRONMENT AND IMPROVE QUALITY OF LIFE FOR RURAL COMMUNITIES.

INTEGRATED TECHNOLOGY RESOURCE FOR BIOMEDIAL GLYCOMICS

LTER: GEORGIA COASTAL ECOSYSTEMS-III

GEORGIA SEA GRANT OMNIBUS CORE INSTITUTIONAL FUNDING

THE DISSEMINATION OF HEALTHY MARRIAGE AND RELATIONSHIP EDUCATION TO COUPLES ACROSS GEORGIA

LTER: GEORGIA COASTAL ECOSYSTEMS-II

CRISPR CAPTURE AND DESTROY MECHANISMS

COORDINATE THE USDA SARE (SUSTAINABLE AGRICULTURE RESEARCH AND EDUCATION) PROGRAM FOR THE 13 STATES AND 2 TERRITORIES OF THE SOUTHERN REGION. EACH AGREEMENT SUPPORTS APPROXIMATELY 7 RESEARCH AND EDUCATION PROJECTS, APPROXIMATELY 10 GRADUATE STUDENT PROJECTS, APPROXIMATELY 8 ON-FARM RESEARCH PROJECTS, APPROXIMATELY 6 FARMER PROJECTS, APPROXIMATELY 6 PROFESSIONAL DEVELOPMENT PROGRAM TRAINING PROJECTS, AND APPROXIMATELY 20 STATE PLANS/MODEL STATE PROGRAMS. REGIONAL COMPETITIVE GRANTS PROGRAM TO HELP AGRICULTURE BECOME MORE PROFITABLE, PROTECT NATURAL RESOURCES AND THE ENVIRONMENT AND IMPROVE QUALITY OF LIFE FOR RURAL COMMUNITIES.

COMMUNITY TRANSMISSION OF TUBERCULOSIS IN URBAN AFRICA

THE NATIONAL BIOREPOSITORY AND RESOURCE FOR PITUITARY NEUROENDOCRINE TUMOR TRANSLATIONAL RESEARCH (BIOPITNET) - PROJECT SUMMARY PITUITARY NEUROENDOCRINE TUMORS (PITNETS) ARE RARE AND UNDERSTUDIED HETEROGENEOUS TUMORS THAT ARE DETRIMENTAL TO HEALTH CAUSING INCREASED MORTALITY AND POOR QUALITY OF LIFE. CUSHING’S DISEASE (CD) IS A SERIOUS ENDOCRINE DISEASE CAUSED BY AN ADRENOCORTICOTROPIC HORMONE (ACTH)-SECRETING PITNET THAT SUBSEQUENTLY STIMULATES THE ADRENAL GLANDS TO OVERPRODUCE CORTISOL. CHRONIC EXPOSURE TO EXCESS CORTISOL HAS SEVERAL DETRIMENTAL EFFECTS ON HEALTH, INCLUDING INCREASED STROKE RATES, DIABETES, OBESITY, DEPRESSION, ANXIETY, AND A THREEFOLD INCREASE IN THE RISK OF DEATH FROM CARDIOVASCULAR DISEASE AND CANCER. DESPITE DECADES OF RESEARCH, CURRENT TREATMENTS FOR CD REMAIN SUBOPTIMAL, AND THE DEVELOPMENT OF TARGETED THERAPIES IS CHALLENGING DUE TO THE LIMITED KNOWLEDGE OF PITNET TUMOR CELLULAR AND MOLECULAR COMPLEXITY. THE RC2 WILL FUND THE NATIONAL BIOREPOSITORY AND RESOURCE FOR PITUITARY NEUROENDOCRINE TUMOR TRANSLATIONAL RESEARCH (BIOPITNET) WHICH WILL BE AN OPEN SOURCE, CLINICALLY RELEVANT DEEP TUMOR PHENOTYPING PLATFORM AND BIOREPOSITORY. THIS IS THE FIRST PHASE OF A CONTIN- UUM OF TRANSLATIONAL- AND HYPOTHESIS-DRIVEN RESEARCH THAT WILL ACCELERATE THE DEVELOPMENT OF EFFECTIVE THERAPIES FOR PITNETS, PREVENTING TUMOR RECURRENCES AND IMPROVING REMISSION RATES AND QUALITY OF LIFE FOR PATIENTS. THE BIOPITNET TEAM WILL: 1) ESTABLISH A LARGE-SCALE UNIQUE RESOURCE WITHIN AN INFRASTRUCTURE THAT WILL GENERATE SUS- TAINABLE NOVEL RESEARCH TOOLS BENEFITING INVESTIGATORS WITH FOCUSED TRANSLATIONAL RESEARCH OF PITNETS, AND 2) IMPLEMENT INTERDISCIPLINARY APPROACHES AND EXPERTISE TO GENERATE A RESOURCE THAT WILL FOSTER TRANSLATIONAL AND HYPOTHESIS-DRIVEN RESEARCH IN PITNET DISEASES. THE REGISTRY FOR ADENOMAS OF THE PITUITARY AND RELATED DISOR- DERS (RAPID) IS A TWELVE CENTER US CONSORTIUM FOUNDED IN 2021 TO IMPROVE TREATMENT OF PATIENTS WITH PITNETS AND FUNDED BY GRATEFUL PATIENTS. THE BIOPITNET LEVERAGES THE RAPID CONSORTIUM CLINICAL PLATFORM TO COMBINE CLINICAL ANNOTATIONS OF FUTURE PROSPECTIVELY ENROLLED PATIENTS WITH MOLECULAR AND PATHOLOGICAL INFORMATION USING STATE-OF-THE-ART PRECLINICAL MODELS. THE LOW INCIDENCE OF CD REQUIRES MULTICENTER COLLABORATION AND INTERDISCIPLI- NARY TEAM SCIENCE PARTNERSHIPS BETWEEN BASIC- AND CLINICIAN-TRANSLATIONAL SCIENTISTS COMPRISING THE EXPERTISE OF PROFESSIONALS TRAINED IN COMPLIMENTARY FIELDS INCLUDING MEDICAL AND SURGICAL TREATMENT, NEUROPATHOLOGY, MOLEC- ULAR GENETICS OF PITNETS, MOLECULAR PATHOLOGY AND HIGH-PLEX SPATIAL IMAGING, ORGANOID AND IPSC TECHNOLOGY, CANINE COMPARATIVE ONCOLOGY DISEASE MODELS AND TRANSLATIONAL BIOINFORMATICS. THE BIOPITNET WILL BE ESTAB- LISHED BY THE SUCCESSFUL COMPLETION OF AIM 1: TO ESTABLISH THE BIOPITNET CENTRALIZED BIOREPOSITORY COMPRISING OF RESOURCES THAT WILL BE BENCHMARKED TO THE PATIENTS’ PITNET TISSUE OF ORIGIN, AIM 2: TO DEVELOP A PITNET CLINICALLY RELEVANT CLASSIFICATION SYSTEM FOR CD, AND AIM 3: TO ESTABLISH A BIOBANK OF INDUCED PLURIPOTENT STEM CELL (IPSCS) LINES GENETICALLY ENGINEERED TO MODEL CORTICOTROPH SUBTYPE PITNETS AS A RESOURCE FOR INVESTIGATING GENETIC UNDERLYING MECHANISMS OF CD.

