Larc Inc

QUANTITATIVE ANALYSIS OF CANCER-ASSOCIATED EVS - ABSTRACT ALL CELLS IN THE BODY, INCLUDING TUMOR CELLS, RELEASE SMALL VESICLES THAT CAN BE FOUND IN BLOOD, CEREBROSPINAL FLUID, AND EVEN URINE. BECAUSE EACH VESICLE WAS RELEASED BY A SPECIFIC CELL, THEIR ANALYSIS CAN TELL US ABOUT THE CELLS FROM WHICH THEY CAME, INCLUDING WHETHER THAT CELL WAS INFECTED, CANCEROUS, OR MALFUNCTIONING IN SOME WAY. WE WILL DEVELOP ASSAYS AND KITS TO ENABLE CANCER RESEARCHERS TO ANALYZE THESE VESICLES TO IMPROVE THE ABILITY TO UNDERSTAND, DETECT AND TREAT CANCER.

ASSAYS AND KITS FOR MSC-DERIVED EXTRACELLULAR VESICLES

IDENTIFICATION OF CELL TYPE-SPECIFIC EVS FOR NEUROSCIENCE RESEARCH

SBIR PHASE II: ARCTIC ENVIRONMENTAL MODELING WITH AUGMENTATION AND CURATION FROM AN ARTIFICIAL INTELLIGENCE ENGINE -THE BROADER IMPACT OF THIS SMALL BUSINESS INNOVATION RESEARCH (SBIR) PHASE II PROJECT WILL ADDRESS THE GROWING NEED FOR ACCURATE MODELS AND FORECASTS OF THE ARCTIC. AS ARCTIC MARITIME OPERATIONS SUCH AS FISHING, SHIPPING, AND MARICULTURE OF KELP ARE INCREASINGLY IMPACTED BY UNPRECEDENTED CLIMATE CHANGE, TRADITIONAL MODELING TECHNIQUES ARE UNABLE TO SUPPORT THESE NEW DEMANDS. ECOSYSTEMS ARE NOT STATIC, AND THEIR UNPREDICTABILITY HINDERS SAFE AND SUSTAINABLE ECONOMIC DEVELOPMENT FOR COMMUNITIES. THIS MODELING APPROACH SUPPORTS THE ECONOMIC COMPETITIVENESS FOR ALASKAN FISHERIES BY INCREASING TRANSPARENCY OF RESOURCES ON SHORT TIMESCALES (PRECISION FISHING) AND LONG TIMESCALES (ECOSYSTEM MODELING). THE RESULTS COULD BE USED TO IDENTIFY NEW AND EMERGING LOCATIONS FOR FISHERIES, UNDER- OR OVER-FISHED LOCATIONS, AND DIFFERENCES BETWEEN LOCATIONS THAT CAN BE RESTORED OR THOSE THAT THE ECOSYSTEM HAS SHIFTED AWAY FROM SUPPORTING. BY APPLYING DYNAMIC ECOLOGY INFORMATION, THIS PROJECT CAN PROVIDE TOOLS TO IMPROVE MANAGEMENT OF OCEAN RESOURCES, WHICH COULD INCREASE INDUSTRY PROFITS WHILE SIMULTANEOUSLY RAISING THE TOTAL HARVESTABLE BIOMASS. THE SMALL BUSINESS INNOVATION RESEARCH (SBIR) PHASE II INNOVATION IS TO CREATE AND REFINE AN ARTIFICIAL INTELLIGENCE (AI) ENGINE CAPABLE OF GENERATING CUSTOM ENVIRONMENTAL MODELS, MAKING NEW AND EMERGING SCIENCE QUICKLY ACCESSIBLE TO THE PEOPLE AND COMMUNITIES THAT NEED THE SOLUTIONS. THE AI-PRODUCED SOFTWARE WILL INTEGRATE MULTIPLE TYPES OF SCIENTIFIC TECHNIQUES FROM THE FIELDS OF NEARSHORE BATHYMETRY MODELS, HABITAT MAPPING, PRECISION FISHING, AND ECOSYSTEM BASED FISHERIES MANAGEMENT (EBFM) TOOLS. SCALING THE GENERATION OF TAILORED MODELS PROVIDES COST EFFECTIVE, ADAPTABLE, AND ACCURATE SOLUTIONS TO OCEAN ENVIRONMENTAL CHALLENGES. SUCCESSFULLY EXECUTING THIS PLAN WILL REQUIRE A COMBINATION OF TECHNICAL AND COMPUTING SKILLS; NUMERICAL MODELING EXPERTISE; SIGNIFICANT SCIENTIFIC LITERACY IN REMOTE SENSING, BATHYMETRY, SEA ICE, PHYSICAL OCEANOGRAPHY, AND FISHERIES SCIENCE; AND THE DEVELOPMENT AND TRAINING OF NOVEL NEURAL NETWORK ARCHITECTURES. IN PHASE I WORK, REMOTE SENSING FROM SATELLITES WAS USED TO MAP THE NEARSHORE IN THE PROTOTYPE AI ENGINE. REMOTE SENSING FROM NEW SATELLITE RESOURCES HAS ENABLED THIS EFFORT OF A DEEPER UNDERSTANDING OF THE WORLD?S REMOTE LOCATIONS, LIKE THE ARCTIC OCEAN. THESE DATA DESERTS CAN LEVERAGE SATELLITES AND POCKETS OF INDIGENOUS TRADITIONAL KNOWLEDGE TO BUILD PRODUCTIVE, NEW ECONOMIES THAT ARE RESILIENT AND ADAPTABLE. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