SUSTAINABLE AGRICULTURE RESEARCH AND EDUCATION (SARE) PROGRAM

GLYGEN GROWTH AND EVOLUTION INTO A CENTRAL RESOURCE FOR GLYCANS AND GLYCOCONJUGATES - ABSTRACT GLYGEN IS A MATURING (FIVE YEARS OLD) KNOWLEDGEBASE THAT ACCUMULATES DATA IN THE GLYCOBIOLOGY DOMAIN AND CONNECTS IT WITH OTHER DATA TYPES. GLYGEN IS UNIQUE; NO OTHER PRESENT OR PRIOR INFORMATIC RESOURCE HAS UNDERTAKEN SUCH AN INTEGRATIVE MISSION. IN PART, THE LAGGING GROWTH OF ACCESSIBLE KNOWLEDGE IN THE GLYCOBIOLOGY DOMAIN, COMPARED TO OTHER -OMICS OR BIOMEDICAL RESEARCH FIELDS, REFLECTS THE INHERENT COMPLEXITY OF GLYCAN STRUCTURES, WHICH, UNLIKE GENES AND PROTEINS, EXIST IN BRANCHED AND ISOMERIC FORMS WHOSE BIOSYNTHESIS IS NOT ATTRIBUTABLE TO WELL-CHARACTERIZED, TEMPLATE-DRIVEN PROCESSES SUCH AS TRANSCRIPTION OR TRANSLATION. RATHER, GLYCAN BIOSYNTHESIS IS MEDIATED BY THE REGULATED EXPRESSION OF ENSEMBLES OF GLYCOSYLTRANSFERASES, SUBSTRATE TRANSPORTERS, AND SECRETORY PATHWAY REGULATORY MECHANISMS THAT TOGETHER GENERATE DYNAMIC CELL- AND TISSUE-SPECIFIC PATTERNS OF PROTEIN AND LIPID GLYCOSYLATION. IN ADDITION, EACH GLYCOSYLATION SITE ON A GLYCOPROTEIN MAY ROUTINELY BE MODIFIED BY ONE OF AN ENSEMBLE OF GLYCAN STRUCTURES, A GLYCOPROTEIN FEATURE CALLED MICROHETEROGENEITY. IMPORTANTLY, MICROHETEROGENEITY IS NOT RANDOM, BUT REFLECTS THE INTRINSIC BIOSYNTHETIC CAPACITY OF SPECIFIC CELLS AND TISSUES AND MAY BE MODIFIED BY DISEASE. THESE STRUCTURAL AND BIOSYNTHETIC COMPLEXITIES ARE ESSENTIAL CONTRIBUTORS TO THE TISSUE- AND DISEASE-SPECIFIC FUNCTIONS OF GLYCANS AND GLYCOSYLATION, AND, THEREFORE, NEED TO BE CAPTURED AND REPRESENTED IN KNOWLEDGEBASES IN A WAY THAT THEY CAN BE QUERIED AND LINKED TO OTHER TYPES OF DATA. GLYGEN AIMS TO EXPAND ITS UNDERLYING DATA MODEL TO ACCOMMODATE NEW AND MORE COMPLEX DATATYPES, AUGMENTING AND INTEGRATING NEW DATA TYPES, AND IMPLEMENTING ROBUST MODELING, UNIFIED PROCEDURES, AND TOOLS TO IMPROVE DISCOVERY AND EXPLORATION OF GLYCAN AND GLYCOCONJUGATE DATA. ENHANCEMENT OF THE OVERALL RESOURCE FUNCTIONALITY WILL BE ACHIEVED THROUGH FRONT-END IMPROVEMENTS TO ACCOMMODATE USER PREFERENCES AND ENSURE EXCEPTIONAL DATA COMMUNICATION AND VISUALIZATION. IMPROVING THE INTERCONNECTIVITY OF GLYGEN AND ITS PARTNER DATABASES AS WELL AS ENHANCING DATA-SHARING ACROSS RESOURCES WILL CONTINUE TO BE CORE PRINCIPLES OF THE GLYGEN PROJECT. ALL RESULTING HARMONIZED DATA WILL BE AVAILABLE THROUGH HIGHLY PERMISSIVE LICENSES FOR EASY INTEGRATION INTO OTHER RESOURCES, SUCH AS NCBI, EBI, SIB AND OTHER INTERNATIONAL EFFORTS, AS WELL AS FOR EASY REPURPOSING BY INDEPENDENT RESEARCHERS, EDUCATORS, BIOINFORMATICIANS, AND COMMERCIAL ENTITIES. BY THE END OF THE NEXT PROJECT PERIOD GLYGEN EXPECTS TO BECOME THE GO-TO, WELL-INTEGRATED RESOURCE FOR GLYCOSCIENCE DATA, SIMILAR TO EXISTING PROTEIN AND GENOMIC RESOURCES AND SERVING THE SAME BROAD COMMUNITY OF BIOMEDICAL RESEARCHERS.

ANALYSIS OF METABOLIC CAPABILITIES OF PROKARYOTIC CELLS

METHODS AND MECHANISMS IN CARBOHYDRATE CHEMISTRY

TUMOR GLYCOMICS LABORATORY FOR DISCOVERY OF PANCREATIC CANCER MARKERS

A NATIONAL GLYCOSCIENCE RESOURCE - CCRC SERVICE AND TRAINING

2014 OMNIBUS PROPOSALS - GEORGIA SEA GRANT COLLEGE PROGRAM

MULTIPLEX TREATMENT OUTCOMES TEST FOR CHAGAS DISEASE

GEORGIA SEA GRANT COLLEGE PROGRAM MARINE RESOURCES UTILIZATION IN GEORGIA 2010

SUSTAINABLE AGRICULTURE RESEARCH AND EDUCATION (SARE) PROGRAM

EXPLOITATION OF GENETIC AND EPIGENETIC VARIATION IN THE REGULATION OF TOMATO FRUIT QUALITY TRAITS

STRENGTHENING THE STEM PIPELINE IN THE PEACH STATE: RECRUITMENT, RETENTION AND RESEARCH (NEW ALLIANCE)

FUNCTIONAL GENOMICS OF MAIZE CENTROMERES

SUSTAINABLE AGRICULTURE RESEARCH AND EDUCATION (SARE) PROGRAM

APPLYING ENGINEERING WITH NATURE (EWN) TECHNIQUES, APPROACHES AND PRACTICE ON A REGIONAL SCALE

NSF CONVERGENCE ACCELERATOR TRACK I: SPHERICITY -- CIRCULARITY FROM MOLECULES TO THE BUILT ENVIRONMENT IN COMMUNITIES -THIS PROJECT AIMS TO OPTIMIZE CIRCULARITY, FROM THE CITY UP, TRANSFORMING THE LINEAR CONSUMPTION MODEL OF RAW MATERIAL EXTRACTION, PRODUCTION, USE, AND DISPOSAL THAT DOMINATES THE GLOBAL ECONOMY. THIS LINEAR MODEL HAS LED TO SERIOUS UNINTENDED WORLDWIDE ISSUES, FROM POLLUTION TO RESOURCE DEPLETION. THIS PROJECT WILL REIMAGINE HOW WE DESIGN, FROM MOLECULES AND MATERIALS TO BUILDINGS AND COMMUNITIES. THE NEWLY UPDATED AND EXPANDED CIRCULARITY ASSESSMENT PROTOCOL (CAP) FRAMEWORK WILL BE CO-IMPLEMENTED WITH 11 CITIES. CAP INTEGRATES THE OPEN DATA TOOL DEBRIS TRACKER WITH DATA FREELY AVAILABLE, JOINING DATA FROM NEARLY 100 COUNTRIES AROUND THE WORLD. THE NEW PORTAL FOR THIS PROJECT WILL HOUSE THE DATA FROM PHASE I AND PHASE II COMMUNITIES AIMING TO FOSTER GLOBAL DIALOGUE ABOUT COMMUNITY CIRCULARITY AND CREATING MEANINGFUL CHANGE. TO INCREASE CIRCULARITY, THE RESEARCHERS WILL HELP COMMUNITIES ADDRESS SYSTEMIC AND INTERSECTIONAL ISSUES, INCLUDING POLLUTION BURDENS, LACK OF INFRASTRUCTURE, AND LACK OF ACCESS TO SERVICES. THE PROJECT WILL FURTHER DEVELOP A PLATFORM FOR UNDERREPRESENTED VOICES THROUGH AN EXISTING PODCAST CALLED AQUATHREAD, PRODUCED AND RECORDED AT WUGA, THE UNIVERSITY OF GEORGIA?S NPR AFFILIATE. THIS RESEARCH WILL CONTINUE TO INCREASE PUBLIC SCIENTIFIC LITERACY AND ENGAGEMENT WITH SCIENCE AND TECHNOLOGY THROUGH THE USE OF OPEN DATA AND FREE MOBILE CITIZEN SCIENCE APPS; IMPROVE THE WELL-BEING OF INDIVIDUALS IN SOCIETY BY REDUCING WASTE AND IMPROVING THE BUILT ENVIRONMENT; AND DEVELOP A DIVERSE, GLOBALLY COMPETITIVE WORKFORCE. ALL COMMUNITIES, PARTNERS, AND THE PUBLIC WILL HAVE ACCESS TO PROJECT DATA, FACILITATING THE USE OF SCIENCE AND TECHNOLOGY TO INFORM PUBLIC POLICY AND SUPPORT DECISION-MAKING. IN CONTRAST TO THE LINEAR ECONOMY OF ?TAKE, MAKE, WASTE?, CIRCULAR ECONOMY (CE) DECOUPLES ECONOMIC GROWTH FROM RESOURCE CONSUMPTION. CE PRINCIPLES ARE BASED ON THE EFFICIENT USE OF RESOURCES AND ELIMINATING WASTE FROM PRODUCT LIFE CYCLES. THIS PROJECT WILL TACKLE THE COMPLEX CHALLENGES THAT CURRENTLY INHIBIT THE CIRCULAR ECONOMY?S GROWTH BY DEEPLY INTEGRATING DIVERSE DISCIPLINES THROUGH THE RESEARCHERS? PROVEN HOLISTIC SYSTEMS FRAMEWORK. IN PHASE II, THE NEWLY UPDATED AND EXPANDED CIRCULARITY ASSESSMENT PROTOCOL (CAP) FRAMEWORK WILL BE USED TO CONVERGE CIRCULARITY ACROSS PLASTICS (EXPLORING POLYFLUOROALKYL SUBSTANCE-FREE ALTERNATIVES), ORGANIC MATERIALS, AND THE BUILT ENVIRONMENT IN 11 CITIES. IN PHASE I OF THIS PROJECT, A CIRCULARITY PATH WAS CONNECTED AND CONVERGED ACROSS MULTIPLE MATERIALS AND SCALES IN TWO LARGE METROPOLITAN AREAS. PHASE II WILL EXPAND THIS WORK BY TRAINING LOCAL IMPLEMENTATION PARTNERS, AND FURTHER DEVELOPING A NOVEL DYNAMIC DATA AND EDUCATION PORTAL. THIS PORTAL WILL INCLUDE CITY AND METADATA DASHBOARDS TO FACILITATE INTER- AND INTRA-COMMUNITY DIALOGUE TO CREATE SYSTEMS CHANGE. PROJECT PARTNERS INCLUDE THE RESILIENT CITIES NETWORK, A CITY-LED NETWORK THAT BRINGS TOGETHER OVER 200 CHIEF RESILIENCE OFFICERS, PRACTITIONERS, AND RESEARCHERS; THE 2030 DISTRICTS NETWORK OF CITIES WORKING TO CATALYZE TRANSFORMATION IN THE BUILT ENVIRONMENT TO MITIGATE THE EFFECTS OF CLIMATE CHANGE; MISSISSIPPI RIVER CITIES AND TOWNS INITIATIVE MAYORS; AND THE UPPER MIDWEST ASSOCIATION FOR CAMPUS SUSTAINABILITY (UMACS). THIS NETWORK OF NETWORKS IS THE NEXT STEP IN EXPANDING THIS PROJECT INTO A SUSTAINABLE FUTURE AS A CONTINUED RESOURCE AND PLATFORM FOR SHARING AMONGST CITIES AROUND THE WORLD CATALYZING CHANGE. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE PLANNED FOR THIS AWARD.