BIL MAXIMIZATION OF RECOVERY OF KEY MATERIALS FROM END-OF-LIFE PHOTOVOLTAIC PANELS THIS PROJECT’S GOAL IS TO ENHANCE PHOTOVOLTAIC (PV) RECYCLING CAPABILITIES BY ACHIEVING LARGER AND HIGHER-QUALITY YIELDS OF GLASS, SILVER, AND SILICON THROUGH DEVELOPING INNOVATIVE, NEW PROCESSES OF RECOVERY FROM END-OF-LIFE (EOL) PV MODULES. THE TECHNICAL OBJECTIVES OF THIS PROJECT ARE TO ACHIEVE YIELD AND PURITY MILESTONES OF RECOVERED MATERIALS THROUGH RESEARCH AND DEVELOPMENT (R&D) EFFORTS, AND TO ANALYZE THE RECYCLING PROCESS ECONOMICALLY AND ENVIRONMENTALLY TO PREPARE SOLARCYCLE FOR SCALING THE TECHNOLOGY. THIS PROJECT WILL HAVE THE FINAL RESULT OF PAVING THE WAY FOR MORE EFFECTIVE PV RECYCLING TECHNOLOGY BY INCREASING THE RESEARCH ON RECYCLING PROCESSES AND BY QUANTIFYING PV RECYCLING’S COMMERCIAL AND ENVIRONMENTAL VIABILITY. THIS PROJECT WILL FACILITATE RECOVERY OF MORE VALUE FROM END- OF-LIFE SOLAR PANELS, ENCOURAGING RECYCLING OVER LANDFILLING. EFFECTIVE MATERIAL RECOVERY OF PV MODULES IS A NECESSITY FOR DEVELOPING A CIRCULAR ECONOMY AND LOWERING TOTAL COSTS OF SOLAR POWER GENERATION.

VOZ Y VIDA (VOICE AND LIFE)

SEC. 9007 REAP-RENEW ENERGY SYS GUAR. LOAN & GRANT COMBO (MAN)

DRUG FREE COMMUNITY SUPPORT PROGRAM

SBIR PHASE I: NEAR SHORE BATHYMETRY AND COASTLINE MODELING IN THE ARCTIC

REAP ENERGY EFFICIENCY IMPROVEMENT (EEI) GRANT UNRESTRICTED AMOUNT

CELLARCUS INNOVATION CORPS AT NIH

HIGHER BLENDS INFRASTRUCTURE INCENTIVE PROGRAM GRANT - MANDATORY

ASSISTANCE TO FIREFIGHTERS GRANT

STAFFING FOR ADEQUATE FIRE AND EMERGENCY RESPONSE (SAFER)

VILLAGE OF LARCHMONT SAFETY ACTION PLAN

OTHER-TECH

SUSAN HARWOOD GRANTS

SUSAN HARWOOD GRANTS

SUSAN HARWOOD GRANTS

ASSISTANCE TO FIREFIGHTERS GRANT

OTHER-TECH

ASSISTANCE TO FIREFIGHTERS GRANT

SUSAN HARWOOD GRANTS

ASSISTANCE TO FIREFIGHTERS GRANT

OTHER-TECH

RCDG - VALUE-ADDED PRODUCT MARKET DEVELOPMENT GRANTS

ASSISTANCE TO FIREFIGHTERS GRANT

HARMONIC GENERATION AND OPTICAL LIMITING FROM METAL-DIELECTRIC MULTI-LAYER STRUCTURES

GRANT TO COVER THE PURCHASE OF SUPPLIES FOR THE MUSEUM INTERNSHIP PROGRAM IS AMENDED TO INCLUDE THE PURCHASE OF OTHER SUPPLIES.

A GRANT AGREEMENT TO ASSIST THE VILLAGE OF LARCHMONT, NY WITH FEDERAL STORMWATER REGULATIONS COMPLIANCE BY PURCHASING EQUIPMENT FOR THE INSPECTION AN

ASSISTANCE TO FIREFIGHTERS GRANT

ASSISTANCE TO FIREFIGHTERS GRANT