NATIONAL STEM TEACHER CORPS PILOT PROGRAM: STRENGTHENING GEORGIA SCIENCE TEACHERS THROUGH A TEACHING CORPS, MENTORING, AND LEADERSHIP DEVELOPMENT -THE NATIONAL STEM TEACHER CORPS PILOT PROGRAM REGIONAL ALLIANCE PROJECT AIMS TO RECOGNIZE OUTSTANDING STEM EDUCATORS IN HIGH-NEED SCHOOLS THAT ADVANCE EDUCATIONAL EXCELLENCE IN THE SOUTHERN REGION. THIS PROJECT WILL SUPPORT 12 STEM TEACHER CORPS MEMBERS BY RECOGNIZING AND REWARDING THEIR ACCOMPLISHMENTS AND EFFORT TO ENHANCE STEM TEACHING AND LEARNING IN K ? 12 SCIENCE EDUCATION. THE REGIONAL ALLIANCE AIMS TO ADDRESS THE SHORTAGE OF SCIENCE TEACHERS BY IDENTIFYING SCIENCE TEACHERS WHO DEMONSTRATE EXCEPTIONAL SCIENCE INSTRUCTION, BUILDING A MENTOR NETWORK TO SUPPORT AND RETAIN NEW SCIENCE TEACHERS, AND ARTICULATING LEADERSHIP PATHWAYS FOR EXPERIENCED SCIENCE TEACHERS THE PROJECT WILL ALSO PROVIDE PROFESSIONAL DEVELOPMENT, MENTORSHIP AND SUPPORT DIRECTLY TO MORE THAN 100 OTHER STEM TEACHERS WITHIN THE REGION THROUGH THE USE OF HUBS THAT WILL BUILD AND STRENGTHEN EXISTING CONNECTIONS BETWEEN THE DIFFERENT PARTICIPATING ORGANIZATIONS TO IMPACT THE SCIENCE TEACHING COMMUNITY. THE ALLIANCE WILL CONSIST OF THREE HUBS. HUB STEM TEACHER CORPS WILL IDENTIFY AND SUPPORT 12 GEORGIA-BASED STEM TEACHER CORPS TEACHERS WHO WILL CONTRIBUTE AND WORK WITHIN THE OTHER TWO HUBS. HUB CAPACITY BUILDING WILL ORGANIZE ESTABLISHED LEARNING OPPORTUNITIES INTO NEW PROGRAMMING THAT TARGETS NEWLY HIRED SCIENCE TEACHERS AND BUILDS THE MENTORING EXPERTISE OF EXPERIENCED SCIENCE TEACHERS. HUB EMPOWER WILL CURATE SUPPORT AND LEADERSHIP PROGRAMMING FOR SCIENCE TEACHERS ACROSS GEORGIA. THE HUBS WILL REACH EVERY K-12 SCIENCE TEACHER IN GEORGIA AND EASILY INVOLVE SCIENCE TEACHERS FROM ACROSS THE STATE. STRATEGICALLY ENGAGING MORE SCIENCE TEACHERS IN VARIOUS CONNECTED LEARNING OPPORTUNITIES WILL ENHANCE THE WORK OF GEORGIA'S SCIENCE TEACHERS. GEORGIA'S STUDENTS WILL BENEFIT FROM A STRENGTHENED SCIENCE TEACHING NETWORK BY EXPERIENCING SCIENCE INSTRUCTION THAT ENHANCES THEIR KNOWLEDGE AND PREPARES THEM TO BE INFORMED CITIZENS AND FOR SCIENCE OR RELATED CAREERS. ?? THIS REGIONAL ALLIANCE AT GEORGIA TECH INCLUDES PARTNERSHIPS WITH GEORGIA DEPARTMENT OF EDUCATION ? SCIENCE DIVISION (GADOE), GEORGIA SCIENCE TEACHERS ASSOCIATION (GSTA), GEORGIA SCIENCE SUPERVISORS ASSOCIATION (GSSA), GEORGIA YOUTH SCIENCE AND TECHNOLOGY CENTER (GYSTC), REGIONAL EDUCATION SERVICE AGENCIES (RESA) AND SEVERAL GEORGIA SCHOOLS AND SCHOOL DISTRICTS. THIS PROJECT HAS THREE GOALS: 1) IDENTIFY AND DRAW UPON THE EXPERTISE OF GEORGIA STEM TEACHER CORPS MEMBERS; 2) EMPOWER CURRENT AND EMERGING SCIENCE TEACHER LEADERS; AND 3) BUILD AND SUSTAIN SCIENCE TEACHER LEARNING NETWORKS. TO ACCOMPLISH THESE GOALS AND ENSURE IMPACT OF THE PROJECT, THERE WILL BE AN EXECUTIVE COMMITTEE CONSISTING OF HUB LEADERS AND PROJECT DIRECTORS AND AN ADVISORY COMMITTEE COMPRISED OF LOCAL AND NATIONAL EXPERTS, AND AN EXTERNAL EVALUATOR WILL MONITOR THE PROJECT'S PROCESS AND PRODUCTIVITY. THE HUB-BASED RESEARCH QUESTIONS WILL CONTRIBUTE TO AN UNDERSTANDING OF HOW: 1) A DISTRIBUTED LEADERSHIP APPROACH ENHANCES THE SCIENCE EDUCATION COMMUNITY, 2) SCIENCE TEACHERS ARE SUPPORTED THROUGH AN ALLIANCE TO BUILD THEIR EXPERTISE AND RESILIENCE, AND 3) ALLIANCES CAN CONTRIBUTE TO ELEVATING THE SCIENCE TEACHING PROFESSION. THE ONGOING ANALYSIS OF DATA WITHIN EACH HUB WILL IMPROVE THE PRODUCTS OF THE HUBS AND PROVIDE INSIGHTS INTO RETAINING TEACHERS AND STRENGTHENING TEACHING SYSTEMS. THIS REGIONAL ALLIANCE PROJECT IS SUPPORTED THROUGH THE NATIONAL STEM TEACHER CORPS PILOT PROGRAM. THE NSF NATIONAL STEM TEACHER CORPS PILOT PROGRAM SUPPORTS OUTSTANDING STEM EDUCATORS IN HIGH-NEED SCHOOLS THAT ADVANCE EDUCATIONAL EXCELLENCE IN OUR NATION?S PREK-12 CLASSROOMS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE PLANNED FOR THIS AWARD.

EXPANDING MILITARY INSTALLATION AND DEFENSE COMMUNITY-BASED CAPACITY FOR APPLIED RESEARCH APPLICATION IN SUPPORT OF THE NETWORK FOR ENGINEERING WITH NATURE

**AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** SINCE ITS FIRST DETECTION IN 2008, SPOTTED-WING DROSOPHILA (SWD),DROSOPHILA SUZUKII(MATSUMURA), HAS BECOME A KEYSTONE PEST OF SMALL- AND STONE-FRUITS IN THE UNITED STATES VALUED AT $5.8 BILLION. OUR TEAM MADE SUBSTANTIAL PROGRESS BY REFINING MONITORING TOOLS, DEVELOPING EFFECTIVE INSECTICIDE-BASED MANAGEMENT PROGRAMS, CULTURAL CONTROLS, AND SCREENING NATIVE AND EXOTIC BIOLOGICAL CONTROL AGENTS TO ADDRESS THE CRISIS PHASE OF SWD INVASION. HOWEVER, SWD MANAGEMENT IS STILL HIGHLY INSECTICIDE-DEPENDENT AND IS FURTHER CHALLENGED BY SECONDARY PEST OUTBREAKS, INSECTICIDE RESISTANCE, AND INCREASED INPUT COSTS. NOW THAT SWD IS ESTABLISHED AS A KEYSTONE PEST IN THE U.S., IT IS CRITICAL TO DEVELOP MORE SUSTAINABLE STRATEGIES TO MANAGESWD. THUS,GOAL OF THIS PROJECT IS TO IMPLEMENT SYSTEMS-BASED INTEGRATED MANAGEMENT PROGRAMS THAT ARE COST-EFFECTIVE AND ENVIRONMENTALLY-SUSTAINABLE FOR LONG-TERM MANAGEMENT OF SWD. MAJOR OBJECTIVES OF THIS PROJECT INCLUDE: 1) IMPLEMENTATION OF BEST MANAGEMENT PROGRAMS FOR SUSTAINABLE SWD MANAGEMENT IN COLLABORATION WITH GROWER INFLUENCERS;2)DEVELOP ECONOMICS-BASED DECISION AID TOOLS TO INCREASE PROFITABILITY; 3) EVALUATE SUSTAINABLE ALTERNATIVES TO INSECTICIDES FOR LONG-TERM SWD MANAGEMENT;4) ASSESS AND REDUCE THE RISK OF INSECTICIDE RESISTANCE DEVELOPMENT; AND 5)DEVELOP AND DISSEMINATE ACTIONABLE RECOMMENDATIONS THAT ENABLE PRODUCERS TO OPTIMIZE PEST MANAGEMENT DECISIONS, AND EVALUATE THEIR IMPACT.THIS STAKEHOLDER-DRIVEN TRANSDISCIPLINARY PROJECT ADDRESSES SCRI PROGRAM FOCUS AREAS: 2) PEST MANAGEMENT; 3) PLANT PRODUCTION AND PRODUCTION EFFICIENCY; 4) NEW INNOVATIONS AND TECHNOLOGY; AND 5) FOOD SAFETY. GROWER-STAKEHOLDERS WERE ENGAGED TO DEVELOP OBJECTIVES OF THIS PROPOSAL AND WILL CONTINUE TO PLAY CENTRAL ROLE THROUGH STAKEHOLDER ADVISORY BOARD, AND CROP- AND REGION-SPECIFIC GROWER INFLUENCER TEAMS.

PURPOSE: WITH OVER 368,000 ACRES OF EXPANSIVE SALT MARSHES, GEORGIA IS HOME TO ONE OF THE MOST PRODUCTIVE SALT-MARSH-TIDAL CREEK ECOSYSTEMS. THESE MARSHES AND CREEKS PROVIDE A WEALTH OF BENEFITS LIKE MAINTAINING HEALTHY WATER, PROTECTING US FROM FLOODING AND EROSION, PROVIDING NURSERY AND CRITICAL HABITAT FOR FLORA AND FAUNA, CARBON SEQUESTRATION, AND SUPPORTING A RANGE OF RECREATION AND COMMERCIAL ACTIVITIES. GEORGIA'S BARRIER ISLANDS ARE ALSO HOME TO THE GULLAH-GEECHEE PEOPLE WHO ARE DESCENDANTS OF ENSLAVED AFRICANS FROM PLANTATIONS ALONG THE LOWER ATLANTIC COAST. THE STATE ALSO HAS A LONG HISTORY OF GLOBAL TRADE AND HOUSES THE 4TH LARGEST PORT IN THE COUNTRY, WITH DEEPWATER PORTS LOCATED IN SAVANNAH AND BRUNSWICK. ALL OF ITS ASSETS - THE EXPANSIVE SALT-MARSH ECOSYSTEMS, THE PEOPLE WHO LIVE OR WORK IN THE COASTAL ZONE, AND THE INFRASTRUCTURE THAT KEEPS ECOSYSTEMS AND PEOPLE HEALTHY IS UNDER THREAT FROM INCREASING RISKS OF FLOODING, SEA LEVEL RISE, STORM SURGE AS WELL AS POPULATION GROWTH AND DEVELOPMENT. MARINE EXTENSION AND GEORGIA SEA GRANT'S MISSION IS TO IMPROVE THE ENVIRONMENTAL, SOCIAL, AND ECONOMIC HEALTH OF GEORGIA'S COAST THROUGH RESEARCH, EDUCATION, AND EXTENSION. THROUGH A COMPREHENSIVE STRATEGIC PLANNING PROCESS, MARINE EXTENSION AND GEORGIA SEA GRANT HAS DEVELOPED A STRATEGIC PLAN TO GUIDE ITS ACTIVITIES FROM 2024-2027. OVER THE PERIOD OF FOUR YEARS, THE PROGRAM WILL LEVERAGE THE EXPERTISE OF SCIENTISTS AND STUDENTS AT VARIOUS INSTITUTIONS OF HIGHER EDUCATION IN GEORGIA TO GENERATE SCIENCE-BASED SOLUTIONS TO CRITICAL ISSUES, AND ENGAGE ARTISTS AND SCHOLARS IN HUMANITY TO PROVIDE CREATIVE INSIGHTS INTO THE CULTURE, HISTORY, GEOGRAPHY, AND ENVIRONMENTAL ISSUES IN GEORGIA. THE PROGRAM WILL FOSTER THE DEVELOPMENT OF AN INNOVATIVE STEAM (SCIENCE, TECHNOLOGY, ENGINEERING, ARTS, AND MATHEMATICS) WORKFORCE BY PROVIDING RESEARCH, TRAINING, AND PROFESSIONAL DEVELOPMENT OPPORTUNITIES TO STUDENTS, SCIENTISTS, ARTISTS, AND SCHOLARS. MARINE EXTENSION AND GEORGIA SEA GRANT SERVES AS A BRIDGE, CONNECTING DIVERSE SHAREHOLDERS TO FACILITATE CHANGE IN A COMPLEX SOCIAL AND ECONOMIC ENVIRONMENT. SEA GRANT ALSO PROVIDES A NETWORK FOR SHARING INFORMATION AND KNOWLEDGE, BOTH LOCALLY AND AT REGIONAL AND NATIONAL LEVELS. AS A RESULT OF ITS RESEARCH, EDUCATION, AND OUTREACH EFFORTS, MARINE EXTENSION AND GEORGIA SEA GRANT ENVISIONS AN ENGAGED AND INFORMED PUBLIC THAT SUPPORTS THRIVING COASTAL ECOSYSTEMS AND RESILIENT AND INCLUSIVE COMMUNITIES.

THE US GREENHOUSE INDUSTRY INCLUDING FLORICULTURE AND GREENHOUSE VEGETABLES HAD A 2015 FARM GATE VALUE OF ~$6.5 BILLION. IN GREENHOUSES MOST ENVIRONMENTAL VARIABLES CAN BE CONTROLLED TO PROVIDE OPTIMAL CONDITIONS FOR PLANT GROWTH. LIGHT TYPICALLY IS LESS CONTROLLED THAN OTHER ENVIRONMENTAL CONDITIONS WHICH CAN RESULT IN SIGNIFICANT VARIABILITY IN LIGHT LEVELS AND THUS CROP YIELD AND QUALITY. THE VARIABILITY CAN BE SPATIAL SPECTRAL AND TEMPORAL AND OCCURS ON SHORT (WITHIN A DAY) INTERMEDIATE (DAY-TO-DAY) AND LONG (SEASONAL) TIME SCALES. FOR EFFICIENT YEAR-ROUND PRODUCTION IN GREENHOUSES SUPPLEMENTAL LIGHT IS OFTEN BENEFICIAL BUT THE EXPENSES CAN BE HIGH. THE ELECTRICITY REQUIRED FOR SUPPLEMENTAL LIGHTING IN GREENHOUSES ACCOUNTS FOR 20-30% OF VARIABLE COSTS. SINCE TYPICAL GREENHOUSE PROFIT MARGINS ARE 1-5% MORE COST-EFFECTIVE LIGHTING STRATEGIES CAN HAVE A MAJOR IMPACT ON THE PROFIT MARGIN. PLANT FACTORIES AN EMERGING TECHNOLOGY WHERE PLANTS ARE GROWN INDOORS PROVIDE TOTAL CONTROL OVER ENVIRONMENTAL CONDITIONS BUT PRODUCTION RELIES ENTIRELY ON ELECTRIC LIGHTING ACCOUNTING FOR 50-60% OF THE VARIABLE COSTS. CLEARLY MORE COST-EFFECTIVE LIGHTING APPROACHES WILL HAVE A MAJOR IMPACT ON THE SUSTAINABILITY AND PROFITABILITY OF CONTROLLED ENVIRONMENT AGRICULTURE (GREENHOUSES AND PLANT FACTORIES) REDUCE ENERGY USE AND GREENHOUSE GAS EMISSIONS AND THUS ALSO PROVIDE SOCIETAL AND ENVIRONMENTAL BENEFITS.THERE HAS BEEN LITTLE PAST RESEARCH ON OPTIMIZING THE ECONOMIC RETURN OF SUPPLEMENTAL LIGHTING PRACTICES FOR GREENHOUSE PRODUCTION (FLORICULTURE AND VEGETABLES) AND MOST PAST WORK HAS FOCUSED ON HIGH-PRESSURE SODIUM (HPS) LIGHTS. LIGHT-EMITTING DIODE (LED) LIGHTS ARE GRADUALLY BECOMING CHEAPER AND MORE EFFICIENT AND ARE INCREASINGLY BEING USED INSTEAD OF HPS LIGHTS. HOWEVER LED LIGHTS ARE MORE EXPENSIVE TO INSTALL THAN HPS LIGHTS SO TO JUSTIFY THE CAPITAL EXPENSE LED LIGHTS NEED TO PROVIDE ADDITIONAL VALUE COMPARED TO HPS. THAT VALUE CAN COME FROM LOWER OPERATING COSTS HIGHER YIELDS BETTER QUALITY OR THE PRODUCTION OF HIGHER VALUE SPECIALTY CROPS.LED LIGHTS PROVIDE IMPORTANT NEW OPPORTUNITIES TO INCREASE THE COST-EFFECTIVENESS OF LIGHTING BECAUSE BOTH THE SPECTRUM AND LIGHT INTENSITY CAN BE ACCURATELY CONTROLLED. THIS CAN GIVE GROWERS BETTER CONTROL OVER CROP GROWTH AND QUALITY. HOWEVER CURRENT LED GROW LIGHTS DO NOT TAKE ADVANTAGE OF THE ABILITY TO PRECISELY CONTROL LIGHT INTENSITY AND SPECTRUM IN REAL TIME. WE WILL HELP GROWERS GET MORE VALUE OUT OF THEIR LIGHTING SYSTEM BY PROVIDING HORTICULTURAL AND ECONOMICAL INFORMATION AND TOOLS TO MANAGE THE LIGHTS FOR OPTIMAL CROP GROWTH AND QUALITY.THE ELECTRICAL COST ASSOCIATED WITH LIGHTING OFTEN IS THE SECOND LARGEST VARIABLE COST IN GREENHOUSES AFTER LABOR AND ARE THE BIGGEST COST IN PLANT FACTORIES. INCREASING THE COST-EFFECTIVENESS OF LIGHTING WILL LOWER PRODUCTION COSTS AND/OR INCREASE THE VALUE OF THE CROP (BY INCREASING QUALITY OR YIELD) WHICH CAN INCREASE THE MARGINS AND PROFITABILITY OF CONTROLLED ENVIRONMENT AGRICULTURE.WE WILL HELP GROWERS MAKE BETTER LIGHTING DECISIONS. SPECIFICALLY WE WILL: 1) DEVELOP TOOLS TO DETERMINE WHETHER SUPPLEMENTAL LIGHTING IS COST-EFFECTIVE FOR DIFFERENT LOCATIONS AND PRODUCTION SYSTEMS 2) DECIDE WHETHER HPS OR LED LIGHTS ARE MORE COST-EFFECTIVE FOR A GIVEN APPLICATION AND 3) DEVELOP GUIDELINES TO HELP GROWERS GET THE MOST VALUE OUT OF SUPPLEMENTAL LIGHTING BY MINIMIZING OPERATING COSTS AND/OR MAXIMIZING CROP QUALITY. WE WILL DEVELOP MODELS THAT CONSIDER CROP PHYSIOLOGICAL PARAMETERS CROP VALUE THE DESIGN AND CAPITAL COSTS OF THE LIGHTING SYSTEM REAL-TIME ELECTRICITY PRICING AND CURRENT AND FORECASTED LIGHT LEVELS. THESE MODELS WILL BE USED TO DEVELOP STRATEGIES TO PROVIDE SUPPLEMENTAL LIGHT IN THE MOST COST-EFFECTIVE WAY POSSIBLE. WE WILL ALSO DEVELOP HARDWARE AND SOFTWARE TOOLS TO HELP GROWERS IMPLEMENT THESE LIGHTING STRATEGIES BASED ON CROP NEEDS AND SPECIFIC GROWING SYSTEMS. THE RETURN ON INVESTMENT OF THESE LIGHTING STRATEGIES WILL BE EVALUATED TO DETERMINE THE COST-EFFECTIVENESS OF SUPPLEMENTAL LIGHTING.A COMPREHENSIVE OUTREACH PLAN WILL ENSURE THAT PROJECT FINDINGS ARE DISSEMINATED IN DIFFERENT FORMS TO REACH THE GROWERS AND ASSOCIATED CEA INDUSTRIES. OUTREACH EFFORTS WILL INCLUDE A WEBSITE WEBINARS PRESENTATIONS ONLINE ARTICLES TRADE JOURNAL ARTICLES EXTENSION VISITS AND PEER-REVIEWED JOURNAL ARTICLES. INDUSTRY MEMBERS WILL BE SURVEYED TO DETERMINE HOW THEY PREFER TO RECEIVE INFORMATION ALLOWING US TO FINE-TUNE OUR OUTREACH METHODS. BEYOND SIMPLY SHARING RESEARCH RESULTS THE DECISION-MAKING TOOLS WE DEVELOP WILL DIRECTLY ASSIST INDUSTRY MEMBERS AND ALLOW DIRECT IMPLEMENTATION OF THESE RESEARCH RESULTS. WE WILL DEVELOP DECISION SUPPORT SOFTWARE TO ENABLE GROWERS TO ASSESS WHETHER USE OF SUPPLEMENTAL LIGHTING (AND TO WHAT DEGREE) IS ECONOMICAL GIVEN THEIR CROPS AND GEOGRAPHIC LOCATION. IF LIGHTING IS DEEMED PROFITABLE THE TOOLS CAN BE USED TO DETERMINE WHETHER HPS OR LED LIGHTS ARE MORE COST-EFFECTIVE BASED ON THE TYPE OF FACILITY PATTERNS OF LIGHTING USE AND ELECTRICITY COST. VIRTUAL GROWER A FREELY-AVAILABLE USDA-ARS GREENHOUSE SIMULATION TOOL WILL BE UPGRADED TO INCLUDE SIMULATIONS OF DIFFERENT LIGHTING SCENARIOS. THESE TOOLS WILL BE AVAILABLE ON-LINE WITH INSTRUCTIONS AND RECORDED WEBINARS EXPLAINING HOW TO USE THEM. WE ALSO WILL DEVELOP SOFTWARE AND CONTROLLERS FOR GROWERS TO IMPLEMENT COST-EFFECTIVE LIGHTING STRATEGIES BASED ON OUR RESEARCH FINDINGS. THESE TOOLS WILL HELP DRIVE INDUSTRY ADOPTION OF ENERGY-EFFICIENT COST-EFFECTIVE LIGHTING TECHNOLOGIES.COLLABORATION WITH LIGHTING COMPANIES WILL BE CRITICAL TO THE SUCCESS OF THE PROJECT AND THESE COMPANIES WILL BE INVITED TO OUR ANNUAL PROJECT MEETINGS TO PROVIDE FEEDBACK ON PROJECT PROGRESS AND DIRECTION. BUT MORE IMPORTANTLY SHARING OUR LATEST RESEARCH FINDINGS WITH LIGHTING COMPANIES WILL ALLOW THEM TO IMPROVE THE FUNCTIONALITY OF THEIR LIGHTS AND PROVIDE PRODUCTS WITH IMPROVED FUNCTIONALITY TO THE INDUSTRY. THIS WILL FACILITATE INDUSTRY ADOPTION OF PROJECT FINDINGS.

** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** ANTHRACNOSE IN WATERMELON AND CUCUMBER CAN SEVERELY IMPACT YIELDS AND INCREASE PRODUCTION COSTS IN THE ABSENCE OF EFFECTIVE CONTROL OPTIONS AND IS A THREAT TO THE LONG-TERM VIABILITY AND PROFITABILITY OF THE U.S. CUCURBIT INDUSTRY. A COORDINATED, MULTI-STATE EFFORT IS REQUIRED TO IMPROVE OUR UNDERSTANDING OF THE RECENT ANTHRACNOSE OUTBREAKS BY DETERMINING PATHOGEN BIOLOGY, POPULATION STRUCTURE, HOST SPECIFICITY, AND FUNGICIDE RESISTANCE PROFILES OF COLLETOTRICHUM SPP. CAUSING SEVERE ANTHRACNOSE OUTBREAKS IN CUCURBIT CROPS. THIS KNOWLEDGE WILL LEAD TO IMPROVED MANAGEMENT STRATEGIES. ASSESSING THE EFFECTS OF SPECIFIC PRODUCTION PRACTICES, ENVIRONMENTAL CONDITIONS, AND INOCULUM ON DISEASE OUTBREAKS CAN AID THE DEVELOPMENT OF PRACTICAL, ECONOMICALLY VIABLE, AND ENVIRONMENTALLY-SOUND STRATEGIES TO LIMIT YIELD LOSSES DUE TO ANTHRACNOSE. OUR TEAM WILL ADDRESS THE PATHOGENS (LEVERAGE GENOMICS AND POPULATION BIOLOGY TO IDENTIFY THECOLLETOTRICHUMSPECIES COMPLEX(ES) AND INOCULUM SOURCES), THE HOST (SCREEN COMMERCIAL VARIETIES AND PI LINES), AND THE ENVIRONMENT (PRODUCTION PRACTICES) THAT CONSTITUTE THE DISEASE TRIANGLE. WE WILL INTEGRATE ECONOMIC ASSESSMENTS AND EXTENSION EFFORTS INTO EACH OBJECTIVE TO FURTHER STRENGTHEN OUR PROJECT. THIS PROJECT MEETS THE LEGISLATIVELY MANDATED SCRI FOCUS AREAS OF EFFORTS TO IDENTIFY AND ADDRESS THREATS FROM PESTS AND DISEASES AND EFFORTS TO IMPROVE PRODUCTION EFFICIENCY, HANDLING AND PROCESSING, PRODUCTIVITY, AND PROFITABILITY.

CELL-TYPE SPECIFIC HEMICELLULOSE STRUCTURES IN THE ROOT CELL WALLS OF ARABIDOPSIS AND BRACHYPODIUM

NEW AWARD - THE CENTER FOR PLANT AND MICROBIAL COMPLEX CARBOHYDRATES AT THE UNIVERSITY OF GEORGIA COMPLEX CARBOHYDRATE RESEARCH CENTER

FUNCTIONAL GENOMICS OF MAIZE CENTROMERES

HEALTHIER TOGETHER: HIGH OBESITY PROGRAM IN GEORGIA

NMR OF CELL SURFACE OLIGOSACCHARIDES

TAS::89 0222::TAS CENTER FOR PLANT AND MICROBIAL COMPLEX CARBOHYDRATES

DISPARITIES IN SELF REGULATION AND SCHOOL READINESS: KINDERGARTEN FOLLOW-UP

EFFECTS OF ANTECEDENT AND RESPONSE VARIABLES ON THE PERSISTENCE OF COMMUNICATION

ENDOCRINOLOGY OF MOSQUITO REPRODUCTION

A TOOLKIT FOR IN VIVO VISUALIZATION/MODULATION OF PLANT CELL WALL POLYSACCHARIDES

GEORGIA NATIVE SEED NETWORK INITIATIVE

TRAINING IN TROPICAL AND EMERGING GLOBAL DISEASES

UNRAVELING THE MAMMALIAN SECRETORY PATHWAY THROUGH SYSTEMS BIOLOGY AND ALGORITHM DEVELOPMENT

GENETICS AND QUANTUM CHEMISTRY AS TOOLS FOR UNKNOWN METABOLITE IDENTIFICATION

FEED THE FUTURE INNOVATION LAB FOR CLIMATE RESILIENT SORGHUM

EVOLUTIONARY GENOMICS OF ABIOTIC STRESS RESISTANCE IN WILD AND CULTIVATED SUNFLOWERS

DEFINING THE GENETIC NETWORK GOVERNING CRYPTOCOCCAL MORPHOLOGICAL TRANSITION

CENTER OF EXCELLENCE FOR FORESTRY, BIODIVERSITY, AND CONSERVATION LEADERSHIP AND GREEN ENTERPRISE DEVELOPMENT IN LIBERIA

PEACH STATE LSAMP - EXTENDING THE STEM PIPELINE IN THE PEACH STATE: MENTORSHIP, RESEARCH AND GRADUATE SCHOOL

** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** THE LONG-TERM GOAL OF THE DIGITAL AND DATA-DRIVEN DEMONSTRATION FARM (4-D FARM) IS TO DEVELOP CLIMATE-SMART PRODUCTION SYSTEMS LEVERAGING RENEWABLE ENERGY, AUTOMATION, INTELLIGENCE AND HUMAN CAPITAL TO MEET THE REQUIRED FOOD AND FIBER NEEDS OF A BURGEONING WORLD POPULATION. MOST CURRENTLY FUNDED RESEARCH IS DRIVEN BY INDIVIDUAL COMMODITY AND DISCIPLINE NEEDS AND RARELY INVESTIGATES INTEGRATING MULTIPLE AGRICULTURAL ENTERPRISES TO IMPROVE FARM RESILIENCE SO THAT THE FARMER DOES NOT HAVE ALL THEIR EGGS IN ONE BASKET. IN THIS PROJECT, DATA-DRIVEN FARM STRATEGIES WILL BE IMPLEMENTED TO CREATE AN INTERDEPENDENT AND DIVERSE CROP/LIVESTOCK ROTATION THAT ADDRESSES THEREDUCED EFFECTIVENESS OF CHEMICAL INPUTS, CLIMATE CHANGE EFFECTS, FEEDING AN INCREASING POPULATION, LOSS OF BIODIVERSITY AND POLLINATORS, WATER QUALITY/QUANTITY, RURAL ECONOMIC STABILITY, LABOR SHORTAGES AND SUPPLY CHAIN DISRUPTIONS. THESE ISSUES ARE ADDRESSED BY THE 4-D FARM: 1) CREATING DATA-DRIVEN, INTEGRATED PRECISION AND CLIMATE-SMART AGRICULTURE WITH INTELLIGENT AUTOMATION TECHNOLOGIES ANDSOLUTIONS, 2) DEVELOPING AND TESTING RESILIENT AGRICULTURAL PRACTICES AND 3) ASSESSING THE SOCIOECONOMIC CONSEQUENCES OF THESE NEW TECHNOLOGIES AND PRACTICES. THE 4-D FARM WILL BE EXECUTED ON A 90-ACRE D.A.T.A. (DEMONSTRATING APPLIED TECHNOLOGY IN AG) FARM AT THE ABRAHAM BALDWIN AGRICULTURAL COLLEGE (ABAC), MULTIPLE EMERGING TECHOLOGY AND DEMONSTRATION SITE'S (ETDS'S) LOCATED ON UNIVERSITY OF GEORGIA (UGA) RESEARCH FARMS, AND A DATA MANAGEMENT AND ANALYSIS CENTER AT THE UGA TIFTON CAMPUS, FUTURE FARMSTEAD CARRIAGE HOUSE. WE HAVE ASSEMBLED AN INTER-DISCIPLINARY TEAM IN PRECISION AND CLIMATE-SMART AGRICULTURE, DATA SCIENCE, LIVESTOCKMANAGEMENT, PEANUT, COTTON, AND CORN PRODUCTION, EXTENSION AND EDUCATION PROGRAMMING, AND AUTONOMOUS AND INTELLIGENT ROVER RESEARCH AND DEVELOPMENT.

STRUCTURE AND FUNCTION IN ALPHA-DYSTROGLYCAN GLYCOSYLATION

ENDING SLAVERY IN SSA: A COLLECTIVE IMPACT APPROACH

SHIP OPERATIONS, R/V SAVANNAH

THE CELL ENVELOPE OF THE MULTI-DRUG RESISTANT PATHOGEN ACINETOBACTER BAUMANNII

5/5 BIPOLAR-SCHIZOPHRENIA NETWORK FOR INTERMEDIATE PHENOTYPES (B-SNIP) - RESUBMISSION - 1

VERTICAL INTEGRATION OF RESEARCH AND EDUCATION IN MATHEMATICS AT THE UNIVERSITY OF GEORGIA

THE ROLE OF POLYPHOSPHATE AND ACIDOCALCISOMES IN TRYPANOSOMA BRUCEI

SECONDARY WALL FORMATION IN FIBER CELLS

ANALYSIS OF E. COLI RIBONUCLEASES AND RNA METABOLISM

PREVENTION AND TREATMENT OF PNEUMOCYSTIS PNEUMONIA

REGULATION OF RNA POLYMERASE II TRANSCRIPTION IN TRYPANOSOMATIDS

MEMBERS OF THE YJGF SUPERFAMILY NEUTRALIZE ENDOGENOUS METABOLIC STRESSORS

TAS::89 0321::TAS BIOREFINERY DEMONSTRATION PROJECT, UNIVERSITY OF GEORGIA, ATHENS